| Small Business Innovation Research (SBIR) | Small Business Technology Transfer (STTR) | |
|---|---|---|
| Percent of R&D Budget | 3.2% | 0.45% |
| Partnerships | Research partnerships are allowed | Partnership with a non-profit research institution is required (e.g. university) |
| Work Requirement |
Small businesses may outsource:
|
Minimum work requirements:
The remaining work may be done by either or outsourced |
| Principal Investigator (PI) | Primary employment (>50%) must be with the small business | PI must be employed by either the partnering research institution or small business (minimum 10% effort) |
| Phase I | A Phase I award helps you focus on the feasibility, technical merit, and commercial potential of your research project. |
|---|---|
| Phase II | A Phase II award lets you continue the research and development efforts initiated in Phase I. Once you’ve reached your Phase I milestones, you can apply for a Phase II award, even before the end of the Phase I award. You may submit your application for a Phase II award up to six receipt dates after your Phase I budget period expires. |
| Fast-Track | The fast-track process allows you to submit both Phase I and Phase II in one application for review. The Fast -Track mechanism can minimize the funding gap between phases but requires a fully developed Phase II application/commercialization plan at the time of submission. |
| Direct-to-Phase II (SBIR Only) | If your project has already demonstrated Phase 1 equivalent feasibility, you can apply for a Direct-to-Phase II award and bypass Phase I. |
| Phase IIB | NINDS offers Phase IIB awards for Phase II projects that require extraordinary time and effort beyond the standard Phase II period of 2 years. Refer to the SEED Phase IIB FAQs for more information. |
| Commercialization Readiness Pillot (CRP) Program | The Commercialization Readiness Pilot (CRP) Program provides awarded Phase II or Phase IIB small businesses technical assistance and funding for late-stage development. Read more about the CRP program. |
| R41: Small Business Technology Transfer (STTR) Grant, Phase I | Supports cooperative R&D projects between small business concerns and research institutions, limited in time and amount, to establish the technical merit and feasibility of ideas that have potential for commercialization. |
|---|---|
| R42: Small Business Technology Transfer (STTR) Grant, Phase II and Fast-Track | Supports in-depth development of cooperative R&D projects between small business concerns and research institutions, limited in time and amount, for which feasibility has been established in an STTR Phase I project and which have the potential for commercialization. |
| R43: Small Business Innovation Research (SBIR) Grant, Phase I | Supports projects to establish the technical merit and feasibility of R&D ideas which may lead to a commercial product or service and to determine the quality of performance of the small business awardee organization. |
| R44: Small Business Innovation Research (SBIR) Grant, Phase II and Fast-Track | Small Business Innovation Research (SBIR) Grant, Phase II, and Fast-Track: supports in-depth development of R&D ideas for which feasibility was established in Phase I projects and which may ultimately lead to a commercial product or service. |
| U44: Cooperative Small Business Awards | Cooperative Small Business Awards. These are milestone-driven and involve NIH program staff’s participation in developing the project plan, monitoring research progress, and appropriate go/no-go decision-making. See more information on translational research programs which utilize this mechanism. |
NINDS Small Business Program Contact Information
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Emily Caporello, Ph.D. Director emily.caporello@nih.gov Annette Gilchrist, Ph.D. Program Director, Drug Development annette.gilchrist@nih.gov Jessica Forbes, Ph.D. Health Program Specialist jessica.forbes@nih.gov Taryn Aubrecht, Ph.D. Program Director, Clinical and Research Tools taryn.aubrecht@nih.gov Sara Dauber, MBA Strategic Consultant sara.dauber@nih.gov