NINDS accepts applications for Exploratory/Developmental Bioengineering Research Grants (EBRG), Bioengineering Research Grants (BRG), and Bioengineering Research Partnerships (BRP) that address technology development specific to the NINDS mission of basic and translational research to reduce the burden of neurological diseases.
NINDS will entertain bioengineering applications if they focus on technology development relevant to normal or disordered neural function and to the prevention, repair or replacement of compromised neural function. The EBRG, BRG and BRP represent a continuum of project scale, feasibility and applicability from small, exploratory proposals to large, translational partnerships. The EBRG mechanism should be used to explore pilot projects to address feasibility for a subsequent BRP application. The BRG mechanism is preferred for combining focused research groups to test investigative hypotheses about basic technology development and early-/mid-stage refinement of technology performance. Innovative combinations of disciplines, techniques, and newly collaborating research groups are encouraged. BRP applications should bring together more expansive partnerships among investigative, biomedical and bioengineering disciplines to achieve well-defined goals or deliverables. For example, partnerships might span academic entities (biological, bioengineering, biomedical groups), device industries, commercial distribution companies, medical instrument concerns, small business companies, etc. to accomplish translation of well-developed technology to applied feasibility or commercialization. Final stages of translation for FDA investigational device exemption (IDE) and early-stage clinical trials might be a candidate for one of the NINDS cooperative agreement programs.
Applicants are strongly encouraged to discuss their research and application plans with an appropriate Program Director prior to submission. Applications with budgets exceeding $500,000 in any fiscal year must be pre-approved for acceptance by NINDS. Inquiries should be made at least six (6) weeks prior to application deadlines.