NANDSC Fundamental Neuroscience Working Group


The mission of NINDS is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease for all people. Research on the development, structure, and function of the normal nervous system, or fundamental neuroscience (FN), is the foundation for achieving that mission. To address this important component of the research portfolio, NINDS convened a Fundamental Neuroscience Working Group (FNWG) of the National Advisory Neurological Disorders and Stroke (NANDS) Council to hold a series of meetings to discuss key issues and prepare a report to the NANDS Council with recommendations to inform NINDS approaches and plans to support and foster FN research.

Charge of the Committee

This new NANDS Working Group will provide scientific guidance via NANDS Council to NINDS on how best to advance FN research.

Consistent with this charge, this NANDS-WG will:

  • Look to the future of FN by identifying critical gaps, key unanswered questions and new opportunities in FN research.
  • Evaluate the effectiveness and potential of current NINDS programs to support the breadth of FN research.
  • Propose and prioritize concepts and strategies with the potential to enhance the overall impact of NINDS FN research over the next 5-10 years.

Process, Deliverables, and Timeframe

This working group of the NANDS Council will:

  • Consider specific recommendations to optimize or enhance current NINDS programs in support of the FN research mission.
  • Identify opportunities that NINDS could take to facilitate innovation and enable discoveries that are not currently addressed in FN.
  • Evaluate how the NINDS might support the development, refinement, dissemination and broad use of next generation technologies, approaches, or resources to open new areas of exploration.
  • Present its final report of findings stemming from the above charge to the full NANDS Council.

Working Group Members

Yishi Jin, Ph.D. (Co-Chair)
University of California, San Diego

Timothy Ryan, Ph.D. (Co-Chair)
Weill Cornell Medical College
Howard Hughes Medical Institute

Bruce Bean, Ph.D.
Harvard Medical School

David Clapham, M.D., Ph.D.
Janelia Research Campus, Howard Hughes Medical Institute

Marc Freeman, Ph.D.
Vollum Institute, Oregon Health & Science University

José E. García Arrarás, Ph.D.
University of Puerto Rico, Río Piedras Campus

Alicia Dione Guemez-Gamboa, Ph.D.
Northwestern University

Shantá Hinton, Ph.D.
William & Mary

Oliver Hobert, Ph.D.
Columbia University
Howard Hughes Medical Institute

Sarah Kucenas, Ph.D.
University of Virginia      

Rejji Kuruvilla, Ph.D.
Johns Hopkins University

Wendy Macklin, Ph.D.
University of Colorado

Kelsey Martin, M.D., Ph.D.
Simons Foundation 

Linda Richards, AO, FAA, FAHMS, Ph.D.
Washington University

Amita Sehgal, Ph.D.
University of Pennsylvania
Howard Hughes Medical Institute

Weiwei Wang, Ph.D.
University of Texas Southwestern Medical Center



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