SUP Research Supplements to Promote Re-Entry and Re-Integration into Health-Related Research Careers

Administrative supplements to currently active NIH research grants to support individuals with high potential to re-enter or reinegrate into an active research career after an interruption.

Program Announcement

Appointee Eligibility
Postdoctorate/residency; early career investigators; U.S. citizens or permanent residents

Institution Eligibility
U.S. domestic institutions

Additional Information

The Re-entry Supplements program is intended to provide mentored research training opportunities for a minimum of 1 year to re-enter biomedical research to individuals with doctoral degrees, who have interrupted their research careers for family responsibilities or other qualifying circumstances. In general, the duration of the career interruption should be at least six months for re-entry purposes, and no more than eight years.

The Re-integration Program addresses the critical need to provide individuals, including predoctoral students, who are adversely affected by unsafe or discriminatory environments resulting from unlawful harassment, to rapidly transition into new safer, and more supportive research environments. The goal is to provide these individuals a timely and seamless continuation of their research training programs and to safely reintegrate into the biomedical workforce. Unsafe environments may consist of threatening behavior such as sexual and gender harassment; harassment based on being a member of a racial, ethnic, sexual, or gender minority group; disability-based aggression; aggressions associated with religion; and other similar circumstances.  

In all cases, the proposed research experience must be within the scope of the NIH-supported grant project and be an integral part of the approved, ongoing research of the parent award. The candidate’s proposed mentored research experience must have the potential to contribute significantly to the research career development of the candidate. The individual supported under this supplemental award must be allowed to act as a full participant in the research project and must be given an opportunity to update and enhance their research capabilities. This will allow the candidate to begin the process of re-establishing a career as a productive, competitive investigator. It is anticipated that by the completion of the supplement support period, the re-entry/re-integration scientist will be prepared to apply for a fellowship (F), career development (K) award, a research award (R), or other types of independent research support. Supplemental awards are expected to strengthen the existing research program and reflect the overall programmatic balance and priorities of the NIH funding program. 

The supplementary information on this page applies to applications requesting selected research supplements to active National Institute of Neurological Disorders and Stroke (NINDS) grants. Its purpose is to clarify the application process for NINDS grantees and is not intended to replace the detailed information in the Notice.

Prior to submission of an application, the Principal Investigator (applicant) should contact Marguerite Matthews, PhD, Scientific Program Manager in the Office of Programs to Enhance Neuroscience Workforce Diversity (, to discuss the proposed supplement. Critical issues to be discussed with the program officer may include, but are not limited to, the research development and mentoring plan activities.

Eligibility for the PA

Candidates with a doctoral degree-seeking re-entry: In general, the duration of the career interruption should be for at least six months and no more than eight years. Examples of qualifying interruptions would include child-rearing; an incapacitating illness or injury of the candidate, spouse, partner, or a member of the immediate family; and military service. The program is not intended to support additional graduate training and is not intended to support career changes from non-research to research careers for individuals without prior postdoctoral research training. It is anticipated that at the completion of the supplement, the re-entry scientist will be in a position to apply for a career development (K) award, a research award, or some other form of independent research support. The candidate should not be engaged in full-time paid research activities at the time of re-entry (temporary part-time is acceptable).

Re-integration: Candidates with doctoral degrees and graduate students seeking to transition out of unsafe research environments because of discriminatory and unlawful harassment are eligible to apply for re-integration supplements as soon as supplement support to continue research training in a new and safe research environment has been identified.

Candidates who have begun the re-entry/reintegration process through a fellowship, traineeship, or similar mechanism are not eligible for this program. Awards will be limited to citizens or noncitizen nationals of the United States or to individuals who have been lawfully admitted for permanent residence (i.e., who possess an Alien Registration Receipt Card) at the time of application.

Supplement Format
The program is designed to bring the scientist’s existing research skills and knowledge up-to-date, so that, during or at the completion of the supplement, the scientist will be in a position to apply for a fellowship, career development, or research award. The supplement must be applied to an existing NIH research grant with a minimum of 1 year of funding remaining.

Application instructions are available in NOT-OD-21-134 under "Application and Submission Information."

Competitive applications will have the following:

  • Defined research objectives that serve as a basis for the supplementee’s autonomy as a research investigator and transition from the supplementee phase to independence. The application should include plans for a project that both fits the scope of the parent grant and ultimately evolves into a future project clear of competition and demonstrates ownership/ non-dependence on mentor. A brief description of the Parent Grant specific aims must be provided.
  • A carefully planned mentoring program developed by the mentor and the supplementee. The research and training timeline should include both scientific and administrative milestones that will be needed to secure independence.
  •  The personal statement of the candidate's biosketch should address: research objectives and career goals, research experience prior to onset of hiatus, length of and reason for career hiatus, a description of how the candidate has kept current or attempted to keep current their field, and identification of any steps already taken toward re-entry (if any, such as attending scientific meetings).
  • Evidence of a publication record in respected peer-review journals within the field.
  • Reference letter(s) from either past mentors or advisors that address the trajectory of the candidate prior to the hiatus. The supporting letters should provide positive evidence of the productivity level and likelihood of the candidate transitioning to independence prior to the hiatus.
  • Strength of the mentor’s commitment to the applicant's continued research career development and independence.
  • Strength of institutional commitment to immediately address unlawful harassment and fully support and protect the candidate’s pursuit of continued research training in a safe and supportive environment.

A maximum of 3 years of support can be awarded. During the first budget period, funds will be provided as an administrative supplement to the parent grant. In subsequent years, continued funding for the supplement is contingent on funding of the parent grant and the re-entry/re-integration candidate's progress, and cannot extend beyond the current competitive segment of the parent grant.

Allowable Costs and Other Provisions


Graduate (Predoctoral) And Health Professional Students*
(*Eligible for re-integration supplements only)

Individuals in Postdoctoral Training

Investigators Developing Independent Research Careers 

Salary & Fringe Benefits

Consistent with applicant institutional salary policies, total compensation (salary, fringe benefits, and tuition remission) cannot exceed zero level NSRA postdoc stipend

Must be in accordance with the salary structure of the grantee institution, consistent with the level of effort, and may not exceed the maximum allowable NRSA stipend level for postdoctoral fellows in effect at the time of appointment.

Up to $75,000 salary plus fringe benefits per year up to $85,000 total direct costs

Supplies & Travel

$4,000 per year

$6,000 per year

$10,000 per year









Period of Support

Coincident with research doctoral and health professional degree program, typically up to three years

Typically two years

Typically two years


Submission and Receipt of Applications
Prior to submission of an application, the Principal Investigator (applicant) should contact Marguerite Matthews, PhD, Scientific Program Manager in the Office of Programs to Enhance Neuroscience Workforce Diversity (

In making requests, the grantee institution, on behalf of the PI of the parent grant and in cooperation with the applicant individual, must submit the request for supplemental funds. 

There are several options available to electronically submit Re-Entry supplement applications. These include NIH ASSIST, institutional system-to-system (S2S), and Workspace. NIH also offers a streamlined system through the eRA Commons for submitting administrative supplements. Login to the eRA Commons, identify the parent award, and prepare an administrative supplement request. All candidates for supplemental re-entry award support must also have a profile in the eRA Commons.

Include the candidate’s eRA Commons Username and attach the Research Experience Plan (described below in the PHS 398 Research Plan Form), Candidate Biosketch (described in the Senior/Key Personnel Form, also called the Applicant Biosketch), and the Candidate Eligibility Statement (described in Other Project Information/Appendix, also called the Applicant Eligibility Statement) in the fields provided. 

Budget information should be entered for the grantee institution in the fields provided. There is no template or form available for subaward information; instead, all subaward information should be included as a separate attachment showing the funds requested (by budget period) using the same categories provided for the grantee institution. Also include a budget justification for the subawardee institution in the same file.

For more guidance, please see the eRA Commons user guide.

Review and Award of Applications

We accept applications on a rolling basis. Allow for 1-2 months after the time of submission for a final funding decision.

Administrative review criteria are available in NOT-OD-21-134 under "Application Review Information."

Funding decisions are generally dependent on:

  1. The merit of the application and the proposed project activities (i.e., the career development/mentorship plan)
  2. The potential for continued research progress of the candidate
  3. The availability of funds.



Michelle Jones-London, Ph.D. | Chief, Office of Programs to Enhance Neuroscience Workforce Diversity

Marguerite Matthews, Ph.D. | Program Director



Anti-Sexual Harassment Resources

NIH Director's Statement on Harassment

NIH Process for Handling Allegations of Sexual Harassment on an NIH-Funded Project at a Recipient Institution

Re-Entry Supplement Information from NIH

Awardee Success Stories

Loan Repayment Program

How to Apply