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Extension Expiration Date PA-07-085 R01) PA-06-392 R21) - Research Autism Autism Spectrum Disorders Notice Number: NOT-MH-09-003 Key Dates Release Date: January 16, 2009 Expiration Date: September 8, 2009 Issued National Institute Mental Health NIMH), http://www.nimh.nih.gov) National Institute Deafness Other Communication Disorders NIDCD), http://www.nidcd.nih.gov) National Institute Child Health Human Development NICHD), http://www.nichd.nih.gov) National Institute Neurological Disorders Stroke NINDS), http://www.ninds.nih.gov) National Institute Environmental Health Sciences NIEHS), http://www.niehs.nih.gov) National Institute Nursing Research NINR), http://www.ninr.nih.gov) Office Dietary Supplements ODS), http://ods.od.nih.gov) purpose this notice to extend expiration dates PA-07-085 R01) PA-06-392 R21) - Research Autism Autism Spectrum Disorders until September 8, 2009. extension being at time allow approval adoption the Strategic Plan Autism Spectrum Disorders ASD) Research, was mandated the Combating Autism Act 2006 P.L. 109-416).  Through Act, Congress intended rapidly increase, accelerate pace, improve coordination scientific discovery ASD research.  Once new Strategic Plan adopted, goals it be incorporated updated FOAs ASD research.  FOAs be updated reissued ensure they reflect most current priorities ASD research.  Extending Funding Opportunity Announcements FOAs) until September 8, 2009 also coincide the expiration dates the R03 PA-06-391) FOA the same title.  After September 8, 2009, applicants must apply response the updated FOAs, issued. Inquiries Inquiries regarding Research Autism Autism Spectrum Disorders FOAs be directed to: Lisa Gilotty, Ph.D. Division Developmental Translational Research National Institute Mental Health 6001 Executive Boulevard, Room 6179, MSC 9617 Bethesda, MD 20892-9617 Telephone: 301) 443-3825 Fax: 301) 480-4415 Email: gilottyl@mail.nih.gov

Addendum NOT-NS-09-005, NINDS Administrative Supplements Collaborative Activities Promote Translational Research CAPTR)” Notice Number: NOT-NS-09-006 Key Dates Release Date:  January 13, 2009 Issued National Institute Neurological Disorders Stroke NINDS), http://www.ninds.nih.gov/) purpose this Notice to add R00 Pathway Independence mechanism the list grants eligible CAPTR administrative supplements previously restricted R01s, R37s, P01s).  original K99/R00 grantee to transitioned the Research Phase R00) the award prior the submission date March 23, 2009) the CAPTR administrative supplement request.  other career development K) awardees eligible apply a CAPTR supplement.   other aspects NOT-NS-09-005 remain unchanged.  full text the Notice, was published December 29, 2008, be accessed http://grants.nih.gov/grants/guide/notice-files/NOT-NS-09-005.html. Inquiries Inquiries regarding Notice be directed the NINDS Program staff listed NOT-NS-09-005. 

Guidance Submitting Applications the Roadmap Molecular Libraries Assay Development High-Throughput Screening Program: PAR-08-024 Notice Number: NOT-RM-09-008 Key Dates Release Date: January 2, 2009 Issued The National Institute Neurological Disorders Stroke NINDS), http://www.ninds.nih.gov/), behalf the Roadmap Molecular Libraries Initiative. purpose this notice to provide additional guidance investigators preparing applications the Assay Development High-Throughput Screening Program PAR-08-024 http://grants.nih.gov/grants/guide/pa-files/PAR-08-024.html). Background: Roadmap Assay Development High Throughput Screening HTS) Program serves a key incubator funding development assay projects HTS will eligible advance the Molecular Libraries Probe Production Centers Network MLPCN; https://mli.nih.gov/mli/mlpcn/mlpcn-probe-production-centers/) completed. HTS-ready assays then screened a Network Center against Molecular Libraries Small Molecule Repository MLSMR; http://mli.nih.gov/mlsmr/index.php), promising small molecule hits further developed molecular probes. present, projects funded the Assay Development HTS Program eligible rapid entry the MLPCN Year 2 the R21 award. year 2 Investigators asked submit Fast Track request screening the Program Director is based their progress report the end Year 1 the award. Roadmap Molecular Libraries Project Team provides technical review these requests a monthly basis, placing emphasis project readiness the need probes the proposed target. Upon approval this Project Team projects immediately assigned a Network Screening Center implementation, the investigator awarded 25,000 direct costs) be used facilitating effective collaboration between assay provider the assigned Center the HTS probe development project. CLARIFICATION: the present notice, NIH advising applicants the PAR-08-024 Program they not need request Year 2 funding the R21 application order enter MLPCN their assay project after preparation completed funded Year 1 the award). R21 applications be limited a Year 1 request funding assay development to 100,000 direct costs), will still able enter MLPCN the assays HTS-ready using Fast Track request process described the preceding section. Upon approval this request the Project Team, investigators funded the R21 receive 25,000 direct costs) via Roadmap Supplement, be used previously described) establishing effective Investigator:Center collaboration. Inquiries Further information regarding eligibility the PAR-08-024 Program, information preparing Fast Track requests MLPCN entry, be obtained contacting Mark Scheideler, Ph.D., Program Director the Roadmap Assay Development HTS Fast Track Programs, the following email address: scheidelerm@ninds.nih.gov