Beth Anne Sieber, Ph.D.

Dr. Beth-Anne Sieber is a program officer in the Neurodegeneration cluster, managing a research grant portfolio on Parkinson’s disease (PD) and related disorders, dystonia and essential tremor. Her PD grant portfolio includes neurobiological and pharmacological approaches to understand neuronal loss and alterations in circuitry; neuroinflammation and neuroimmune aspects of PD and the role of the gut-brain axis. Dr. Sieber also manages the Udall Centers of Excellence for PD Research program and chairs the NINDS PD Work Group (PDWG), which coordinates  PD research programs and related activities across extramural NINDS. Prior to joining the NINDS, Dr. Sieber served as a program director at the National Institute of Mental Health (NIMH), where she managed a grant portfolio in developmental neurobiology and co-chaired related efforts for the NIH Neuroscience Blueprint. She received a bachelor’s degree in biology and psychology from Rutgers University and a Ph.D. in Physiology and Neurobiology from a joint program between Rutgers and the University of Medicine and Dentistry of New Jersey. Her graduate studies focused on preclinical models of dopamine neuron development and degeneration, with emphasis on utilizing neuropharmacological and neurochemical approaches to determine the roles of neuronal-glial interactions and neurotrophic factors in these processes. Postdoctoral studies at the Karolinska Institute utilized molecular approaches to elucidate the role of neurotrophic factors and receptor tyrosine kinases in survival and function of dopamine neurons.