Linda McGavern, Ph.D.

Job Title
Program Director
Linda McGavern
Division of Neuroscience
Cluster, Section, or Program
Neurodegeneration, Dementia, and Repeat Expansion Disorders
Areas of Interest

Portfolio: Alzheimer's disease (AD), Limbic-predominant Age-related TDP-43 Encephalopathy (LATE), and Multiple Etiology Dementia (MED)    

Additional Keywords: APP, presenilins, beta-amyloid, ApoE; tauopathies; Alzheimer’s Disease-Related Dementias (ADRD) co-pathologies (e.g., tau, alpha-synuclein, TDP-43, TMEM106B, vascular)

Contact Email

Dr. Linda McGavern joined the National Institute of Neurological Disorders and Stroke (NINDS) in 2009 and currently is a Program Director in the Neurodegeneration, Dementia, and Repeat Expansion Disorders cluster where she is responsible for the NINDS Alzheimer’s Disease (AD), Limbic-predominant Age-related TDP-43 Encephalopathy (LATE), and Multiple Etiology Dementia (MED) portfolios, with a main focus on basic disease-related molecular mechanisms and shared pathways across neurodegenerative disorders. Previously, Dr. McGavern was a Scientific Project Manager in the NINDS Division of Translational Research where she administered the NINDS Cooperative Agreement Program in Translational Research and the Cooperative Research to Enable and Advance Translational Enterprises for Biotechnology Products and Biologics (CREATE Bio) Program to allow therapeutic development projects to successfully progress towards Investigational New Drug (IND) applications. Prior to joining NINDS, Dr. McGavern was a Project Manager at Favrille, Inc in San Diego, CA where she coordinated projects to support a Biologic License Application (BLA). Dr. McGavern received her Ph.D. in Molecular Neuroscience from Mayo Graduate School, MN, and completed a postdoctoral fellowship at The Scripps Research Institute, CA where she studied NADPH oxidase enzyme complexes and the necessary protein subunit associations required for their function and regulation.