Press Releases

NIH-funded study identifies brain cells that form boundaries between discrete events. 

Researchers from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene. Studies in mice demonstrate that the therapy could show promise in treating rare, aggressive forms of ALS caused by mutations in the fused in sarcoma (FUS) gene.

NINDS is mourning the loss of Dr. Ann-Marie Broome, a program director in the Division of Translational Research. During her time at NINDS, Ann-Marie played a key role in creating two large and innovative initiatives: the Blueprint Biologics Program and the URGenT Network.

The NIH Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN​) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

NIH study identifies possible target for certain neurodegenerative disorders

NIH study in mice demonstrates the importance of quickly addressing infection