Very little is known about how sensorimotor networks in the spinal cord are organized at a cellular level. Dr. Goulding’s research aims to use cutting-edge genetic manipulations and sensitive behavioral assays to deconstruct the cellular composition and synaptic connectivity of these sensorimotor circuits. The intent is to functionally define the neuronal cell types that make up the sensorimotor circuitry, and to generate a connectivity map that can be used to construct a model of the organization of sensorimotor circuitry. This knowledge can elucidate the control systems that regulate movement and lead to the development of new approaches for treating spinal motor disorders and spinal cord injury, as well as neuropathic pain and chronic itch.