Director's Messages
From June 21-22, 2022, NIH will host the 8th Annual Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative Meeting:
Each of us is born with a unique genome made up of DNA that we inherit, and changes to that DNA sequence occur in individual cells over our lifetimes.
Last week, we celebrated the most mysterious and fascinating organ in the body—the brain! —by participating in Brain Awareness Week, March 14-20.
The value of fundamental neuroscience cannot be overstated enough. Since the discoveries of Santiago Ramón y Cajal well over a century ago, basic neuroscience research has continuously advanced our understanding of the workings of the nervous system.
From the Hippocratic corpus, the author writes, “I consider the responsibility of medicine to be to entirely relieve the suffering of the sick and to blunt the extremities of disease” (The Art 3.4-7)1. Note that despite the acknowledgement that disease may only be blunted, in promoting health it is our duty to relieve suffering wherever possible.
In the United States, rare and ultra-rare diseases are defined as conditions that affect fewer than 200,000 or 6,000 people, respectively. While these numbers may seem small, they add up to a large burden: collectively, nearly 30 million Americans are living with one of the roughly 7,000 known rare or ultra-rare diseases.