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In emergency situations, the NIH’s immediate concern is for the health and safety of people and animals in the programs we oversee.  Visit the NIH Extramural Response to Natural Disasters and Other Emergencies web page for biomedical research community resources, including NIH Guide Notices and other information of particular relevance to investigators and their institutions, links to web pages listing NIH’s response to certain major events (past and present); and links to similar web sites from other Federal agencies.

 COVID-19 Funding Notices | Approved Initiative Concepts | Research Opportunity Announcements

All NINDS-related notices of funding opportunities (NOFOs), request for applications (RFAs), program announcements (PAs), and other NIH Guide announcements are listed. Search the Closed Opportunities tab to find expired opportunities. Search the Notices tab to find all Notices.

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Displaying 1 - 10 of 1384 Notices
Notice of Early Expiration of NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08/K23)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-26-030
Thursday, January 22, 2026
Notice Type: NOT
pThe purpose of this notice is to inform potential applicants that effective immediately, the following NOFOs are expired/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-217.html"PAR-24-217/a: NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Clinical Trials Required)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-218.html"PAR-24-2178/a NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Basic Experimental Studies with Humans (BESH) Required)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-219.html"PAR-24-219/a NIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Clinical Scientist Development Awards (K08 - Clinical Trials Not Allowed)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-220.html"PAR-24-220 /aNIH HEAL Initiative PainCare Clinician Training Program (PCTP): Mentored Patient-Oriented Research Career Development award (K23 - Clinical Trial Required)./pp style="margin-left:0in;"No further applications will be accepted under these NOFOs ./ppApplicants should submit their applications to the appropriate parent announcement:/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PA-24-181.html"PA-24-181/a: Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PA-24-183.html"PA-24-183/a: Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Basic Experimental Studies with Humans Required)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PA-24-182.html"PA-24-182/a: Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)/pp style="margin-left:0in;"a href="https://grants.nih.gov/grants/guide/pa-files/PA-24-184.html"PA-24-184/a: Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)/p
Notice of Change: Early Expiration of NINDS Alzheimers Disease-Related Dementias (ADRD) Advanced Postdoctoral Career Transition Award (K99/R00 Independent Clinical Trial Not Allowed)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-26-031
Thursday, January 22, 2026
Notice Type: NOT
pThe purpose of this notice is to inform applicants of the early expiration ofa href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-213.html"PAR-24-213/a NINDS Alzheimers Disease-Related Dementias (ADRD) Advanced Postdoctoral Career Transition Award (K99/R00 Independent Clinical Trial Not Allowed).The last receipt dates fora href="https://grants.nih.gov/grants/guide/pa-files/PAR-24-213.html"PAR-24-213/awill be strongFebruary 12, 2026 for new applications/strongandstrong March 12, 2026 for resubmission applications/strong. The remaining receipt dates scheduled after March 12, 2026, are canceled, and NIH will not acceptapplications under this NOFO beyond that date./ppAfter the expiration of this NOFO, interested applicants are encouraged to submit to the Parent K99/R00 (Independent Clinical Trial Not Allowed), a href="https://grants.nih.gov/grants/guide/pa-files/PA-24-194.html"PA-24-194/a./ppActive K99/R00 awards under this NOFOare not affected by this Notice and are anticipated to continue until the end of their project period, as scheduled. K99/R00 applications submitted to this NOFO for the February and March 2026 receipt dates will still undergo peer review and will be considered for funding in accordance with NIH priorities and the availability of funds./p
Request for Information on Draft Priorities for the Muscular Dystrophy Coordinating Committee's Action Plan
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-022
Thursday, September 4, 2025
Notice Type: NOT
The purpose of this announcement is to request comments and suggestions from the public on draft priorities for the 2025 renewal of the Action Plan for the Muscular Dystrophies. This Action Plan is a ten-year strategic planning document of gaps and opportunities for research and strategies for improving the lives of affected individuals developed by the Muscular Dystrophy Coordinating Committee (MDCC).
Notice of Change: NINDS Participation in PAR-22-213 "Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)"
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-021
Wednesday, May 14, 2025
Notice Type: NOT
Secondary participation
Notice of Change: Expiration of RFA-NS-24-019: HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-024
Thursday, May 8, 2025
Notice Type: NOT
Expiring this NOFO.
Notice of Change: NINDS and Blueprint Participation in PA-25-168: Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-020
Thursday, April 24, 2025
Notice Type: NOT
NINDS and BluePrint will join the NIH Parent T32 NOFO.
Notice of Change: NINDS Interests for PAR-25-143 "Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)"
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-016
Friday, January 17, 2025
Notice Type: NOT
Adding NINDS-specific language.
Notice of Change: Only BESH CT Applications Accepted in PAR-25-050, PAR-24-098, PAR-25-055, PAR-24-096
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-009
Tuesday, January 14, 2025
Notice Type: NOT
This notice is to clarify that onlyBasic Experimental Studies Involving Humans (BESH) clinical trials are withinscope of the above NOFOs (PAR-25-020, PAR-25-055, PAR-24-098, and PAR-24-096). BESH are prospective basic science studies involving human participants (also see NOT-OD-18-212). These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. The types of studies that applicants should submit in response to these NOFOs include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind.
Notice of Change: NINDS Participation in RFA-EY-25-001: BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-012
Tuesday, December 17, 2024
Notice Type: NOT
NINDS is joining for BRAIN.
Notice of Change: Update to Eligibility for PAR-25-234: NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed)
Expiration Date: Monday, January 1, 2029
NOFO Number: NOT-NS-25-007
Wednesday, December 11, 2024
Notice Type: NOT
The purpose of this Notice is to update the Eligible Individuals (Program Director/Principal Investigator section). This NOFO is only open to individuals that are citizens or non-citizen nationals of the United States or have been lawfully admitted for permanent residence to the United States of America.