Frank Shewmaker, Ph.D.

Job Title
Program Director
Frank Shewmaker
Division of Neuroscience
Cluster, Section, or Program
Neurodegeneration, Dementia, and Repeat Expansion Disorders
Areas of Interest

Portfolio: Frontotemporal Dementia (FTD), Frontotemporal Lobar Degeneration (FTLD), Progressive Supranuclear Palsy (PSP), Corticobasal Degeneration (CBD), Primary Progressive Aphasia (PPA)    

Additional Keywords: MAPT, tau, FUS, TAF15, TDP-43, C9orf72; proteinopathies; tauopathies;, progranulin, PGRN, granulin,GRN, and TMEM106B; amyloid structural biology; biomolecular condensates and liquid-liquid phase separation (LLPS)

Contact Email

Dr. Frank Shewmaker joined the National Institute of Neurological Disorders and Stroke (NINDS) in 2023 and serves as the Frontotemporal Dementia Program Director. Prior to joining NINDS, he was a Program Director of Protein Biophysics at the National Institute of General Medical Sciences (NIGMS). Dr. Shewmaker earned a Ph.D. in biochemistry from Tulane University and performed his postdoctoral research at the NIH, where he studied the structural properties that enable proteins to form self-propagating amyloid conformations. Before becoming a Program Director at NIGMS, Dr. Shewmaker was an Associate Professor of Biochemistry in the medical school of Uniformed Services University at Walter Reed National Military Medical Center in Bethesda, MD. His research focused on protein aggregation and its consequences to cellular functions.