Research Opportunity Announcements

A Research Opportunity Announcement (ROA) is a public document that announces the availability of an Other Transaction (OT). It provides the initiative’s purpose, type of award, instructions on how to apply, due date for proposals or applications, and research opportunity number.

Information about Other Transactions can be found on the Grants & Funding  website.

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This is a preview of the Data Table. Only the first three rows are displayed.
Title OTA Number Purpose OTA Category Contact
Platform Trials of Thrombectomy in Acute Stroke (OT2) OTA-22-001 NINDS is interested in establishing master protocols to enable platform trials in thrombectomy in acute stroke using a seamless rolling approach to be conducted within the existing NIH StrokeNet infrastructure. Trials that further refine patient groups that do or do not benefit from mechanical thrombectomy, and using which management approaches, will also open the door to testing neuroprotectant strategies in an efficient, timely, and cost-effective manner. This ROA will establish the groundwork to include the master protocol for platform trials with the NIH StrokeNet. StrokeNET Scott Janis, PhD
HEAL Initiative: EPPIC-Net Pain Research Asset Application (OT2) OTA-22-002 The purpose of this research opportunity announcement (ROA) is to invite Stage 1 preliminary applications for submission of therapeutics, including but not limited to, drugs, biologics, and devices as well as biomarkers (termed assets) for study in the HEAL Initiative’s EPPIC-Net. HEAL/EPPIC-Net Barbara Karp, MD
HEAL Initiative: EPPIC-Net Pain Research Asset Application- Dossier OTA-20-002 The purpose of this research opportunity announcement (ROA) is to invite Stage 2 Dossier applications for submission of assets that have successfully passed Stage 1 preliminary application review. EPPIC-Net applications are reviewed in a three-stage process. applications to Stages 2 & 3 will be by invitation only. HEAL/EPPIC-Net Barbara Karp, MD
HEAL Initiative: EPPIC-Net Pain Research – Application for Clinical Trials and Related activities (OT2) OTA-20-008 The purpose of this research opportunity announcement (ROA) is to fund early phase clinical trials of pain therapeutic assets and its related activities. The ROA accepts applications from the EPPIC-Net CCC, working in conjunction with the EPPIC-Net DCC and SCCs, for funding of clinical trial preparatory activities not covered by EPPIC-Net U24 agreements to the CCC, DCC, or Specialized Clinical Centers (Hubs/Spokes), as well as applications for specific clinical trials. HEAL/EPPIC-Net Barbara Karp, MD
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Form Approved OMB# 0925-0648 Exp. Date 06/2024