The Rheumatic Diseases Program of the National Institute of Arthritis and
Musculoskeletal and Skin Diseases (NIAMS), Chronic Disabling Diseases Program,
National Institute of Dental Research (NIDR), Division of Convulsive, Infectious
and Immune Disorders, National Institute of Neurological Disorders and Stroke
(NINDS), Office of Alternative Medicine (OAM), Office of Behavioral and Social
Sciences Research (OBSSR), and the Office of Research on Women"s Health (ORWH)
invite research grant applications (R01) and exploratory/developmental grants
(R21) from interested investigators for tightly focused innovative research
studies related to all aspects of pathogenesis and clinical manifestations of
fibromyalgia syndrome (FMS) and to relationships between FMS and
temporomandibular disorders (TMDs). Improved understanding of the origins and
the biological, neurological and psychosocial mechanisms underlying the clinical
manifestations of fibromyalgia syndrome will have an impact on the development
of more effective diagnostic tests and new therapies for both FMS and related
disorders.
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All NINDS-related notices of funding opportunities (NOFOs), request for applications (RFAs), program announcements (PAs), and other NIH Guide announcements are listed. Search the Closed Opportunities tab to find expired opportunities. Search the Notices tab to find all Notices.
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Expiration Date: Thursday, July 16, 1998 NOFO Number: RFA-AR-98-006 Release Date: Thursday, March 26, 1998 Notice Type: RFA
Expiration Date: Tuesday, March 20, 2001 NOFO Number: PA-98-044 Release Date: Friday, March 20, 1998 Notice Type: PA
The National Institute of Neurological Disorders and Stroke (NINDS) and the
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
encourage investigator-initiated research grant applications to study the
pathogenesis and therapy of the various forms of muscular dystrophy in children
and adults. Responses to this program announcement may include studies in
appropriate animal models or preclinical or clinical studies in patients with
facioscapulohumeral dystrophy (FSH), limb-girdle muscular dystrophy (LGMD),
myotonic dystrophy, congenital muscular dystrophy (CMD), Emery-Dreifuss muscular
dystrophy (EMD), Duchenne muscular dystrophy (DMD), Becker muscular dystrophy
(BMD), or other forms of muscular dystrophy.
Expiration Date: Saturday, June 6, 1998 NOFO Number: RFA-MH-98-009 Release Date: Thursday, March 12, 1998 Notice Type: RFA
This Request for Applications (RFA) solicits grant applications to develop and
implement a procedure for collection of Central Nervous System (CNS) tissues from
HIV infected patients through a standardized autopsy protocol. Applications
responding to this RFA must describe a process for recruitment and selection of
HIV-infected individuals into a protocol that will include regular assessments
of neurological status, assessment of drug use history with verification by
objective measures when possible, regular blood and CSF collection for
virological and serological studies, and implementation of the necessary events
culminating in the collection of CNS tissue at autopsy. Of particular interest
to NIDA is documentation of drug use history and verification by objective
measures when possible. A standardized autopsy protocol, developed during
several workgroups with participation of contributing Institute Program staff and
extramural researchers, has been recommended, and applicants should use this
protocol in their research design.
Expiration Date: Sunday, February 25, 2001 NOFO Number: PAS-98-033 Release Date: Wednesday, February 25, 1998 Notice Type: PAS
The National Institutes of Health (NIH) is committed to investigating the
efficacy of acupuncture for treating or preventing disease and accompanying
symptoms by supporting well-designed, well-executed, randomized clinical trials
(RCT). Before proceeding to a full-scale RCT, pilot clinical studies are often
required. In the present program announcement (PA), the NIH announces its
interest in supporting pilot studies to establish the methodological feasibility
and strengthen the scientific rationale for proceeding to full-scale RCTs on the
use of acupuncture to prevent, manage, or treat various symptoms/disorders. The
emphasis of these pilot trials should be placed on the development of appropriate
study design rather than on attempts to complete an insufficiently powered RCT.
For the purposes of this PA, trials of acupuncture incorporating moxibustion or
herbal medicine will not be considered. Under this PA, applications will be
accepted on a single application receipt date and reviewed by a Special Emphasis
Panel (SEP) administered through the Center for Scientific Review (CSR).
Expiration Date: Friday, February 23, 2001 NOFO Number: PA-98-030 Release Date: Monday, February 23, 1998 Notice Type: PA
The National Institute of Nursing Research (NINR), National Institute on Aging
(NIA), National Institute of Child Health and Human Development (NICHD), National
Institute on Deafness and Other Communication Disorders (NIDCD), and National
Institute of Neurological Disorders and Stroke (NINDS) are interested in
facilitating investigator-initiated research designed to deal with symptoms
associated with chronic neurological conditions including stroke, epilepsy, brain
and spinal cord injury, multiple sclerosis, and Parkinson"s disease. The overall
goals are to manage symptoms effectively, to prevent secondary effects of the
condition when possible, to maximize the health potential, and to improve the
health-related quality of life for patients, caregivers, and families.
Expiration Date: Thursday, May 7, 1998 NOFO Number: RFA-MH-98-017 Release Date: Wednesday, February 11, 1998 Notice Type: RFA
The purpose of this Request for Applications (RFA) is to solicit applications for
innovative research projects that will develop new quantitative methods for
mapping sets of genes that influence susceptibility to complex human diseases.
The specific objectives to be accomplished are: (1) the development of powerful
and flexible statistical methods that will enable researchers to localize and map
multiple disease susceptibility genes, and (2) the implementation of these new,
sophisticated methods in highly efficient and well-documented computer programs
widely disseminated for use by a broad range of biomedical researchers.
Expiration Date: Saturday, April 11, 1998 NOFO Number: RFA-DK-98-006 Release Date: Friday, December 5, 1997 Notice Type: RFA
The purpose of this Request for Applications (RFA) is to solicit applications as
part of an effort to create resources that will facilitate the mapping and
positional cloning of genes in the zebrafish. The specific objectives to be
accomplished are: (1) the generation of a genetic map with a resolution of 0.3
cM or better, (2) the development of Expressed Sequence Tags (ESTs) both from
existing libraries and also from new cDNA libraries from specific developmental
time points and tissues generated under this RFA, and (3) creation of a physical
(radiation hybrid) map of the zebrafish genome.
Expiration Date: Friday, March 20, 1998 NOFO Number: RFA-DK-98-009 Release Date: Friday, November 21, 1997 Notice Type: RFA
The Institutes listed above invite investigator-initiated research grant
applications to study the mechanisms by which hyperglycemia results in the late
complications of diabetes and to apply this information to the development of
interventions to prevent, limit or reverse complications associated with type 1
diabetes. The Request for Applications (RFA) addresses pathogenic mechanisms
common to the spectrum of complications of diabetes, as well as research directed
specifically at diabetic neuropathy and retinopathy, and macrovascular and oral
complications. A complementary RFA (DK-98-001) is focused on mechanisms, genetic
determinants and interventions for diabetic nephropathy. A particular area of
scientific opportunity, which is emphasized in this RFA, is the role of growth
factors in the pathogenesis and/or therapy of complications of diabetes. The
intent of this RFA is to intensify investigator-initiated research, to attract
new investigators to the field and to enhance interdisciplinary approaches to
research in these areas.
Expiration Date: Saturday, April 25, 1998 NOFO Number: RFA-NS-98-001 Release Date: Friday, November 21, 1997 Notice Type: RFA
In response to recent research progress and opportunity, and in recognition of
Congressional interest to intensify and to expand basic and clinical research in
Parkinson"s Disease, the National Institute of Neurological Disorders and Stroke
(NINDS) invites qualified investigators to submit grant applications for the
establishment of NINDS Parkinson"s Disease Research Centers of Excellence. The
purpose of this Request for Applications (RFA) is to encourage additional
research opportunities and discoveries that will lead to improved diagnosis and
treatment of patients with Parkinson"s Disease, based on a better understanding
of the fundamental cause(s) of the disease. It is expected that these Centers
will foster an environment that will enhance the research effectiveness of
investigators in a multi-disciplinary setting, utilizing specialized methods
relevant to the study of Parkinson"s Disease.
Expiration Date: Friday, May 22, 1998 NOFO Number: RFA-OD-98-002 Release Date: Friday, October 24, 1997 Notice Type: RFA
The above named organizations invite applications for a four year
research grant program to test interventions designed to achieve
long-term health behavior change. The health behaviors of
interest-- tobacco use, insufficient exercise, poor diet, and
alcohol abuse--are among the top ten causes for morbidity and
premature mortality. This Request for Applications (RFA) solicits
intervention studies aimed at either comparing alternative theories
related to mechanisms involved in behavior change, or assessing the
utility of a particular theoretical model for changing two or more
health-related behaviors, rather than simply demonstrating the
efficacy of a single behavior change program.