Manisha Patel, Ph.D.

Javits Award
photo of Manisha Patel
University of Colorado, Aurora, CO

Dr. Manisha Patel's research focuses on understanding the role of reactive oxygen species (ROS) and metabolic mechanisms in neuronal disorders such as epilepsy and toxicant-induced brain injury. Dr. Patel's project builds upon twenty years of research to identify the redox and metabolic mechanisms of seizure-induced brain injury. The project aims to test a novel hypothesis linking neuronal mitochondrial ROS, resulting in mitochondrial dysfunction associated with astrogliosis initiation. This work could help to develop novel metabolism-based therapies for epilepsy.