Research Program Award (R35)
Massachusetts Institute of Technology, Cambridge, MA
Dr. Myriam Heiman’s research is focused on understanding enhanced vulnerability of certain neuronal types to death or dysfunction. Her team uses innovative approaches to study the cell biology of neuronal cell types relevant in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and Huntington’s diseases. The goals of this research program are to perform cell type-specific transcriptional studies of Huntington’s disease-relevant cell types to identify and test driver genes and pathways. A better understanding of these key driver genes underlying diseases like Huntington’s disease could ultimately lead to better therapeutics targets.