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Notice Extension Expiration date PA-11-182 Research Ethical Issues Biomedical, Social Behavioral Research R21)" Notice Number: NOT-OD-14-033 Key Dates Release Date: December 13, 2013 Related Announcements PA-11-182 Issued National Institutes Health NIH) National Cancer Institute NCI) National Human Genome Research Institute NHGRI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Allergy Infectious Diseases NIAID) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Center Complementary Alternative Medicine NCCAM) Office Behavioral Social Sciences Research OBSSR) Purpose purpose this Notice to inform interested applicants the expiration date PA-11-182 quot;Research Ethical Issues Biomedical, Social Behavioral Research R21)" being extended until 8, 2015.  the exception NHLBI will continue participating, remaining participating NIH Institutes, Centers Offices ICOs) the same described the FOA.  Please note the mission statement the National Center Complementary Alternative Medicine NCCAM) is listed Part 2, Section Funding Opportunity Description under quot;NIH IC Mission Areas" been changed the following: mission NCCAM to define, through rigorous scientific investigation, usefulness safety complementary alternative medicine interventions their roles improving health and health care. Inquiries information the FOA, prospective applicants should contact Scientific/Research contact the relevant NIH ICO identified the end the FOA. General inquiries the FOA about extension Notice, be directed to: Ann Hardy Office Extramural Programs Telephone:  301-435-2690 Email: hardyan@od.nih.gov nbsp;

Notice National Institute Nursing Research NINR) Participation RFA-HG-14-001 BD2K-LINCS-Perturbation Data Coordination Integration Center DCIC) U54)" Notice Number: NOT-NR-14-003 Key Dates Release Date: December 6, 2013 Related Announcements RFA-HG-14-001 Issued National Institute Nursing Research NINR) Purpose purpose this Notice to inform potential applicants the National Institute Nursing Research NINR) participating RFA-HG-14-001 quot;BD2K-LINCS-Perturbation Data Coordination Integration Center DCIC) U54).” following sections of RFA-HG-14-001 have updated reflect participation NINR this FOA. Part 1. Overview Information Components Participating Organizations National Cancer Institute NCI) National Eye Institute NEI) National Heart, Lung, Blood Institute NHLBI) National Human Genome Research Institute NHGRI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Allergy Infectious Diseases NIAID) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Diabetes Digestive Kidney Diseases NIDDK) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Library Medicine NLM) National Institute Minority Health Health Disparities NIMHD) National Center Complementary Alternative Medicine NCCAM) Office Strategic Coordination Common Fund) Catalog Federal Domestic Assistance CFDA) Number(s) 93.172; 93.121; 93.846; 93.213; 93.839; 93.838; 93.837; 93.233; 93.866; 93.847; 93.307; 93.399; 93.396; 93.395; 93.394; 93.393; 93.310; 93.173; 93.867; 93.113; 93.856; 93.855; 93.242; 93.273; 93.853; 93.879; 93.279; 93.286; 93.361 Inquiries Please direct inquiries to: Lyn Hardy, PhD, RN National Institute Nursing Research NINR) Telephone: 301) 594-5976 Email: hardylr@mail.nih.gov nbsp;

Notice NINDS Participation RFA-HD-14-033 Centers Collaborative Research Fragile X U54)" Notice Number: NOT-NS-14-004 Key Dates Release Date: November 26, 2013 Related Announcements RFA-HD-14-033 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to inform potential applicants the participation the National Institute Neurological Disorders Stroke NINDS) RFA-HD-14-033 quot;Centers Collaborative Research Fragile X U54)". following sections of RFA-HD-14-033 have updated reflect participation NINDS this FOA. Part 1. Overview Information  Components Participating Organizations Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) Catalog Federal Domestic Assistance CFDA) Number(s) 93.865, 93.242, 93.853  Part 2.II. Award Information Funds Available Anticipated Number Awards NICHD partner components NIH intend commit following estimated total amounts FY 2014 support approximately 4 center awards: NICHD, 4 million total costs NIMH, 2 million total costs NINDS, 1 million total costs Part 2.VII. Agency Contacts Scientific/Research Contact(s) Laura Mamounas, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5745 Email: mamounal@ninds.nih.gov Website: http://www.ninds.nih.gov/funding/areas/neurogenetics/index.htm Financial/Grants Management Contact(s) Tijuanna Decoster, MPA National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-9231 Email: decostert@ninds.nih.gov Inquiries Please direct inquiries to: Laura Mamounas, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5745 Email: mamounal@ninds.nih.gov Website: http://www.ninds.nih.gov/funding/areas/neurogenetics/index.htm nbsp;

Collaborative Research Computational Neuroscience CRCNS) Innovative Approaches Science Engineering Research Brain Function R01) Notice Number: NOT-MH-14-002 Key Dates Release Date: November 21, 2013 Related Announcements NSF 14-504 Issued National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Drug Abuse NIDA) National Institute Deafness Other Communication Disorders NIDCD) National Eye Institute NEI) National Institute Biomedical Imaging Bioengineering NIBIB) National Institute Alcohol Abuse Alcoholism NIAAA) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Center Complementary Alternative Medicine NCCAM) National Science Foundation NSF) Federal Ministry Education Research Bundesministerium für Bildung und Forschung, BMBF), Germany French National Research Agency Agence Nationale de la Recherche, ANR), France U.S.-Israel Binational Science Foundation BSF), Israel Purpose Notice announces reissue a joint initiative, Collaborative Research Computational Neuroscience CRCNS), among seven National Science Foundation NSF) Directorates Offices DOs), nine participating National Institutes Health NIH) Institutes Centers ICs).  CRCNS announcement released under NSF 14-504 http://www.nsf.gov/pubs/2014/nsf14504/nsf14504.htm). announcement supersedes NSF 11-505 NFS 12-114:  Collaborative Research Computational Neuroscience CRCNS) – Innovative Approaches Science Engineering Research Brain Function. German Federal Ministry Education Research Bundesministerium für Bildung und Forschung, BMBF http://www.bmbf.de/), French National Research Agency Agence Nationale de la Recherche, ANRS http://www.agence-nationale-recherche.fr), the U.S.-Israel Binational Science Foundation BSF http://www.bsf.org.il) now formal partners this program, along the NSF the NIH.  NIH, CRCNS now affiliated the NIH Blueprint Neuroscience Research http://neuroscienceblueprint.nih.gov). Computational neuroscience provides theoretical foundation a rich set technical approaches understanding complex neurobiological systems, building the theory, methods, findings computer science, neuroscience, numerous disciplines.  Through CRCNS program, participating NSF DOs, NIH ICs, BMBF, ANRS BSF support innovative interdisciplinary collaborative research make significant advances the understanding structures functions the nervous system, mechanisms underlying nervous system disorders, computational strategies used the nervous system. participating agencies recognize need research focuses integrating computational models methods neuroscience.  solicitation designed encourage new collaborations this interface.  Appropriate scientific areas investigations those are currently supported NSF NIH, related the missions the agencies.  participating this broadly based program cooperation between agencies, NIH focus creating new research teams biomedical quantitative scientists explore questions directly relevant the missions participating NIH ICs. classes proposals be considered response this solicitation: Research proposals - describing collaborative research projects Data Sharing Proposals - enable sharing data other resources Domestic international projects be considered. detailed the solicitation, international components collaborative projects be funded parallel the participating agencies.  Opportunities parallel funding available US-German Research Proposals, US-German Data Sharing Proposals; US-French Research Proposals, US-French Data Sharing Proposals; US-Israel Research Proposals. Appropriate scientific areas investigations those related the mission participating funding agencies.  Questions concerning particular project’s focus, direction relevance a participating funding agency should addressed the appropriate person the list agency contacts the NSF Program Solicitation NSF 14-504, http://www.nsf.gov/pubs/2014/nsf14504/nsf14504.htm). computational research supported under program must impact on, relate biological processes, optimally generate hypotheses are testable biological studies.  is expected that:  1) applications include collaborations among computational and/or modeling experts, theorists, experimental neuroscientists; 2) collaborations involve dynamic and, possibly, protracted period model theory development refinement, intense interaction among scientists engineers different disciplines; 3) development testing new models theories provide framework the design experiments the generation new hypotheses can help reveal mechanisms underlying normal disease states the nervous system, 4) development distribution professional quality software tools e.g., modeling algorithms analytic tools). Award Information Award sizes research projects expected range approximately 100,000 250,000 per year direct costs, durations three five years.  awards be the smaller end this range; award exceed 250,000 per year direct costs.  Applicants strongly discouraged requesting greater budgets are necessary the activities being proposed.  is estimated data sharing projects range approximately 25,000 100,000 cumulative award size a one- three-year project.  Estimated program budget, number awards average award size duration subject the availability funds. Upon conclusion the review process, meritorious applications be recommended funding either participating NSF DOs NIH ICs, the option the agencies, the applicant.  Data sharing proposals be funded only NSF.  Subsequent grant administration procedures be accordance the individual policies the awarding agency. Eligibility Information Limit Number Proposals per PI Co-PI: 2 response this solicitation, investigator participate PI Co-PI no than proposals per review cycle.  the event a PI Co-PI does appear either these roles more two proposals, proposals include person a PI Co-PI be returned without review.  limit applies all PIs Co-PIs, based inside outside the United States. Proposal Preparation Submission Instructions Applications submitted response this program announcement/solicitation should prepared submitted accordance the general guidelines contained the NSF Grant Proposal Guide GPG).  Applications must submitted the NSF, to NIH.  complete text the GPG available electronically the NSF Web Site at: http://www.nsf.gov/publications/pub_summ.jsp?ods_key=gpg.   Applicants reminded identify program announcement number 14-504) the program announcement block the NSF Cover Sheet Proposal the National Science Foundation.  Compliance this announcement critical determining relevant proposal processing guidelines.  Failure submit information delay processing. Budgetary Information Cost sharing not required NSF proposals submitted under Program Solicitation.  Budgets should include travel funds the PI team members attend annual CRCNS Principal Investigators' meeting. NIH Process those proposals are selected potential funding participating NIH ICs, PI be required resubmit proposal an NIH-approved format directly the Center Scientific Review http://www.csr.nih.gov/) the NIH.  PIs invited resubmit NIH receive further information resubmission procedures the NIH.  applicant not allowed increase proposed budget change scientific content the application the resubmission the NIH.  applicants be expected utilize Multiple Program Director/Principal Investigator option the NIH http://grants.nih.gov/grants/multi_PI/) appropriate.  NIH applications be entered the NIH IMPAC II system.  results the review be presented the involved IC's National Advisory Councils the second level review.  Subsequent the Council reviews, NIH ICs make funding determinations selected awards be made.  Subsequent grant administration procedures NIH awardees, including those related New Early Stage Investigators http://grants.nih.gov/grants/new_investigators/) be accordance the policies NIH.  Applications selected NIH funding use NIH R01 funding mechanism. Inquiries Written telephone inquiries encouraged.  Please the NSF program announcement names contact information each the participating NSF DOs and/or NIH ICs http://nsf.gov/pubs/2014/nsf14504/nsf14504.htm.   nbsp;

Notice Intent Publish Blueprint Program Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences BP-ENDURE) R25)" Notice Number: NOT-NS-14-002 Key Dates Release Date: November 13, 2013   Estimated Publication Date Announcement: February 2014 First Estimated Application Due Date: 2014  Earliest Estimated Award Date: February 2015    Earliest Estimated Start Date: April 2015 Related Announcements None Issued NIH Blueprint Neuroscience Research http://neuroscienceblueprint.nih.gov) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) National Institute General Medical Sciences NIGMS) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Center Complementary Alternative Medicine NCCAM) Office Behavioral Social Sciences Research OBSSR) Purpose National Institutes Health NIH) Blueprint Neuroscience Research intends reissue Funding Opportunity Announcement FOA) receipt new renewal applications its research education program neuroscience focused undergraduates. overall objective this funding opportunity be increase number undergraduate participants diverse groups successfully enter complete Ph.D. degree programs the neurosciences. accomplish goal, initiative support development collaborative research education partnerships increase participants’ awareness interest the neurosciences, develop participants’ scientific knowledge research skills would allow to progress transition more advanced neuroscience related research education training activities, establish working networks within existing Ph.D. degree granting NIH-supported predoctoral T32 neuroscience programs. Notice being provided allow potential applicants sufficient time develop meaningful collaborations responsive projects.  FOA expected be published late February 2014 an expected application due date May 2014. FOA utilize R25 activity code. Research Initiative Details new FOA expected continue overarching objective the original FOA: RFA-MH-10-070. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: Michelle D. Jones-London, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-451-7966 Email: jonesmiche@mail.nih.gov nbsp;

Clarification Eligibility Applications PAR-13-362 Neurological Sciences Academic Development Award K12)" Notice Number: NOT-NS-14-003 Key Dates Release Date: November 4, 2013 Related Announcements PAR-13-362 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Neurological Sciences Academic Development Award NSADA) K12 award designed support individuals trained pediatric neurology foster careers clinician-scientists. Typically, individuals supported while a residency program. Whereas is anticipated applications generally from accredited medical school, is recognized many accredited medical schools affiliated one more hospitals, that funding residents be managed an affiliated hospital. list eligible organizations PAR-13-362 NSADA K12) includes only Higher Education Institutions." purpose this Notice to inform community a hospital manages funding pediatric neurology residents also eligible be applicant institution this FOA. However, applicant institution must affiliated an accredited medical school the PD/PI the NSADA K12 application must an appointment an appropriate academic department the medical school an appointment the applicant institution. Inquiries Please direct inquiries to: Stephen Korn, Ph.D. Director, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-4188 Email: korns@ninds.nih.gov    

Notice Updates the National Robotics Initiative NRI) Notice Number: NOT-EB-13-005 Key Dates Release Date: October 29, 2013 Related Announcements NOT-EB-14-008 NOT-EB-12-006 Issued National Institutes Health NIH) National Eye Institute NEI) National Institute Aging NIA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Science Foundation NSF) National Aeronautics Space Administration NASA) U.S. Department Agriculture USDA) Purpose Notice updates supersedes previous Guide Notice, NOT-EB-12-006, published the NIH Guide, September 21, 2012. NIH collaborating a multi-agency funding opportunity, National Robotics Initiative NRI) http://www.nsf.gov/funding//pgm_summ.jsp?pims_id=503641), whose goal to accelerate development use robots the United States work beside, cooperatively with, people http://www.nsf.gov/pubs/2014/nsf14500/nsf14500.htm). Innovative robotics research applications emphasizing realization such co-robots acting direct support a human supported multiple agencies the federal government including National Institutes Health NIH), National Science Foundation NSF), National Aeronautics Space Administration NASA), the U.S. Department Agriculture USDA). initiative facilitate development the next generation robotics, particularly co-robotics, encourage existing new communities focus innovative application areas. Collaboration between academic, industry, non-profit other organizations strongly encouraged establish better linkages between fundamental science technology development use.   NIH encourages robotics research technology development enhance health, lengthen life reduce illness disability. Specifically, participating NIH institutes interested targeting solicitation tosupport development assistive robotic technology achieve functional independence humans; improve quality life; assist behavioral therapy personalized care; promote wellness/health. most significant challenges be addressing safety issues, especially applications be used home-based long-term care settings where integration complex systems be required. Additionally, assistive robots need quickly adapt changes the user the environment. Human assistive devices should designed assist healthcare providers as well the individuals needing care. Development robotic applications important NIH because their potential significant impact healthcare the future. Human assistive devices revolutionize healthcare the next 20 years much personal electronics changed our daily lives the past decades. Affordable accessible robotic technology facilitate wellness personalized healthcare. Continual health assessment personalized intervention the potential offset shrinking size the healthcare workforce the growing elderly disabled population. the future, assistive robotics enable people engage all aspects human life endurance dignity. Examples assistive robotic technology development include are limited to: - Homecare long-term personalized care robots - Robotic wellness/health promotion maintenance - Robotic behavioral therapy - Mobility, manipulation, visual, communication cognitive aids - Assistive robotics eliminate health disparities across populations developing appropriate assistive co-robotic technologies, applicants should consider following basic characteristics: effectiveness, affordability, cultural acceptability, accessibility those need them.  Applicants should describe these technologies address healthcare needs the end user healthy individuals, persons disability, or health disparity populations). robotic applications promoted this solicitation for non-operative settings.  NIH still interested supporting robotics surgical health interventions, however, in response solicitation.  Applicants interested this area should send inquiries the NIH program contacts listed below.  Applicants encouraged utilize resources provided NIH Clinical Translational Science Award CTSA) Program conducting proposed research. Award Information Award sizes NIH funded research projects expected range approximately 100,000 250,000 per year direct costs, durations one five years.  award exceed 250,000 per year direct costs. Estimated program budget, number awards average award size duration subject the availability funds.  Determination awards based three criteria: 1) availability funds, 2) program priorities, 3) scientific merit. Subsequent grant administration procedures be accordance the policies the awarding Institute. Application Preparation Submission Instructions Applications submitted response this program announcement/solicitation should prepared submitted accordance the general guidelines contained the NSF Grant Proposal Guide GPG).  Applications must submitted the NSF, to NIH.  complete text the GPG available electronically the NSF Web Site at: http://nsf.gov/publications/pub_summ.jsp?ods_key=gpg. Applicants reminded identify NSF program announcement number the program announcement block the NSF Cover Sheet Proposal the National Science Foundation.  Compliance this announcement critical determining relevant application processing guidelines.  Failure submit information delay processing. Budgetary Information Cost sharing not required applications submitted this funding opportunity. Budgets should include travel funds the PD/PI team members attend annual NRI Principal Investigators' meeting. NIH Process goal this activity to involve multiple agencies using application one review. meet NIH requirements, those applications are identified potential funding participating NIH Institutes Centers ICs), applicant organization be required submit R01 application an NIH-approved format directly the Center Scientific Review http://public.csr.nih.gov/) the NIH.  PDs/PIs invited submit NIH receive further information submission procedures the NIH. NIH application not allowed increase proposed budget change scientific content the application the converted submission the NIH. The summary statement be presented the involved IC's National Advisory Council the second level review. Subsequent the Council review, NIH ICs make funding determinations selected awards be made. Grant administration procedures NIH awardees, including those related New Early Stage Investigators http://grants.nih.gov/grants/new_investigators/) be accordance the policies NIH. Please note applications be submitted review the NSF January 21, 2014. Notification applications selected potential funding the participating NIH ICs be received the beginning April 2014.  converted submission NIH be due April 14, 2014, will an extremely short conversion time.  applicant organization want work closely their Sponsored Programs Office assure timely submission during narrow submission window. earliest project start date be July 1, 2014. Inquiries Written telephone inquiries encouraged.  NIH Program contacts listed below. Please the NSF program announcement names contact information each the participating NSF Directorates http://www.nsf.gov/nri.   Louis Quatrano, Ph. D. Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) Phone:  301-402-4221 Email: quatranl@mail.nih.gov http://www.nichd.nih.gov/    Grace C.Y. Peng, Ph.D., National Institute Biomedical Imaging Bioengineering NIBIB) Phone: 301-451-4778  Email: penggr@mail.nih.gov   http://www.nibib.nih.gov/   Tom Greenwell, Ph.D. National Eye Institute NEI) Phone: 301-451-2020 Email:  greenwellt@nei.nih.gov http://www.nei.nih.gov/ Lyndon Joseph, Ph.D National Institute Aging, NIH, DHHS NIA) Phone: 301-496-6926 Email: Josephlj@nia.nih.gov          http://www.nia.nih.gov/       Roger L. Miller, Ph.D. National Institute Deafness Other Communication Disorders NIDCD) Phone: 301-402-3458 Email:  millerr@nidcd.nih.gov   http://www.nidcd.nih.gov/ Daofen Chen, Ph.D. National Institute Neurological Disorders Stroke NINDS) Phone: 301-496-9964 Email: daofen.chen@nih.gov http://www.ninds.nih.gov/ Paul A. Cotton, PhD, RD, Program Director National Institute Nursing Research NINR) Phone: 301-402-6423 Email: Paul.Cotton@nih.gov     http://www.ninr.nih.gov/       

Notice Correct Anticipated Application Due Date NINDS Exploratory Grant Program Parkinson's Disease Research P20) Notice Number: NOT-NS-14-001 Update: following update relating this announcement been issued: 19, 2014 - Notice NOT-NS-14-033. Notice update information provided. Key Dates Release Date: October 24, 2013 Related Announcements NOT-NS-13-040 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to correct anticipated application due date the NINDS Exploratory Grant Program Parkinson's Disease Research P20).  anticipated application due date be April 2014. other aspects NOT-NS-13-040 remain unchanged. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email: sieberb@ninds.nih.gov  

Notice the Extension the Response Date NINDS's Request Information RFI): Advancing Research Parkinson's Disease 2014 Notice Number: NOT-NS-13-042 Key Dates Release Date: September 26, 2013 Related Announcements NOT-NS-13-035 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice extends expiration date NOT-NS-13-035 quot;Request Information RFI): Advancing Research Parkinson's Disease 2014". Accordingly, responses the RFI be accepted an additional month: Current Expiration Date: September 30, 2013 New Expiration Date: October 31, 2013 other aspects the RFI remain same. RFI responses must submitted electronically http://www.ninds.nih.gov/funding/RFI-PD.htm. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Email: sieberb@ninds.nih.gov

Notice Intent Publish Funding Opportunity Announcement the NINDS Exploratory Grant Program Parkinson's Disease Research P20) Notice Number: NOT-NS-13-040 Update: following update relating this announcement been issued: 19, 2014 - Notice NOT-NS-14-033. Notice update information provided. October 24, 2013 - Notice NOT-NS-14-001. Notice Correct Anticipated Application Due Date. Key Dates Release Date: September 23, 2013   Estimated Publication Date Announcement: November 2013  First Estimated Application Due Date: January 2014  New Date April 2014 per NOT-NS-14-001) Earliest Estimated Award Date: July 2014  Earliest Estimated Start Date: July 2014 Related Announcements None Issued National Institute Neurological Disorders Stroke NINDS) Purpose Parkinson's disease PD) a chronic, progressive movement disorder affects least half million people the United States, well the relatives friends care them. average age onset during sixth decade, although earlier onset also possible, the incidence PD expected increase the population ages. While significant research advances continue, full complexity PD etiology not yet evident. Moreover, currently available treatments primarily symptomatic, neither slow halt disease progression. Challenges posed the inherent complexity PD often best addressed multidisciplinary research teams working tandem surmount obstacles seize opportunities advance knowledge improve treatment. However, development an effective team, identification an optimal strategy collection preliminary data address particular challenge PD require dedicated time resources. Therefore, National Institute Neurological Disorders Stroke NINDS) solicit Exploratory Grant P20) applications proposing planning and initiation collaborative research activities advance PD research. goal this program to formalize collaborative structures establish foundation research discovery necessary address intransigent issues PD research, such successful exploratory studies lead a subsequent application support a collaborative, multidisciplinary NINDS Morris K. Udall Center Excellence P50). foster development innovative research collaborations, FOA provide support new projects, continuation projects have already initiated. Notice being provided allow potential applicants sufficient time develop meaningful collaborations responsive projects.  FOA expected be published Fall 2013 an expected application due date January 2013. Research Initiative Details NINDS Exploratory Grant Program provide support collaborative, multidisciplinary groups plan future application elucidation, disease modification prevention Parkinson's disease. most compelling P20 applications address unifying theme pursue focused, consortium-based strategy develop research approach which near-term, significant progress be made. Collaborative teams include expertise required address critical gaps knowledge are barriers therapeutic translation research findings; collaborations between public private sector encouraged. Related activities include preliminary data generation, pilot feasibility studies other organizational activities necessary prepare full scale NINDS Udall Center application. Proposed pilot studies must defined within application. Proposals include any combination basic, translational clinical components required the planning a subsequent application. Interventional clinical trials not included this FOA. Applicants also expected address significance outcomes PD research treatment should subsequent full-scale Udall Center grant awarded. Successful applicants establish proof-of-concept” experimental framework could generalized organize subsequent research efforts meet specific challenges PD research. Applicants request maximum annual direct costs 300,000 per year, up three years. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email: sieberb@ninds.nih.gov