The purpose of this biobehavioral pain research program announcement
is to inform the scientific community of the interests of the various
institutes at the National Institutes of Health (NIH) and to
stimulate and foster a wide range of basic and clinical studies on
pain as they relate to the missions of these Institutes.
Applications are encouraged to study individual differences in pain
responses which may be due to factors such as genetic differences,
endocrine activity, neural activity, immune function, psychological
state, disability state, age, gender, and cultural background.
Research is also needed in areas such as understanding the
neuroanatomical pathways and the neurophysiological mechanisms in
pain. The pain experience needs to be examined at all levels of
research including the gene, molecule, cell, organ, and individual
with the goal of developing biobehavioral interventions to manage or
prevent pain.
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Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-056 Release Date: Friday, April 28, 1995 Notice Type: PA
Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-049 Release Date: Friday, April 28, 1995 Notice Type: PA
The Mentored Research Scientist Development Award (MRSDA) is for
research scientists who need an additional period of sponsored
research experience as a way to gain expertise in a research area new
to the candidate or in an area that would demonstrably enhance the
candidate's scientific career. It is expected that following this
experience, the candidate will be able to pursue an independent and
productive research career.
Expiration Date: Tuesday, April 28, 1998 NOFO Number: PA-95-053 Release Date: Friday, April 28, 1995 Notice Type: PA
The purpose of the Mentored Clinical Scientist Development Award
MCSDA is to support the development of outstanding clinician research
scientists. This mechanism provides specialized study for clinically
trained professionals who are committed to a career in research and
have the potential to develop into independent investigators. The
award supports a three, four, or five year period of supervised
research experience that may integrate didactic studies with
laboratory or clinically-based research. The proposed research
should have both intrinsic research importance and be a suitable
vehicle for learning the methodology, theories, and
conceptualizations necessary for a well trained independent
researcher.
Expiration Date: Tuesday, April 14, 1998 NOFO Number: PAR-95-047 Release Date: Friday, April 14, 1995 Notice Type: PAR
The Division of AIDS (DAIDS), National Institute of Allergy and
Infectious Diseases (NIAID), solicits applications on the discovery,
preclinical efficacy evaluation, and development of novel agents and
strategies that suppress HIV replication, interfere with disease
progression, and ameliorate the consequences of infection.
Responsive applications will involve creative and original research
that emphasizes under- exploited facets of HIV infection. The
National Institute of Mental Health (NIMH) solicits grant
applications directed toward identifying the mechanisms underlying
the cognitive and behavioral changes associated with HIV infection.
The National Institute of Neurological Disorders and Stroke (NINDS)
solicits grant applications directed toward studies on the
neurological complications of HIV infection. Both institutes seek
grant applications investigating potential CNS-targeted drug
therapies that prevent or alleviate CNS dysfunction. Under this PA,
applications in the following areas are not being solicited: (1)
anti-viral agents and therapeutic strategies currently under intense
investigation, (2) clinical studies, (3) studies of AIDS- related
malignancies, and (4) studies of AIDS-associated opportunistic
pathogens. Support under this PA will be provided to inter-related
research consortia that include the private sector as one of its
Group components. Applications funded in response to this PA will
become part of the NCDDG-HIV.
Expiration Date: Tuesday, January 13, 1998 NOFO Number: PA-95-017 Release Date: Friday, January 13, 1995 Notice Type: PA
The National Institute of Neurological Disorders and Stroke (NINDS)
and the National Center for Medical Rehabilitative Research (NCMRR)
of the National Institute of Child Health and Human Development
(NICHD) announce the issuance of a program announcement to notify the
scientific community of their interest in the submission of research
grant applications concerning syringomyelia.
Expiration Date: Tuesday, December 23, 1997 NOFO Number: PA-95-014 Release Date: Friday, December 23, 1994 Notice Type: PA
Sleep disturbances affect a wide range of age groups and practically
every segment of society is profoundly affected by the absence of
healthful patterns of sleep and wakefulness. It is now apparent that
sleep disorders, disturbances of sleep, and sleep deprivation are
major public health concerns. Recent estimates suggest that as many
as 40 million people may suffer from chronic or intermittent
disorders of sleep. Many of these people remain undiagnosed and
untreated, the consequences of which include reduced productivity,
lowered cognitive performance, increased likelihood of accidents,
higher risk of morbidity and mortality and decreased quality of life.
Expiration Date: Wednesday, February 15, 1995 NOFO Number: RFA-HD-95-005 Release Date: Friday, October 21, 1994 Notice Type: RFA
The Human Learning and Behavior Branch (HLB) of the Center for
Research for Mothers and Children (CRMC) of the National Institute of
Child Health and Human Development (NICHD) and the Developmental
Neurology Branch (DNB) of the Division of Convulsive, Developmental,
and Neuromuscular Disorders (DCDND) of the National Institute of
Neurological Disorders and Stroke (NINDS) invite research grant
applications to develop new knowledge in the areas of definition,
classification, epidemiology, prevention (and preventive strategies),
early intervention, etiology, diagnosis, and treatment of children
who display learning disabilities (LD) in component oral language
abilities (phonology, morphology, semantics, syntax, pragmatics),
reading (word attack skills, word recognition skills, reading
comprehension), written expression abilities (spelling, composition),
and mathematics (basic calculation skills, mathematical reasoning),
and combinations and relationships among them (e.g., combined
deficits in phonology, word attack skills, spelling behavior and
mathematics). An emphasis should also be placed on identifying the
distinctions and interrelationships (comorbidities) between well
defined types of learning disabilities and other well defined
disorders to include disorders of attention, oppositional/conduct
disorders, genetic disorders affecting learning (e.g., Fragile X
syndrome, Asperger"s syndrome, etc.). In addition, of significant
interest are longitudinal studies of treatment effectiveness with
children with LD who are well defined in terms of age, gender,
ethnicity, SES, primary LD, comorbid LD, severity of disability,
intensity and duration of any previous intervention(s), familial
and/or genetic findings, intellectual status, cognitive-linguistic
status, neuropsychological status, neurophysiological status,
educational status, and social/behavioral competencies.
Expiration Date: Saturday, November 19, 1994 NOFO Number: RFA-DK-94-023 Release Date: Friday, August 12, 1994 Notice Type: RFA
This request for applications (RFA) is designed to encourage research
grant applications focusing on mechanisms (primarily molecular and
genetic mechanisms) that underlie nutrient modulation of cellular
repair processes and maintenance of cellular integrity. Research
should be aimed at the normal processes involved in the effects of
specific nutrients or their metabolites on cellular, genetic, and
metabolic functions, as well as elucidation of defective mechanisms.
This initiative should offer unique opportunities afforded by the basic
sciences and new technologies (e.g., molecular biology, NMR, ESR, PET)
to enrich nutrition science. Nutrition science supported by the
National Institutes of Health (NIH) includes studies designed to assess
the consequences of food or nutrient intake, utilization in the intact
organism, and the metabolic and behavioral mechanisms involved.
Further support is needed for studies of nutrient variables at the
cellular and subcellular levels; elucidation of the metabolic functions
of nutrients in both animal models and humans; examination of
genetic-nutrient-environmental interactions; and ultimately, studies of
the role of diet in the maintenance of health, and the prevention and
treatment of disease.
Expiration Date: Tuesday, July 29, 1997 NOFO Number: PA-94-089 Release Date: Friday, July 29, 1994 Notice Type: PA
The National Institute on Aging (NIA), National Institute on Deafness
and Other Communication Disorders (NIDCD), National Institute of
Neurological Disorders and Stroke (NINDS), and National Aeronautics and
Space Administration (NASA) announce a continuing interest in
supporting ground-based studies of sensorimotor adaptation and
multisensory integration focusing on such functions as posture, gait,
and other limb and body spatially directed movements, in health, in
disease, and in special gravito-inertial environments.
Expiration Date: Tuesday, February 18, 1997 NOFO Number: PA-94-040 Release Date: Friday, February 18, 1994 Notice Type: PA
The National Institute of Neurological Disorders and Stroke (NINDS)
and the National Institute of Arthritis and Musculoskeletal and Skin
Diseases (NIAMS) encourage the submission of research grant
applications to investigate the potential for gene therapy in
Duchenne muscular dystrophy. Responses to this program announcement
may include studies in appropriate animal models of gene replacement
using viral vectors, myoblast transfer, or other means of dystrophin
enhancement.