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… His laboratory studies rapid plasticity of GABA and glutamate-mediated neurotransmission, and also focuses on regulation of seizures by hormonal … seizures using tools and technologies developed by the NIH BRAIN Initiative. This work could potentially open novel …
… Molecular mechanisms of axon guidance receptor regulation and signaling Dr. Bashaw studies how different types of neurons develop and organize into functional circuits. His research program … as they navigate to specific targets in the developing brain. Understanding the complexities of axon guidance …
… Cornell Medicine , New York, NY Ion Coupling, Permeation, and Regulation in Glutamate Transporters Dr. Boudker’s … contribute to cells’ interactions with the environment and how transporters move neurotransmitters from cell to … is critical for learning and cognition processes of the brain, and the role of ions in this process. The overarching …
… Image Emory University , Atlanta, GA Glutamate receptors and human neurological disease Dr. Traynelis’ lab will use electrophysiological, molecular, and structural approaches to probe multiple aspects of … component of excitatory synaptic transmission in the brain. The goal of this research is to gain insight into the …
… Wood’s research focuses on determining how growth factors and signaling pathways interact to promote growth, survival and differentiation of breast epithelial and neural … the downstream signaling pathways differ between the brain and spinal cord. Understanding the signaling pathways …
… 2020 Image University of North Carolina , Chapel Hill, NC Dr. Anton examines the cellular and molecular mechanisms …
… 2024 Image Columbia University , New York, NY Structure and function of ionotropic glutamate receptors Dr. … Sobolevsky’s research has focused on structural biology and electrophysiology and has made substantial contributions … receptors, which are important for mediating signal in the brain. Understanding the molecular basis of these iGluRs …
… of California , Los Angeles, CA Cell-specific mechanism and functional connectivity in TBI using optogenetic fMRI … underlying altered network connectivity in severe brain injury and impaired consciousness using fMRI. Dr. Crone completed …
… of Kentucky , Lexington, KY Dr. Gentry examines the nature and mechanisms of glycogen metabolism and how mis-regulation of these signaling events can lead to … (LD). Recent work suggests that glycogen aggregates in the brain may cause LD. For this proposal, he will use LD as an …
… 2019 Image Cornell University , Ithaca, NY New mechanisms and technologies for understanding post-transcriptional gene … epitranscriptomics – that is, the study of the role and function of mRNA base modifications. The lab also studies … of epitranscriptomic regulation of mRNA expression in the brain, the role of RNA-directed epigenetic silencing in …