The primary purpose of this randomized controlled trial is to test the effect of Power Training combined with interval Treadmill Training (PT³) on walking capacity and performance in children with CP with walking limitations. To identify key muscular mechanisms associated with improved walking mobility, the effects of PT³ on muscle performance and architecture will be examined. The premise of the PT³ protocol is that a combined impairment and task-specific approach that is developmentally appropriate and targets muscle power deficits specifically, is necessary to drive changes in both clinic and community-based walking activity. In this randomized multi-site clinical trial, 48 ambulatory participants with CP will receive either PT³ or an equivalent dosage of traditional strength training combined with traditional treadmill training (comparison group) for 24 sessions, 3 times per week for 8 weeks. Outcomes will be collected at baseline and immediately post-treatment. Short and long-term retention effects will be assessed at 2 and 6 months post.
Inclusion Criteria: - Diagnosis of bilateral spastic Cerebral Palsy (CP) - Age 10 to 17 years inclusive - GMFCS levels I, II, or III Exclusion Criteria: - Orthopedic or neurosurgery less than 12 months prior to enrollment - Injection therapies (phenol, botulinum toxin) less than 3 months prior to enrollment - Lacking greater than 25 degrees of knee extension