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… of Kentucky , Lexington, KY Dr. Gentry examines the nature and mechanisms of glycogen metabolism and how mis-regulation of these signaling events can lead to … (LD). Recent work suggests that glycogen aggregates in the brain may cause LD. For this proposal, he will use LD as an …
… 2019 Image Cornell University , Ithaca, NY New mechanisms and technologies for understanding post-transcriptional gene … epitranscriptomics – that is, the study of the role and function of mRNA base modifications. The lab also studies … of epitranscriptomic regulation of mRNA expression in the brain, the role of RNA-directed epigenetic silencing in …
… Dong’s research focuses on the mechanisms underlying itch and pain sensation. His lab integrates molecular biology with animal behavior, in vivo imaging, and electrophysiology to gain new insights with the goal of … approach using mouse behavioral models, imaging, and brain tissue analysis to conduct mechanistic studies on a key …
… , San Francisco, CA Calcium Activated TMEM16 Channels and Their Physiological Roles in the Brain Council Dates: October 2013 - May 2014 Independent … molecular properties of calcium-activated TMEM16 channels and their cellular functions in platelets and in cerebellar …
… an intermediate regulatory paradigm between DNA sequences and gene expression, epigenetic mechanisms can exert substantial influence on normal brain function in ways that are only beginning to be … that multiple neurodevelopmental, neurodegenerative, and psychiatric disorders are caused, at least in part, by …
… the molecular mechanisms of prions that cause fatal brain diseases in humans and other species. Dr. Supattapone's group is a pioneer in … that could be leveraged to identify other co-factors and pathways that regulate the normal and infectious prions …
… focuses on the relationship between neuronal metabolism and excitability to improve epilepsy treatment. … Drug-resistant epilepsy affects millions of people and one of the most effective treatments is dietary therapy that changes brain metabolism; however, the mechanism by which diet …
… , New York City, NY Glial control of neuron development and function Dr. Shaham’s work focuses on understanding the role of glia in nervous system development and function. The interplay between neurons and glia – which … develop and regulate synaptic function, how glia guide brain assembly, and how glia-dependent neurodegeneration …
… Postdoctoral Research Fellow in the McGovern Institute for Brain Research at Massachusetts Institute of Technology. In … the site-specific dopamine operations of the striatum and basal ganglia networks, as implicated in pathology. Dr. … in Electrical Engineering from Arizona State University and earned her M.S.E. in Electrical and Computer Engineering …
… 2015 Image Stanford University , Palo Alto, CA Regulation and Regeneration of Hippocampal Plasticity by Neural … researched the role for undifferentiated neural stem and progenitor cells in the adult brain after exercise (which is beneficial) and seizure (which …