Aaron DiAntonio, M.D.,Ph.D.

Javits Award
Photo of Aaron DiAntonio, M.D., Ph.D. - Javits Awardee FY20
Washington University , St. Louis, MO

Dr. Aaron DiAntonio combines genetics, cell biology, biochemistry, and physiology in both Drosophila and mice to investigate molecular mechanisms that control the formation, maintenance, and repair of neural circuits in development and disease. For this project, he is examining the dual leucine zipper kinase (DLK) as a key sensor of axon injury that regulates the three primary neuronal responses to axon injury-axon degeneration, axon regeneration, and neuronal cell death. Investigating the function and regulation of the DLK pathway informs its potential as a therapeutic candidate for a wide range of neurological diseases.