K99/R00 - NIH Pathway to Independence Award

K99/ R00

K99/R00 - NIH Pathway to Independence Award

Purpose
To support both an initial mentored research experience (K99) followed by independent research (R00) for highly qualified, postdoctoral researchers, to secure an independent research position. Award recipients are expected to compete successfully for independent R01 support during the R00 phase.

Program Announcements
NINDS K99/R00 - No Independent Clinical Trials - PA-19-130

NINDS K99/R00 - Clinical Trial Required - PA-19-129

NINDS K99/R00 - Basic Experimental Studies with Humans Required - PA-19-090

Due Dates for New/Resubmission Applications
February 12/March 12,  June 12/July 12,  October 12/November 12

PD/PI Eligibility
U.S. citizens, permanent residents, or non-U.S. citizens; research or clinical doctorate holders

Institution Eligibility
U.S. domestic institutions

Additional Information
At the application due date, applicants for a NINDS K99/R00 can have no more than 48 months (49 months for resubmission applications) of research experience following the completion of the requirements for their doctorate. Applicants must be in a mentored postdoctoral, non-faculty position to be considered for a K99/R00 award from NINDS. Applicants with a job title other than that typical of a postdoctoral researcher are strongly encouraged to contact the NINDS Office of Training & Workforce Development prior to applying.

See more information about eligibility for an NINDS K99/R00

All applications submitted to NINDS are reviewed in-house by the NST 2 study section.

NINDS will only consider applications for research that falls within its mission. Applicants are strongly encouraged to contact the NINDS Office of Training & Workforce Development prior to applying to confirm mission relevance of their proposed project.

Salary and Research Costs 
For mentored (K99 phase) candidates at an extramural institution, NINDS will provide up to $50,000 per year for salary support, plus fringe, and up to $20,000 for research support costs. For applicants with medical degrees who are licensed to practice, NINDS will provide up to $100,000 per year for salary support. Applicants must commit a minimum of 9 person months effort to the K99/R00 research during both phases of the award (Note: Neurosurgeons must commit a minimum of 6 person months effort to the K99/R00 research during both phases of the award). 

For independent (R00 phase) candidates at an extramural institution, NINDS will provide up to $249,000 of support per year. This amount includes salary support, fringe, and research costs. Applicants must obtain an offer for a tenure-track or equivalent position by the end of the K99 phase to be eligible for R00 support.

See more information about NINDS requirements for transition to the independent (R00) phase (pdf, 103kb).

List of Funded Awards
NINDS K99/R00 Pathway to Independence Award Recipients

Not sure whether your research qualifies as a clinical trial or basic experimental study with humans? 
Applicants are strongly advised to consult with NINDS program staff prior to submitting an application with human subjects to determine the appropriate funding opportunity. See the NIH definition of a clinical trial and NIH guidance for basic experimental studies with humans for more information.