Bruce D. Trapp, Ph.D.

Research Program Award (R35)
Photo of Bruce Trapp, Ph.D. FY17 Research Program Award (R35) recipient
Institution
Cleveland Clinic Lerner Research Institute, Cleveland, OH
Awarded Project
Pathogenesis of neurological disability in primary diseases of myelin

Myelin is a material surrounding nerve fibers that facilitates rapid signal conduction and provides essential support for neuronal growth and survival. Diseases associated with myelin damage or loss, such as multiple sclerosis, lead to nerve fiber degeneration. To inform strategies that may prevent or repair damage in myelin diseases, Dr. Trapp studies how myelin supports neuronal survival, how demyelination affects neurons and synapses, and how demyelination occurs.