Dr. Perez's research program has focused on understanding transmission in descending motor pathways and spinal cord networks during motor behaviors in humans with and without spinal cord injury (SCI), with the long-term goal of maximizing the activity of spared pathway connections to enhance recovery potential. For this project, she will integrate information across residual networks in the subacute and chronic phases of SCI and focus on understanding transmission, hyperreflexia, and neuroplasticity-based therapies. The success of this research may increase our understanding of the neural control of movement and symptoms (including spasticity and muscle spasms) in other neurological disorders. It may also provide new avenues for treatments and assessment of humans with SCI and other neurological disorders.