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Clarification Eligibility Applications PAR-13-362 Neurological Sciences Academic Development Award K12)" Notice Number: NOT-NS-14-003 Key Dates Release Date: November 4, 2013 Related Announcements PAR-13-362 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Neurological Sciences Academic Development Award NSADA) K12 award designed support individuals trained pediatric neurology foster careers clinician-scientists. Typically, individuals supported while a residency program. Whereas is anticipated applications generally from accredited medical school, is recognized many accredited medical schools affiliated one more hospitals, that funding residents be managed an affiliated hospital. list eligible organizations PAR-13-362 NSADA K12) includes only Higher Education Institutions." purpose this Notice to inform community a hospital manages funding pediatric neurology residents also eligible be applicant institution this FOA. However, applicant institution must affiliated an accredited medical school the PD/PI the NSADA K12 application must an appointment an appropriate academic department the medical school an appointment the applicant institution. Inquiries Please direct inquiries to: Stephen Korn, Ph.D. Director, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-4188 Email: korns@ninds.nih.gov    

Notice Updates the National Robotics Initiative NRI) Notice Number: NOT-EB-13-005 Key Dates Release Date: October 29, 2013 Related Announcements NOT-EB-14-008 NOT-EB-12-006 Issued National Institutes Health NIH) National Eye Institute NEI) National Institute Aging NIA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Science Foundation NSF) National Aeronautics Space Administration NASA) U.S. Department Agriculture USDA) Purpose Notice updates supersedes previous Guide Notice, NOT-EB-12-006, published the NIH Guide, September 21, 2012. NIH collaborating a multi-agency funding opportunity, National Robotics Initiative NRI) http://www.nsf.gov/funding//pgm_summ.jsp?pims_id=503641), whose goal to accelerate development use robots the United States work beside, cooperatively with, people http://www.nsf.gov/pubs/2014/nsf14500/nsf14500.htm). Innovative robotics research applications emphasizing realization such co-robots acting direct support a human supported multiple agencies the federal government including National Institutes Health NIH), National Science Foundation NSF), National Aeronautics Space Administration NASA), the U.S. Department Agriculture USDA). initiative facilitate development the next generation robotics, particularly co-robotics, encourage existing new communities focus innovative application areas. Collaboration between academic, industry, non-profit other organizations strongly encouraged establish better linkages between fundamental science technology development use.   NIH encourages robotics research technology development enhance health, lengthen life reduce illness disability. Specifically, participating NIH institutes interested targeting solicitation tosupport development assistive robotic technology achieve functional independence humans; improve quality life; assist behavioral therapy personalized care; promote wellness/health. most significant challenges be addressing safety issues, especially applications be used home-based long-term care settings where integration complex systems be required. Additionally, assistive robots need quickly adapt changes the user the environment. Human assistive devices should designed assist healthcare providers as well the individuals needing care. Development robotic applications important NIH because their potential significant impact healthcare the future. Human assistive devices revolutionize healthcare the next 20 years much personal electronics changed our daily lives the past decades. Affordable accessible robotic technology facilitate wellness personalized healthcare. Continual health assessment personalized intervention the potential offset shrinking size the healthcare workforce the growing elderly disabled population. the future, assistive robotics enable people engage all aspects human life endurance dignity. Examples assistive robotic technology development include are limited to: - Homecare long-term personalized care robots - Robotic wellness/health promotion maintenance - Robotic behavioral therapy - Mobility, manipulation, visual, communication cognitive aids - Assistive robotics eliminate health disparities across populations developing appropriate assistive co-robotic technologies, applicants should consider following basic characteristics: effectiveness, affordability, cultural acceptability, accessibility those need them.  Applicants should describe these technologies address healthcare needs the end user healthy individuals, persons disability, or health disparity populations). robotic applications promoted this solicitation for non-operative settings.  NIH still interested supporting robotics surgical health interventions, however, in response solicitation.  Applicants interested this area should send inquiries the NIH program contacts listed below.  Applicants encouraged utilize resources provided NIH Clinical Translational Science Award CTSA) Program conducting proposed research. Award Information Award sizes NIH funded research projects expected range approximately 100,000 250,000 per year direct costs, durations one five years.  award exceed 250,000 per year direct costs. Estimated program budget, number awards average award size duration subject the availability funds.  Determination awards based three criteria: 1) availability funds, 2) program priorities, 3) scientific merit. Subsequent grant administration procedures be accordance the policies the awarding Institute. Application Preparation Submission Instructions Applications submitted response this program announcement/solicitation should prepared submitted accordance the general guidelines contained the NSF Grant Proposal Guide GPG).  Applications must submitted the NSF, to NIH.  complete text the GPG available electronically the NSF Web Site at: http://nsf.gov/publications/pub_summ.jsp?ods_key=gpg. Applicants reminded identify NSF program announcement number the program announcement block the NSF Cover Sheet Proposal the National Science Foundation.  Compliance this announcement critical determining relevant application processing guidelines.  Failure submit information delay processing. Budgetary Information Cost sharing not required applications submitted this funding opportunity. Budgets should include travel funds the PD/PI team members attend annual NRI Principal Investigators' meeting. NIH Process goal this activity to involve multiple agencies using application one review. meet NIH requirements, those applications are identified potential funding participating NIH Institutes Centers ICs), applicant organization be required submit R01 application an NIH-approved format directly the Center Scientific Review http://public.csr.nih.gov/) the NIH.  PDs/PIs invited submit NIH receive further information submission procedures the NIH. NIH application not allowed increase proposed budget change scientific content the application the converted submission the NIH. The summary statement be presented the involved IC's National Advisory Council the second level review. Subsequent the Council review, NIH ICs make funding determinations selected awards be made. Grant administration procedures NIH awardees, including those related New Early Stage Investigators http://grants.nih.gov/grants/new_investigators/) be accordance the policies NIH. Please note applications be submitted review the NSF January 21, 2014. Notification applications selected potential funding the participating NIH ICs be received the beginning April 2014.  converted submission NIH be due April 14, 2014, will an extremely short conversion time.  applicant organization want work closely their Sponsored Programs Office assure timely submission during narrow submission window. earliest project start date be July 1, 2014. Inquiries Written telephone inquiries encouraged.  NIH Program contacts listed below. Please the NSF program announcement names contact information each the participating NSF Directorates http://www.nsf.gov/nri.   Louis Quatrano, Ph. D. Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) Phone:  301-402-4221 Email: quatranl@mail.nih.gov http://www.nichd.nih.gov/    Grace C.Y. Peng, Ph.D., National Institute Biomedical Imaging Bioengineering NIBIB) Phone: 301-451-4778  Email: penggr@mail.nih.gov   http://www.nibib.nih.gov/   Tom Greenwell, Ph.D. National Eye Institute NEI) Phone: 301-451-2020 Email:  greenwellt@nei.nih.gov http://www.nei.nih.gov/ Lyndon Joseph, Ph.D National Institute Aging, NIH, DHHS NIA) Phone: 301-496-6926 Email: Josephlj@nia.nih.gov          http://www.nia.nih.gov/       Roger L. Miller, Ph.D. National Institute Deafness Other Communication Disorders NIDCD) Phone: 301-402-3458 Email:  millerr@nidcd.nih.gov   http://www.nidcd.nih.gov/ Daofen Chen, Ph.D. National Institute Neurological Disorders Stroke NINDS) Phone: 301-496-9964 Email: daofen.chen@nih.gov http://www.ninds.nih.gov/ Paul A. Cotton, PhD, RD, Program Director National Institute Nursing Research NINR) Phone: 301-402-6423 Email: Paul.Cotton@nih.gov     http://www.ninr.nih.gov/       

Notice Correct Anticipated Application Due Date NINDS Exploratory Grant Program Parkinson's Disease Research P20) Notice Number: NOT-NS-14-001 Update: following update relating this announcement been issued: 19, 2014 - Notice NOT-NS-14-033. Notice update information provided. Key Dates Release Date: October 24, 2013 Related Announcements NOT-NS-13-040 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to correct anticipated application due date the NINDS Exploratory Grant Program Parkinson's Disease Research P20).  anticipated application due date be April 2014. other aspects NOT-NS-13-040 remain unchanged. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email: sieberb@ninds.nih.gov  

Notice the Extension the Response Date NINDS's Request Information RFI): Advancing Research Parkinson's Disease 2014 Notice Number: NOT-NS-13-042 Key Dates Release Date: September 26, 2013 Related Announcements NOT-NS-13-035 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice extends expiration date NOT-NS-13-035 quot;Request Information RFI): Advancing Research Parkinson's Disease 2014". Accordingly, responses the RFI be accepted an additional month: Current Expiration Date: September 30, 2013 New Expiration Date: October 31, 2013 other aspects the RFI remain same. RFI responses must submitted electronically http://www.ninds.nih.gov/funding/RFI-PD.htm. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Email: sieberb@ninds.nih.gov

Notice Intent Publish Funding Opportunity Announcement the NINDS Exploratory Grant Program Parkinson's Disease Research P20) Notice Number: NOT-NS-13-040 Update: following update relating this announcement been issued: 19, 2014 - Notice NOT-NS-14-033. Notice update information provided. October 24, 2013 - Notice NOT-NS-14-001. Notice Correct Anticipated Application Due Date. Key Dates Release Date: September 23, 2013   Estimated Publication Date Announcement: November 2013  First Estimated Application Due Date: January 2014  New Date April 2014 per NOT-NS-14-001) Earliest Estimated Award Date: July 2014  Earliest Estimated Start Date: July 2014 Related Announcements None Issued National Institute Neurological Disorders Stroke NINDS) Purpose Parkinson's disease PD) a chronic, progressive movement disorder affects least half million people the United States, well the relatives friends care them. average age onset during sixth decade, although earlier onset also possible, the incidence PD expected increase the population ages. While significant research advances continue, full complexity PD etiology not yet evident. Moreover, currently available treatments primarily symptomatic, neither slow halt disease progression. Challenges posed the inherent complexity PD often best addressed multidisciplinary research teams working tandem surmount obstacles seize opportunities advance knowledge improve treatment. However, development an effective team, identification an optimal strategy collection preliminary data address particular challenge PD require dedicated time resources. Therefore, National Institute Neurological Disorders Stroke NINDS) solicit Exploratory Grant P20) applications proposing planning and initiation collaborative research activities advance PD research. goal this program to formalize collaborative structures establish foundation research discovery necessary address intransigent issues PD research, such successful exploratory studies lead a subsequent application support a collaborative, multidisciplinary NINDS Morris K. Udall Center Excellence P50). foster development innovative research collaborations, FOA provide support new projects, continuation projects have already initiated. Notice being provided allow potential applicants sufficient time develop meaningful collaborations responsive projects.  FOA expected be published Fall 2013 an expected application due date January 2013. Research Initiative Details NINDS Exploratory Grant Program provide support collaborative, multidisciplinary groups plan future application elucidation, disease modification prevention Parkinson's disease. most compelling P20 applications address unifying theme pursue focused, consortium-based strategy develop research approach which near-term, significant progress be made. Collaborative teams include expertise required address critical gaps knowledge are barriers therapeutic translation research findings; collaborations between public private sector encouraged. Related activities include preliminary data generation, pilot feasibility studies other organizational activities necessary prepare full scale NINDS Udall Center application. Proposed pilot studies must defined within application. Proposals include any combination basic, translational clinical components required the planning a subsequent application. Interventional clinical trials not included this FOA. Applicants also expected address significance outcomes PD research treatment should subsequent full-scale Udall Center grant awarded. Successful applicants establish proof-of-concept” experimental framework could generalized organize subsequent research efforts meet specific challenges PD research. Applicants request maximum annual direct costs 300,000 per year, up three years. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email: sieberb@ninds.nih.gov

Notice a Webinar Discuss Changes PAR-13-343 Network Excellence Neuroscience Clinical Trials NeuroNEXT) U01)" Notice Number: NOT-NS-13-041 Key Dates Release Date: September 23, 2013 Related Announcements PAR-13-343 Issued National Institute Neurological Disorders Stroke NINDS) Purpose webinar intended inform academic community the changes be found the revised Network Excellence Neuroscience Clinical Trials NeuroNEXT) U01 funding opportunity announcement PAR-13-343), reissued August 30, 2013. Time be allotted questions answers. NeuroNEXT designed increase efficiency clinical trials, facilitate patient recruitment retention, increase quality neuroscience clinical trials, to enable public-private partnerships. network includes multiple Clinical Sites, Clinical Coordinating Center CCC), one Data Coordinating Center DCC); listing the sites be found the NeuroNEXT website www.neuronext.org). clinical research network provides robust, standardized, accessible infrastructure facilitate rapid development implementation protocols neurological disorders affecting adult and/or pediatric populations. Webinar Information November 22, 2013 12:00PM - 1:00PM EST) Instructions joining webinar: 1. to link join webinar: https://www1.gotomeeting.com 2. will connected audio using computer's microphone speakers VoIP). headset recommended. Or, may select quot;Use Telephone" after joining webinar, using following information: Teleconference number: 1-702-489-0003 Access code: 999-883-025 Audio PIN: Shown after joining Webinar Inquiries Please direct inquiries to: Amanda Sibley, DPhil, MPH National Institute Neurological Disorders Stroke NINDS) Telephone: 301) 496-9135 Email: amanda.sibley@nih.gov Website: www.neuronext.org nbsp;

Request Information RFI) the Action Plan the Muscular Dystrophies Notice Number: NOT-NS-14-039 Key Dates Release Date: August 30, 2013   Response Date: December 20, 2013 Related Announcements None Issued National Institute Neurological Disorders Stroke NINDS) National Heart, Lung, Blood Institute NHLBI) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) Purpose NIH, together the Muscular Dystrophy Coordinating Committee MDCC), leading effort update Action Plan the Muscular Dystrophies, was released 2005.  help inform planning process, NIH the MDCC welcome comments the public regarding accomplishments since Plan’s approval, remaining opportunities, suggestions new research objectives. Background NIH’s mission to seek fundamental knowledge the nature behavior living systems the application that knowledge enhance health, lengthen life, reduce illness disability. National Institute Neurological Disorders Stroke NINDS), National Institute Arthritis Musculoskeletal Skin Diseases NIAMS), Eunice Kennedy Shriver National Institute Child Health Human Development NICHD), the National Heart, Lung, Blood Institute NHLBI) fund majority muscular dystrophy-related research NIH work together coordinate muscular dystrophy research activities across NIH.  muscular dystrophies a group hereditary, progressive degenerative disorders causing weakness the skeletal voluntary muscles.  are different forms muscular dystrophy, differ their age onset, severity, pattern muscles other body systems affected.  Among provisions, Muscular Dystrophy Community Assistance, Research, Education Amendments 2001 MD-CARE Act, Public Law 107-84) established MDCC prompted series activities leading the development the Action Plan the Muscular Dystrophies.  Action Plan, developed input an MDCC Scientific Working Group, includes research objectives five areas: Mechanisms Muscular Dystrophy, Diagnosis Screening Muscular Dystrophy, Therapy Muscular Dystrophy, Living Muscular Dystrophy, Research Infrastructure Needs Muscular Dystrophy.  Through individual collaborative activities researchers, clinicians, stakeholders in  muscular dystrophy community, driven, part, the Action Plan, have significant advances understanding disease mechanisms, development new diagnostic tools reduce diagnostic odyssey affected individuals their families, evolution drug discovery development partnerships have advanced candidate therapeutics, improvements the care quality life affected individuals.  While type muscular dystrophy distinctive, has required disease-appropriate activities, has benefited a shared focus the muscular dystrophy community.  this time, are new challenges gaps require assessment progress a re-focus current needs. Information Requested NIH the MDCC invite muscular dystrophy research, advocacy, family communities provide comments their perspective progress toward objectives the Action Plan, on remaining opportunities.  NIH also welcomes suggestions modifications the existing research objectives, research objectives are longer needed, new objectives should considered the updated Action Plan.  collected comments be reviewed considered the MDCC an MDCC Scientific Working Group develop updated Action Plan.  to Submit Response Responses this RFI must submitted electronically using web-based format at: http://www.ninds.nih.gov/funding/RFI-MuscularDystrophies.htm. Responses be accepted until December 20, 2013.  Responses this RFI voluntary.  Submitted information not considered confidential.  Any personal identifiers be removed responses compiled. request for information planning purposes only should be construed a solicitation as obligation the part the Federal Government. NIH does intend make any awards based responses this RFI to otherwise pay the preparation any information submitted for Government's of such information. NIH use information submitted response this RFI its discretion will provide comments any responder’s submission. However, responses the RFI be reflected future funding opportunity announcements. information provided be analyzed may appear reports. Respondents advised the Government under obligation acknowledge receipt the information received provide feedback respondents respect any information submitted.  proprietary, classified, confidential, sensitive information should included your response. Government reserves right use any non-proprietary technical information any resultant solicitation(s). Inquiries Please direct inquiries to: John D. Porter, Ph.D. Executive Secretary, Muscular Dystrophy Coordinating Committee National Institute Neurological Disorders Stroke Telephone: 301-496-5745 Email: mailto:porterjo@ninds.nih.gov nbsp;

Discontinuation PAR-12-097 Ancillary Studies PREDICT-HD U01)" Notice Number: NOT-NS-13-037 Key Dates Release Date: July 25, 2013 Effective Date:   August 15, 2013 Related Announcements PAR-12-097 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice informs potential applicants NINDS discontinue PAR-12-097  "Ancillary Studies PREDICT-HD U01)". Applications not accepted NINDS this Funding Opportunity Announcement after August 14, 2013 Application Due Date. Inquiries Please direct inquiries to: Margaret Sutherland, Ph.D Program Director, National Institute Neurological Disorders Stroke 6001 Executive Blvd, Bethesda, MD 20892 Telephone: 301-496-5680 Email: sutherlandm@ninds.nih.gov nbsp;

Discontinuation Participation NINDS PA-11-196 Mentored Quantitative Research Development Award K25)" Notice Number: NOT-NS-13-031 Key Dates Release Date: July 18, 2013 Related Announcements PA-11-196 Issued National Institute Neurological Disorders Stroke NINDS) Purpose notice informs potential applicants NINDS discontinue participation PA-11-196 quot;Mentored Quantitative Research Development Award Parent K25)." New applications not accepted NINDS this award after September 7, 2013. Resubmitted A1) applications not accepted after 7, 2014. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Stephen Korn, Ph.D. National Institute Neurological Disorders Stroke Office Training, Career Development, Workforce Diversity 6001 Executive Blvd, Room 2186 Bethesda, MD 20892 Telephone: 301) 496-4188 Email: korns@ninds.nih.gov nbsp;

Request Information RFI): Advancing Research Parkinson's Disease 2014 Notice Number: NOT-NS-13-035 Update: following update relating this announcement been issued: September 26, 2013 - Notice NOT-NS-13-042. Notice the Extension the Response Date. Key Dates Release Date: July 18, 2013 Response Due Date: September 30, 2013 Extended October 31, 2013 per NOT-NS-13-042) Issued National Institute Neurological Disorders Stroke NINDS) Purpose National Institute Neurological Disorders Stroke NINDS), part the National Institutes Health NIH), the primary federal agency responsible funding research Parkinson's Disease PD). January 6-7, 2014, NINDS sponsor public conference assess critical needs related opportunities advancing PD research treatment. purpose this time-sensitive Request Information RFI) to seek comprehensive perspective the most significant challenges highest priorities basic, translational clinical research PD. RFI intended gather information relevant conference planning should be construed a funding opportunity. Information Requested RFI intended solicit broad community perspective scientific opportunities outstanding needs research treatment PD. NINDS invites input stakeholders including not limited researchers academia industry, healthcare professionals, patient advocates advocacy organizations, scientific professional organizations, Federal agencies other interested members the public. Organizations encouraged submit single response reflects views the organization a whole. Responses be used inform 2014 NINDS PD conference. NINDS interested basic, translational clinical PD research, well interdisciplinary approaches span areas. Please provide perspectives the following topics: New and/or ongoing challenges opportunities PD research treatment breakthroughs. highest individual priority PD each the following: basic, translational clinical research; well the impact accomplishment stated priority areas have laboratory-based science, clinical trials, patient well-being public health. Specific elements needed address basic, translational clinical priorities to remove any related obstacles. Examples such elements might include are limited to: enhanced tools, technologies, research resources; novel combinations research team expertise collaboration; bioinformatics resources; infrastructure. to Submit Response ensure consideration, responses must received September 30, 2013 must submitted electronically using web-based format www.ninds.nih.gov/funding/RFI-PD.htm. web format provide confirmation response submission, respondents not receive individualized feedback. Responses this RFI voluntary may submitted anonymously. Please not include any personally identifiable other information you not wish make public. Proprietary, classified, confidential sensitive information should be included your response. Comments submitted be compiled discussion the upcoming January 2014 conference may appear related reports. Any personal identifiers names, e-mail addresses, etc.) be removed responses compiled. RFI for informational planning purposes only should be construed a solicitation as obligation the part the United States US) Government, NIH the NINDS provide support any ideas submitted response it. Please note the US Government, NIH NINDS not pay the preparation any information submitted, for use that information. Inquiries Please direct inquiries to: Beth-Anne Sieber, PhD Program Director, Neurodegeneration National Institute Neurological Disorders Stroke Email: sieberb@ninds.nih.gov