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Technical Assistance the Development High Throughput Screening HTS) Assay Notice Number: NOT-MH-13-011 Key Dates Release Date: January 16, 2013 Related Announcements PAR-12-058 PAR-12-059 Issued National Institute Mental Health NIMH) National Cancer Institute NCI) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Diabetes Digestive Kidney Diseases NIDDK) National Institute Drug Abuse NIDA) National Institute General Medical Sciences NIGMS) National Institute Neurological Disorders Stroke NINDS) Purpose purpose this notice to facilitate access researchers a screening laboratory develop High Throughput Screening HTS) assay thereby submit grant application PAR-12-058 R01) PAR-12-059 R21). HTS Assay Development Assistance screening laboratory e.g., Academic Screening Facilities Directory, http://www.slas.org/screeningFacilities/facilityList.cfm) provide advice such identification selection commercial HTS assay reagents, suitable HTS assay format readout. addition, screening laboratory be able provide assistance adapting assays an HTS format e.g., 1536-well 384-well microplate) performing pilot screen a small library compounds e.g., Library Pharmacologically Active Compounds LOPAC) collection, NIH Clinical Collection, etc.) generate sufficient preliminary assay data support grant application submission. Further, researchers might seek advice the screening laboratory orthogonal assays validate screening hits, advice chemical improvement the initial hits via structure-activity relationship SAR) study. technical resources HTS assay development include online comprehensive guidebook Assay Guidance Manual http://www.ncbi.nlm.nih.gov/books/NBK53196/), HTS assay protocols deposited PubChem BioAssay data base http://www.ncbi.nlm.nih.gov/sites/entrez?db=pcassay), ASSAY Drug Development Technologies, peer-reviewed bimonthly journal, the Journal Biomolecular Screening. Inquiries Inquiries regarding Notice be directed to: Yong Yao, Ph.D. National Institute Mental Health NIMH) Telephone: nbsp;(301) 443-6102 Email: nbsp;yyao@mail.nih.gov

Notice Intent Publish Funding Opportunity Announcement Countermeasures Against Chemical Threats CounterACT) Cooperative Research Projects U01) Notice Number: NOT-NS-13-004 Key Dates Release Date: December 20, 2012 Estimated Publication Date Announcement: 1, 2013  First Estimated Application Due Date: September 16, 2013   Earliest Estimated Award Date: July 1, 2014  Earliest Estimated Start Date: July 1, 2014 Issued National Institute Neurological Disorders Stroke NINDS) Purpose National Institute Neurological Disorders Stroke NINDS), intends re-issue Program Announcement Special Review Considerations PAR) solicit applications ldquo;Countermeasures Against Chemical Threats CounterACT) Cooperative Research Projects U01)”. goal this initiative to provide support translational research develop therapeutics reducing mortality morbidity caused acute exposures chemical threat agents. Chemical threats toxic chemicals could used a terrorist attack accidentally released industrial production, storage shipping.  scope the research supported within milestone-driven translational program includes target candidate identification characterization, through candidate optimization demonstration in vivo efficacy, through Investigational New Drug IND) submission.   www.ninds.nih.gov/counteract a description the CounterACT program.  Notice being provided allow potential applicants sufficient time develop meaningful collaborations competitive research programs.  FOA expected be published Spring 2013 an expected application due date September 2013. FOA utilize U01 activity code. Details the planned FOA provided below. Research Initiative Details Notice encourages collaborative multidisciplinary investigations, combining expertise toxicology drug discovery development, discover develop new improved therapeutics treating victims chemical exposures. CounterACT research program utilize Research Project - Cooperative Agreements U01) support Research Projects up 5 years translational research.  research project must establish milestones include discrete quantitative goals create or no-go decision points the project.  Chemical threats be covered include chemical warfare agents e.g. sarin, VX), Toxic Industrial Chemicals e.g. phosgene, sulfur dioxide) others. Please contact NIH Program Director below discuss chemical threats be covered.  NIH intends commit approximately 2-3 million per year Fiscal Years 2014, 2015, 2016 fund new and/or competing renewal U01 awards.  Since nature scope the proposed research vary application application, is anticipated the size duration each award also vary. total amount awarded the number awards depend the number, quality, duration, costs the applications received.  is anticipated several NIH Institutes, including National Eye Institute NEI), National Institute Allergy Infectious Diseases NIAID), National Institute Arthritis Musculoskeletal Skin Diseases NIAMS), Eunice Kennedy Shriver National Institute Child Health Human Development NICHD), National Institute Environmental Health Sciences NIEHS), the National Institute General Medical Sciences NIGMS), also participate this funding opportunity announcement.  APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: David A. Jett, Ph.D. Program Director, NIH CounterACT Research National Institutes Health, NINDS 6001 Executive Blvd. NSC, Room 2177, MSC 9527 Bethesda, MD 20892-9527 Telephone: 301-496-6035 Fax: 301-402-1501 Email: jettd@ninds.nih.gov

Notice Intent Publish Funding Opportunity Announcement Countermeasures Against Chemical Threats CounterACT) Research Centers Excellence U54) Notice Number: NOT-NS-13-005 Key Dates Release Date: December 20, 2012 Estimated Publication Date Announcement: 1, 2013  First Estimated Application Due Date: September 16, 2013   Earliest Estimated Award Date: July 1, 2014  Earliest Estimated Start Date: July 1, 2014 Issued National Institute Neurological Disorders Stroke NINDS) Purpose National Institute Neurological Disorders Stroke NINDS), intends re-issue Program Announcement Special Review Considerations PAR) solicit applications ldquo;Countermeasures Against Chemical Threats CounterACT) Research Centers Excellence U54)”. goal this initiative to provide support translational research develop therapeutics reducing mortality morbidity caused acute exposures chemical threat agents. Chemical threats toxic chemicals could used a terrorist attack accidentally released industrial production, storage shipping.  scope the research supported within milestone-driven translational program includes target candidate identification characterization, through candidate optimization demonstration in vivo efficacy, through Investigational New Drug IND) submission.  www.ninds.nih.gov/counteract a description the CounterACT program.  Notice being provided allow potential applicants sufficient time develop meaningful collaborations competitive research programs.  FOA expected be published Spring 2013 an expected receipt date September 2013. FOA utilize U54 activity code. Details the planned FOA provided below. Research Initiative Details Notice encourages collaborative multidisciplinary investigations, combining expertise toxicology drug discovery development, discover develop new improved therapeutics treating victims chemical exposures. CounterACT research program utilize Specialized Center Cooperative Agreements U54) support Research Centers Excellence up 5 years translational research.  Research Center must establish milestones include discrete quantitative goals create or no-go decision points the project.   Each Center include several individual research projects scientific administrative cores create interdisciplinary synergistic multifaceted research approach, centered a central common goal.  Chemical threats be covered include chemical warfare agents e.g. sarin, VX), Toxic Industrial Chemicals e.g. phosgene, sulfur dioxide) others.  Please contact NIH Program Director below discuss chemical threats be covered.    The NIH intends commit approximately 3-4 million per year Fiscal Years 2014, 2015, 2016 fund new and/or competing renewal U54 awards.  Since nature scope the proposed research vary application application, is anticipated the size duration each award also vary. total amount awarded the number awards depend the number, quality, duration, costs the applications received.  is anticipated several NIH Institutes, including National Eye Institute NEI), National Institute Allergy Infectious Diseases NIAID), National Institute Arthritis Musculoskeletal Skin Diseases NIAMS), Eunice Kennedy Shriver National Institute Child Health Human Development NICHD), National Institute Environmental Health Sciences NIEHS), the National Institute General Medical Sciences NIGMS), also participate this funding opportunity announcement.  APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: David A. Jett, Ph.D. Program Director, NIH CounterACT Research National Institutes Health, NINDS 6001 Executive Blvd. NSC, Room 2177, MSC 9527 Bethesda, MD 20892-9527 Telephone: 301-496-6035 Fax: 301-402-1501 Email: jettd@ninds.nih.gov

Notice Intent Publish Funding Opportunity Announcement FOA) Dissemination Implementation Research Health R01) Notice Number: NOT-MH-13-009 Key Dates Release Date: December 20, 2012 Estimated Publication Date Announcement: January 8, 2013  First Estimated Application Due Date: February 5, 20213  Earliest Estimated Award Date: September 2013  Earliest Estimated Start Date: September 2013  Related Announcements PAR-10-038 Issued National Institute Mental Health NIMH) National Cancer Institute NCI) National Center Complementary Alternative Medicine NCCAM) National Heart, Lung, Blood Institute NHLBI) National Human Genome Research Institute NHGRI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Allergy Infectious Diseases NIAID) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Diabetes Digestive Kidney Diseases NIDDK) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) Office Behavioral Social Sciences Research OBSSR) Purpose purpose this Notice to inform potential applicants the National Institute Mental Health, along the participating Institutes listed above, intends reissue PAR-10-038 quot;Dissemination Implementation Research Health R01)," the companion FOAs, will expire January 8, 2013. FOA utilize Research Project Grant R01) activity code. Details the planned FOA provided below. Research Initiative Details funding opportunity encourage research grant applications will identify, develop, evaluate refine effective efficient methods, systems, infrastructures, strategies disseminate implement research-tested health behavior change interventions, evidence-based prevention, early detection, diagnostic, treatment management, quality life improvement services, data monitoring surveillance reporting tools public health clinical practice settings focus patient outcomes. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Inquiries regarding Notice be directed to: David Chambers, D.Phil. National Institute Mental Health NIMH) Telephone: 301-443-3747 Email:  dchamber@mail.nih.gov

Request Information RFI): Curing Epilepsies 2013 - Updating Epilepsy Research Benchmarks Notice Number: NOT-NS-13-003 Key Dates Release Date: November 30, 2012 Responses due by: January 31, 2013 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Request Information RFI) to seek broad input the most important new ongoing challenges opportunities epilepsy research.  Background Since 2000, NINDS has worked the epilepsy community identify priorities research. 2000 2007, NINDS sponsored Curing Epilepsy conferences partnership nongovernmental organizations other Federal agencies assess state epilepsy research identify needs new directions. conferences led the development subsequent revision the Epilepsy Research Benchmarks, series goals research toward cures the epilepsies, defined no seizures, side effects, the prevention epilepsy those risk. 2007 Benchmarks encompass range basic, translational, clinical research priorities focused understanding causes epilepsy, identifying strategies preventing epileptogenesis, developing improving epilepsy treatments, understanding treating comorbid conditions affecting people epilepsy, understanding ultimately preventing sudden unexpected death epilepsy SUDEP).   Benchmarks meant engage entire epilepsy community advancing research, including NIH, NIH grantees other researchers, epilepsy professional organizations, the epilepsy patient community. NINDS particular considers Benchmarks planning new investments epilepsy research has also worked epilepsy researchers serve Benchmarks Stewards track promote progress.  April 17-19, 2013, NINDS sponsor third public conference, quot;Curing Epilepsies 2013: Pathways Forward," reassess state epilepsy research. conference include scientific sessions major topics the field will culminate a discussion possible updates the Epilepsy Research Benchmarks. help inform discussions, Epilepsy Benchmarks Stewards prepared progress report summarizing research advances since 2007, well their views opportunities challenges future research. progress report available the NINDS website at: http://www.ninds.nih.gov/research/epilepsyweb/benchmarks_2007-2012progr…. Information Requested request information intended provide broader perspective progress in epilepsy research on scientific opportunities the years come. NINDS invites input epilepsy researchers academia industry, healthcare professionals, patient advocates advocacy organizations, scientific professional organizations, Federal agencies, other interested members the public. Organizations strongly encouraged submit single response reflects views the organization a whole. Please provide perspectives the following topics.               most important advances basic, translational, clinical epilepsy research since 2007. New ongoing challenges opportunities epilepsy research. role Epilepsy Research Benchmarks played, could play, terms promoting awareness shared priorities stimulating progress. to Submit Response assure consideration, responses must received January 31, 2013, should submitted electronically using web-based form www.ninds.nih.gov/2013epilepsiesRFI. web form provide confirmation response submission, respondents not receive individualized feedback. Responses this RFI voluntary may submitted anonymously.  Please not include any personally identifiable other information you not wish make public.  Proprietary, classified, confidential, sensitive information should be included your response.  Comments submitted be compiled discussion the upcoming conference, Curing Epilepsies 2013: Pathways Forward, may appear various reports.  Any personal identifiers personal names, email addresses, etc.) be removed responses compiled.  Request Information RFI) for informational planning purposes only is a solicitation applications an obligation the part the United States U.S.) Government provide support any ideas identified response it.  Please note the U.S. Government not pay the preparation any information submitted, for use that information. Inquiries Please direct inquiries to: Cara B. A. Long, Ph.D. Office Science Policy Planning National Institute Neurological Disorders Stroke National Institutes Health Phone: 301-496-9172 Email: cara.long@nih.gov

Clarification Budget Instructions RFA-HD-13-004 Centers Collaborative Research Fragile X U01) Notice Number: NOT-HD-12-034 Key Dates Release Date: November 16, 2012 Related Announcements RFA-HD-13-004 nbsp; Issued Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to clarify budget instructions RFA-HD-13-004 quot;Centers Collaborative Research Fragile X U01)". instructions budgets each Center up linked U01 awards) exceed 1.3 million TOTAL costs per year should read 1.3 million DIRECT costs per year. Section II. Award Information - Current Language Individual linked U01 application budgets should reflect actual needs the proposed projects.  Budgets each Center up linked U01 awards) not exceed 1.3 million total costs per year. Section II. Award Information - Revised Language Individual linked U01 application budgets should reflect actual needs the proposed projects.  Budgets each Center up linked U01 awards) not exceed 1.3 million direct costs per year. other aspects this FOA remain same.    Inquiries Please direct inquiries to: Tiina K. Urv, PhD Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) Telephone 301-402-7015 Email: urvtiin@mail.nih.gov   

Notice Change Eligibility Foreign Institutions RFA-LM-12-002 Basic social behavioral research culture, health, wellbeing R24) Notice Number: NOT-LM-13-001 Key Dates Release Date: October 24, 2012 Related Announcements RFA-LM-12-002 Issued National Cancer Institute NCI) National Eye Institute NEI) National Heart, Lung, Blood Institute NHLBI) National Human Genome Research Institute NHGRI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Allergy Infectious Diseases NIAID) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) National Institute General Medical Sciences NIGMS) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Institute Minority Health Health Disparities NIMHD) National Library Medicine NLM) Fogarty International Center FIC) National Center Complementary Alternative Medicine NCCAM) National Center Advancing Translational Sciences NCATS) Division Program Coordination, Planning Strategic Initiatives, Office Research Infrastructure Programs ORIP) Office Behavioral Social Sciences Research OBSSR) Office Dietary Supplements ODS) Office Disease Prevention ODP) Office Research Women’s Health ORWH) Purpose National Library Medicine NLM) expanding institutional eligibility RFA-LM-12-002, quot;Basic social behavioral research culture, health, wellbeing R24)" include Non-domestic non-U.S.) Entities Foreign Institutions), Non-domestic non-U.S.) components U.S. Organizations, Foreign Components, defined the NIH Grants Policy Statement. Foreign Institutions now eligible apply RFA-LM-12-002 indicated below. Section III. 1. Eligible Organizations CURRENTLY READS Foreign Institutions Non-domestic non-U.S.) Entities Foreign Institutions) not eligible apply. Non-domestic non-U.S.) components U.S. Organizations not eligible apply. Foreign components, defined , the NIH Grants Policy Statement, not allowed. Section III.1 Eligible Organizations CHANGED READ Foreign Institutions Non-domestic non-U.S.) Entities Foreign Institutions) eligible apply. Non-domestic non-U.S.) components U.S. Organizations eligible apply. Foreign components, defined the NIH Grants Policy Statement, allowed. line this change the FOA include foreign eligibility, Additional Review Consideration added Section V. Application Review Information RFA-LM-12-002, follows: Section V. 1. Criteria CURRENTLY READS Applications Foreign Organizations Applicable. Section V. 1. Criteria CHANGED READ Applications Foreign Organizations Reviewers assess whether project presents special opportunities furthering research programs through use unusual talent, resources, populations, environmental conditions exist other countries either not readily available the United States augment existing U.S. resources. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Alan VanBiervliet, PhD OppNet RFA Leader Division Extramural Programs National Library Medicine NLM) 6705 Rockledge Drive, Suite 301 Bethesda, MD 20892-7968 301-594-1297 vanbiervlietag@mail.nih.gov www.nlm.nih.gov/ep William N. Elwood, PhD OppNet Facilitator Office Behavioral Social Sciences Research National Institutes Health 31 Center Drive, Suite B1C19, MSC2027 Bethesda, MD  20892-2027 301-402-0116 William.elwood@nih.gov http://oppnet.nih.gov

Participation NINDS RFA-AG-13-011, Paul B. Beeson Clinical Scientist Development Award Aging, K08) Notice Number: NOT-NS-13-001 Key Dates Release Date: October 19, 2012 Related Announcements RFA-AG-13-011 NOT-NS-13-002 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to inform potential applicants the NINDS announces participation, effective immediately, RFA-AG-13-011, Paul B. Beeson Clinical Scientist Development Award Aging K08). RFA-AG-13-011 changed the following ways. Part 1. Overview Information - Components Participating Organizations Components Participating Organizations section RFA-AG-13-011 been revised include NINDS: National Institute Aging NIA) National Institute Neurological Disorders Stroke NINDS) Part 1. Overview Information - Catalog Federal Domestic Assistance CFDA) Number Catalog Federal Domestic Assistance CFDA) Number section been revised include NINDS CFDA number: 93.853.   Section II. Award Information - Funds Available Anticipated Number Awards NINDS intends commit to 400,000 support total up two Beeson Career Development Awards Aging applications submitted response RFA-AG-13-011, and/or companion application K23 applications, RFA-AG-13-012, contingent upon NIH appropriations the receipt a sufficient number meritorious applications research projects fall within NINDS mission. Section VII. Agency Contacts Agency Contacts section been revised reflect inclusion NINDS this program. Scientific/Research Contact(s) Stephen Korn, Ph.D. Chief, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke, NIH email: korns@ninds.nih.gov Financial/Grants Management Contact(s) Tijuanna DeCoster, MPA  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-9231 Email: decostert@ninds.nih.gov other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Scientific/Research Contact(s) Stephen Korn, Ph.D. Chief, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke, NIH email: korns@ninds.nih.gov Financial/Grants Management Contact(s) Tijuanna DeCoster, MPA  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-9231 Email: decostert@ninds.nih.gov   

Participation NINDS RFA-AG-13-012, Paul B. Beeson Patient-Oriented Research Career Development Award Aging K23) Notice Number: NOT-NS-13-002 Key Dates Release Date: October 19, 2012 Related Announcements RFA-AG-13-012 NOT-NS-13-001 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to inform potential applicants the NINDS announces participation, effective immediately, RFA-AG-13-012, Paul B. Beeson Patient-Oriented Research Career Development Award Aging K23). RFA-AG-13-012 changed the following ways. Part 1. Overview Information - Components Participating Organizations Components Participating Organizations section RFA-AG-13-012 been revised include NINDS: National Institute Aging NIA) National Institute Neurological Disorders Stroke NINDS) Part 1. Overview Information - Catalog Federal Domestic Assistance CFDA) Number Catalog Federal Domestic Assistance CFDA) Number been revised include NINDS CFDA number: 93.853. Section II. Award Information - Funds Available Anticipated Number Awards NINDS intends commit to 400,000 support total up two Beeson Career Development Awards Aging applications submitted response RFA-AG-13-012, and/or companion application K08 applications, RFA-AG-13-011, contingent upon NIH appropriations the receipt a sufficient number meritorious applications research projects fall within NINDS mission. Section VII. Agency Contacts Agency Contacts section been revised reflect inclusion NINDS this program. Scientific/Research Contact(s) Stephen Korn, Ph.D. Chief, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke, NIH email: korns@ninds.nih.gov Financial/Grants Management Contact(s) Tijuanna DeCoster, MPA  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-9231 Email: decostert@ninds.nih.gov other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Scientific/Research Contact(s) Stephen Korn, Ph.D. Chief, Office Training, Career Development Workforce Diversity National Institute Neurological Disorders Stroke, NIH email: korns@ninds.nih.gov Financial/Grants Management Contact(s) Tijuanna DeCoster, MPA  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-9231 Email: decostert@ninds.nih.gov

Notice Updates the National Robotics Initiative NRI) Notice Number: NOT-EB-12-006 Update: following update relating this announcement been issued: October 29, 2013 - Notice NOT-EB-13-005. Notice Updates the National Robotics Initiative NRI). Key Dates Release Date: September 21, 2012 Issued National Institutes Health NIH) National Institute Aging NIA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Center Advancing Translational Sciences NCATS) National Science Foundation NSF) National Aeronautics Space Administration NASA) U.S. Department Agriculture USDA) Purpose Notice updates supersedes previous Guide Notice,NOT-EB-11-006, published the NIH Guide, June 24, 2011. NIH collaborating a multi-agency funding opportunity, National Robotics Initiative NRI) http://www.nsf.gov/nri), whose goal to accelerate development use robots the United States work beside, cooperatively with, people http://www.nsf.gov/publications/pub_summ.jsp?WT.z_pims_id=503641&ods_ke…; Innovative robotics research applications emphasizing realization such co-robots acting direct support a human supported multiple agencies the federal government including National Institutes Health NIH), National Science Foundation NSF), National Aeronautics Space Administration NASA), the U.S. Department Agriculture USDA). initiative facilitate development the next generation robotics, particularly co-robotics, encourage existing new communities focus innovative application areas. Collaboration between academic, industry, non-profit other organizations strongly encouraged establish better linkages between fundamental science technology development use.  NIH areas interest include, are limited to, robotics home care; personalized care special needs populations robotic wellness/health promotion; robot-assisted recovery; rehabilitation behavioral therapy; surgical interventional robots; high-throughput robotic technologies. Award Information Award sizes NIH funded research projects expected range approximately 100,000 250,000 per year direct costs, durations one five years.  award exceed 250,000 per year direct costs. Estimated program budget, number awards average award size duration subject the availability funds.  Determination awards based three criteria: 1) availability funds, 2) program priorities, 3) scientific merit. Subsequent grant administration procedures be accordance the policies the awarding Institute. Application Preparation Submission Instructions Applications submitted response this program announcement/solicitation should prepared submitted accordance the general guidelines contained the NSF Grant Proposal Guide GPG).  Applications must submitted the NSF, to NIH.  complete text the GPG available electronically the NSF Web Site at: http://nsf.gov/publications/pub_summ.jsp?ods_key=gpg.   Applicants reminded identify NSF program announcement number the program announcement block the NSF Cover Sheet Proposal the National Science Foundation.  Compliance this announcement critical determining relevant application processing guidelines.  Failure submit information delay processing. Budgetary Information Cost sharing not required applications submitted this funding opportunity. Budgets should include travel funds the PD/PI team members attend annual NRI Principal Investigators' meeting. NIH Process goal this activity to involve multiple agencies using application one review. meet NIH requirements, those applications are identified potential funding participating NIH Institutes Centers ICs), applicant organization be required submit R01application an NIH-approved format directly the Center Scientific Review http://www.csr.nih.gov/) the NIH.  PD/PIs invited submit NIH receive further information submission procedures the NIH. NIH application not allowed increase proposed budget change scientific content the application the converted submission the NIH. The summary statement be presented the involved IC's National Advisory Council the second level review. Subsequent the Council review, NIH ICs make funding determinations selected awards be made. Grant administration procedures NIH awardees, including those related New Early Stage Investigators http://grants.nih.gov/grants/new_investigators/) be accordance the policies NIH. Please note applications be submitted review the NSF December 11, 2012. Notification applications selected potential funding the participating NIH ICs be received the end March, 2013.  converted submission NIH be due April 9, 2013, will an extremely short conversion time.  applicant organization want work closely their Sponsored Programs Office assure timely submission during narrow submission window. earliest project start date be July 1, 2013. Inquiries Written telephone inquiries encouraged.  NIH Program contacts listed below. Please the NSF program announcement names contact information each the participating NSF Directorates http://www.nsf.gov/nri.   Louis Quatrano, Ph. D. Program Director, BSRE, NCMRR Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institutes Health 6100 Executive Blvd, Rm 2A03, MSC 7510, Bethesda, MD 20892-7510 Rockville, MD 20852 express/courier service) Office:  301-402-4221 Fax:  301-402-0832 Email: quatranl@mail.nih.gov    Grace C.Y. Peng, Ph.D., National Institute Biomedical Imaging Bioengineering NIBIB) 6707 Democracy Blvd., Bethesda, MD 20892 Telephone: 301-451-4778;  Fax: 301-480-1614 Email: penggr@mail.nih.gov   http://www.nibib.nih.gov Lyndon Joseph, Ph.D Health Scientist Administrator Division Geriatrics Clinical Gerontology National Institute Aging, NIH, DHHS NIA) 7201 Wisconsin Avenue, Suite 3C307 Bethesda, MD 20892-9205 Telephone: 301-496-6926 Fax: 301-402-1784 Email: Josephlj@nia.nih.gov         www.nia.nih.gov   Daofen Chen, Ph.D. Program Director Systems Cognitive Neuroscience National Institute Neurological Disorders Stroke NINDS) NIH Neuroscience Center, Room 2176 6001 Executive Boulevard Bethesda, MD 20892-9523 FEDEX 20852) Phone: 301) 496-9964, FAX: 301) 402-1501 Email: daofen.chen@nih.gov   Paul A. Cotton, PhD, RD, Program Director National Institute Nursing Research NINR) 6701 Democracy Blvd, Ste. 710 Democracy Plaza Bethesda, MD 20892-4870 Courier zip: 20817) Phone: 301.402.6423 Fax: 301.451.5647 Email: Paul.Cotton@nih.gov     http://www.ninr.nih.gov/    Rosemarie Filart MD, MPH, MBA National Institutes Health National Center Advancing Translational Sciences NCATS) Democracy Plaza 6701 Democracy Boulevard, MSC 4874 Bethesda, Maryland 20892-4874 Telephone: 301-642-5421 Fax: 301-480-3661 Email: filartr@mail.nih.gov