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-Purpose. The goal of this funding opportunity announcement (FOA) is to implement a program of cooperative agreements that will support milestone-driven resource-related projects focused on providing products and services that are required for the pre-clinical testing of new therapeutics, and that are specific to neurology. -Mechanism of Support. This FOA will utilize the U24 Resource-Related Research Projects Cooperative Agreements grant mechanism. -Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received.

-Purpose. This Funding Opportunity Announcement (FOA), from the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), requests applications for projects intended to complete preliminary steps in the pipeline for the preclinical development of therapeutics for neuromuscular diseases. Such projects, if successful, should lead directly to a subsequent project that will include all remaining activities for submission of an Investigational New Drug (IND) or Investigational Device Exemptions (IDE) application to the Food and Drug Administration (FDA). Only Aims required for therapy development can be supported in this program.This program excludes clinical research, basic research, and studies of disease mechanisms. -Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism. -Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the quality, duration, and costs of the applications received.The participating organizations intend to commit a total of $1 million per year to fund meritorious applications that address the goals of this FOA.

-Purpose. The goal of this funding opportunity announcement (FOA), from the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), is to support preclinical development and testing of new therapies for neuromuscular diseases. The program will facilitate solicitation, development, and review of therapy-directed projects to accelerate the translation of basic research discoveries into therapeutic candidates for clinical testing. This program is specifically directed at projects that include therapeutic leads with demonstrated activity against the intended disease target. The program supports preclinical optimization and testing of these leads and projects must be sufficiently advanced that an IND or IDE application to the FDA can be submitted by the end of the project period. The program does not support early-stage therapeutic discovery activities such as high throughput screening. The program also excludes clinical research, basic research, and studies of disease mechanism. This is a milestone-driven cooperative agreement program involving participation of NIH staff in the development of the project plan and monitoring of research progress.

-Purpose: The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) to eligible institutions as the primary means of supporting predoctoral and postdoctoral research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nations biomedical, behavioral and clinical research agenda.The primary objective of the T32 program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program supports predoctoral, postdoctoral and short term research training programs at domestic institutions of higher education with the T32 funding mechanism. Note that programs solely for short-term research training should not apply to this announcement, but rather the separate (T35) NRSA Short-Term Institutional program exclusively reserved for short-term programs(see PA-08-227). -Mechanism of Support:This Funding Opportunity Announcement (FOA) will utilize the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32). -Funds Available and Anticipated Number of Awards: Because the nature and scope of the proposed research training will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the number, quality, duration, and costs of the applications received

-Purpose. This Funding Opportunity Announcement (FOA), the Fogarty International Research Collaboration Basic Biomedical (FIRCA-BB) Research Award program, facilitates collaborative basic biomedical research between scientists supported by the National Institutes of Health (NIH) and investigators in low- to middle-income countries (LMIC). All non-AIDS-related biomedical research topics that are supported by the NIH, including basic, clinical, and applied research that does not involve behavioral or social science topics and techniques, are eligible for inclusion under the FIRCA-BB program.For behavioral and social science (BSS) research, see the companion Funding Opportunity Announcement (FOA), the Fogarty International Research Collaboration Behavioral and Social Sciences (FIRCA-BSS) Research Award program, (PAR-08-223).Special consideration will be given to proposed research that addresses significant global health problems, particularly those of high relevance to an LMIC country or region. This FOA includes an additional review criterion of Research Capacity Building (see Section V.2.Application Review and Selection Process). -Mechanism of Support. This FOA will utilize the NIH Small Research grant (R03) mechanism, with additional eligibility, project period and funding restrictions.The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources.

-Purpose. The goal of this Funding Opportunity Announcement (FOA) is to encourage research that will improve the quality and scientific power of data collected in the behavioral and social sciences, relevant to the missions of the participating NIH Institutes and Centers. -The participating NIH Institutes and Centers invite qualified researchers to submit research grant applications aimed at improving and developing methodology and measurement in the behavioral and social sciences through innovations in research design, data collection techniques, measurement, and data analysis techniques. -Research that addresses methodology and measurement issues in diverse populations, issues in studying sensitive behaviors, issues of ethics in research, issues related to confidential data and the protection of research subjects, and issues in developing interdisciplinary, multimethod, and multilevel approaches to behavioral and social science research is particularly encouraged, as are approaches that integrate behavioral and social science research with biological, physical, or computational science research or engineering.

-Purpose. The goal of this Funding Opportunity Announcement (FOA) is to encourage research that will improve the quality and scientific power of data collected in the behavioral and social sciences, relevant to the missions of the participating NIH Institutes and Centers. -The participating NIH Institutes and Centers invite qualified researchers to submit research grant applications aimed at improving and developing methodology and measurement in the behavioral and social sciences through innovations in research design, data collection techniques, measurement, and data analysis techniques. -Research that addresses methodology and measurement issues in diverse populations, issues in studying sensitive behaviors, issues of ethics in research, issues related to confidential data and the protection of research subjects, and issues in developing interdisciplinary, multimethod, and multilevel approaches to behavioral and social science research is particularly encouraged, as are approaches that integrate behavioral and social science research with biological, physical, or computational science research or engineering.

-Purpose. The goal of this Funding Opportunity Announcement (FOA) is to encourage research that will improve the quality and scientific power of data collected in the behavioral and social sciences, relevant to the missions of the participating NIH Institutes and Centers. -The participating NIH Institutes and Centers invite qualified researchers to submit research grant applications aimed at improving and developing methodology and measurement in the behavioral and social sciences through innovations in research design, data collection techniques, measurement, and data analysis techniques. -Research that addresses methodology and measurement issues in diverse populations, issues in studying sensitive behaviors, issues of ethics in research, issues related to confidential data and the protection of research subjects, and issues in developing interdisciplinary, multimethod, and multilevel approaches to behavioral and social science research is particularly encouraged, as are approaches that integrate behavioral and social science research with biological, physical, or computational science research or engineering.

Purpose. The National Institute of Allergy and Infectious Diseases (NIAID), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Neurological Disorders and Stroke (NINDS) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, will co-sponsor this FOA to support applications from institutions/organizations that propose innovative investigations in primary immunodeficiency diseases with a focus on ex vivo studies with human specimens and on studies with existing or new animal models. This FOA will also support novel clinical strategies, not including clinical trials, to detect primary immunodeficiency diseases, to identify the molecular basis of these diseases, and to develop innovative therapies for primary immunodeficiency diseases. Investigators who have no prior history of receiving independent NIH funding in this field are encouraged to apply.

-Purpose. This funding opportunity announcement (FOA) solicits Conference Grant (R13/U13) applications from applicant organizations for meetings and networks that will facilitate interdisciplinary research partnership among investigators.The goal is to create opportunities for forming strong and effective multi-disciplinary scientific teams to address basic, translational, or clinical research problems in rehabilitation or management of chronic disease, including mental disorders. -Mechanism of Support. This Funding Opportunity Announcement (FOA) will utilize the R13 grant mechanism -Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.