Behavioral neuroscience and in vivo pharmacology as it relates to the development of therapeutics to combat long-term addiction.
Matthew Rice, a scientific project manager in the Pain Therapeutics Development Program (PTDP) within NINDS' Division of Translational Research (DTR), supports the Institute's role in the Helping to End Addiction Long-term Initiative, or NIH HEAL InitiativeSM. In that position, he manages therapeutic development projects in the NIH HEAL Initiative portfolio.
Prior to becoming a member of NINDS, Dr. Rice served as a project manager at the National Center for Advancing Translational Sciences (NCATS) managing early therapeutic development projects in the NIH HEAL Initiative portfolio. During his career, he has developed and conducted of a wide range of neuroscience-related research projects including the use of nanoparticles as hemostatic agents for intracerebral hemorrhage, the acute application of nicotine to treat brain injury-induced motor and cognitive deficits, the utility of targeting the microbiota-gut-brain axis for the treatment of brain injury pathology and symptomatology, the efficacy of human neural stem cells for severe penetrating traumatic brain injury, the evaluation of countermeasures to chemical nerve agents, the contribution of hypothalamic neuroendocrine signaling in aging, the application of neural stem cells in the treatment of metabolic syndrome pathologies, and the role of the dopaminergic system in schizophrenia.