Fundamental Neuroscience Research

A color coded Neuron in C. elegans Hobert Lab
Multicolor atlas of every neuron in C. elegans using NeuroPAL. Eviatar Yemini and Oliver Hobert

The mission of NINDS is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. Research and discovery in fundamental neuroscience (FN) are the foundations of achieving that mission.  A more complete understanding of the development, the structure, and the function of the normal nervous system will benefit the entire neuroscience community.

For well over a century, discoveries in basic neuroscience research have been the basis for our understanding of the nervous system and the foundation for developing treatments for neurological disorders. Insights into fundamental neuroscience (FN) have advanced at an ever-faster pace in the 21st century, with remarkable novel discoveries in areas ranging from subcellular mechanisms of action to whole brain activities. FN generates key insights, drives innovation, and underlies many therapeutic breakthroughs that benefit humanity.


Neurology’s Stake in Foundational Neuroscience Research

Back to Basics: A call for fundamental neuroscience research


A Request for Information (RFI) on Advancing Research in Fundamental Neuroscience

Please consider submitting suggestions and comments via this RFI to help the NINDS best support fundamental neuroscience.

The purpose of this time-sensitive RFI is to solicit public input to the NINDS regarding the challenges and opportunities in fundamental neuroscience research to best understand the normal development, structure, and function of nervous systems.

If so, please include your image with the following information and submit to:

  • Your name
  • Description of image
  • Credit of image

NOTE: Image should be in a jpg, jpeg, gif, png or pdf format.


Resources and Tools:

Animal Models

Resources available to neuroscience researchers interested in utilizing animals as models for nervous system function.

Gene Expression

The resources listed below are for gene expression-related information relevant to neuroscience research.

Strategic Plan

NINDS supports and performs a broad array of rigorous and important neuroscience research from fundamental studies of basic nervous system function to studies to improve treatments and prevent neurological disorders.

NINDS Funding Strategy

Current NINDS funding guidelines and payline.

NIH BRAIN Initiative

The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is aimed at revolutionizing our understanding of the human brain.

Building Up The Nerve

Neuroscience trainees are taken through the life cycle of a grant from idea to award at NINDS with the people who make it happen.

Find an NINDS Program Director

Please reach out to individual Program Directors or Program Managers for more information about specific opportunities or visit Find Your Program Director to learn more.