Neuroimmunology and Virology
Appointed in December 2024, Dr. Yair Mina is a Staff Clinician in the Experimental Immunotherapeutics Unit of the Neuroimmunology Branch (NIB). Dr. Mina graduated from Tel Aviv University School of Medicine, where he obtained his B.Med.Sc and M.D. degrees with distinction. Dr. Mina completed an Internship (2012-2013) and Neurology Residency (2013-2018) at Tel Aviv Sourasky Medical Center, and then served there as senior staff (2018-2019). Between 2019 and 2022, he completed a clinical research fellowship in Neurovirology and Neuroimmunology at NINDS and was involved in research on Progressive Multifocal Leukoencephalopathy (PML) as well as neurological complications of HIV, SARS-CoV2 and HTLV. In 2022 he returned to Tel Aviv Sourasky Medical Center and served as the head of the Neuroinfectious Diseases Clinic as part of the Encephalitis Center. In December 2024, Dr. Mina rejoined NINDS, this time as a Staff Clinician in the Neuroimmunology Branch, where he oversees all clinical activities for patients with PML receiving experimental immunotherapeutics as part of the branch's active clinical trials.
Research Interests:
Dr. Mina's research focuses on neuroinfectious diseases, with particular focus on progressive multifocal leukoencephalopathy (PML) and the study of virological and immunological mechanisms associated with JCV infection. He is an associate investigator on the research protocols of the Neuroimmunology Branch including the Natural History Study of PML which serves as a platform for characterizing host factors that affect susceptibility to JCV reactivation and development of treatment strategies, as well as various protocols for interventional immunotherapeutics. He is specifically interested in development of imaging and laboratory biomarkers of disease progression, which could be applied to early phase clinical trials.
Selected Publications
Mina Y, Kline A, Manion M, et al. Neurological manifestations of nontuberculous mycobacteria in adults: case series and review of the literature. Frontiers in Neurology. 2024;15.
Mina Y, Enose-Akahata Y, Hammoud DA, et al. Deep Phenotyping of Neurologic Postacute Sequelae of SARS-CoV-2 Infection. Neurol Neuroimmunol Neuroinflamm. 2023;10(4):e200097. Published 2023 May 5.
Mina Y, Azodi S, Dubuche T, et al. Cervical and thoracic cord atrophy in multiple sclerosis phenotypes: Quantification and correlation with clinical disability, NeuroImage: Clinical, 2021;102680.
Mina Y, Wu T, Hsieh H-C, et al. Association of White Matter Hyperintensities with HIV Status and Vascular Risk Factors. Neurology 2021;96:e1823.
Mina Y, Schechner V, Savion M, et al. Clinical benefits of FilmArray meningitis-encephalitis PCR assay in partially-treated bacterial meningitis in Israel. BMC Infect Dis 2019;19:713-713.
Mina Y, Fahoum F, Abramovici S, Anis S, Kipervasser S. Clinical correlates and electroencephalographic features of FIRDA in a tertiary center. Acta Neurologica Scandinavica 2019;140:405-413.
Mina Y, Smith, B.R., Nath A. HIV and the Nervous System. In eLS, John Wiley & Sons, Ltd (Ed.). 2020; doi:10.1002/9780470015902.a0000006.pub2
Segal Y, Rotschild O, Mina Y, et al. Epidemiology of autoimmune encephalitis and comparison to infectious causes-Experience from a tertiary center. Ann Clin Transl Neurol. 2024 Sep;11(9):2337-2349.
Goldstein DS, Mina Y, Walitt B, et al. Persistent Autonomic and Immunologic Abnormalities in Neurologic Post-Acute Sequelae of SARS-CoV2 Infection. Neurology. 2024 Sep 24;103(6):e209742.
Maayan Eshed G, Levinson T, Mina Y, et al. West Nile virus encephalitis: Clinical characteristics and a comparison to other infectious encephalitides. J Neurol Sci. 2024 Dec 15;467:123286.
Okar SV, Kawatra KD, Thommana AA, Vultorius DC, Nair G, Gaitán MI, Norato G, Mina Y, Fletcher A, Reich DS, Cortese I. Portable ultra-low-field MRI for progressive multifocal leukoencephalopathy: Case studies, sensitivity, and potential applications. J Neurol. 2025 Feb 11;272(3):193.