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The purpose of this notice is to inform applicants of the National Institute of Neurological Disorders and Stroke's (NINDS) participation in RFA-ES-23-007 “Exploratory Grants for Climate Change and Health Research Center Development (P20 Clinical Trial Optional)”. This notice is effective for the May 1, 2023 due date and subsequent due date(s). Changes to the Notice of Funding Opportunity (NOFO) are shown below.