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Notice the Discontinuation Participation NINDS PA-16-307 Ruth L. Kirschstein National Research Service Award NRSA) Individual Postdoctoral Fellowship Parent F32)" Notice Number: NOT-NS-17-002 Key Dates Release Date: October 17, 2016 Related Announcements PA-16-307 NOT-NS-16-012 NOT-NS-16-013     Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice informs community the National Institute Neurological Disorders Stroke NINDS) discontinue participation PA-16-307 quot;Ruth L. Kirschstein National Research Service Award NRSA) Individual Postdoctoral Fellowship Parent F32)".  NINDS not accept either new resubmission applications PA-16-307 the December 8, 2016 application due date beyond. NINDS now accepting applications F32 support exclusively via PAR-16-458. previously described NOT-NS-16-012 NOT-NS-16-013, NINDS restructuring funding support postdoctoral researchers.  Beginning the December 8, 2016 due date, research training support postdoctoral fellows under F32 activity code be available through NINDS using PAR-16-458 quot;NINDS Ruth L. Kirschstein National Research Service Award NRSA) Training Postdoctoral Fellows F32)."  NINDS F32 support postdocs are within first 3 years research training the sponsor's laboratory, includes several key differences the parent F32. Most notably, applicants only eligible the NINDS F32 prior starting, within first 12 months starting, postdoctoral training the sponsor's laboratory research environment. Because the very early application, preliminary data expected.  is anticipated another Funding Opportunity Announcement postdocs, utilizes K01 activity code, be published time the February 12, 2017 initial receipt date. will available applicants their second through fourth year cumulative postdoctoral research experience NOT-NS-16-013).  Inquiries Please direct inquiries to: Stephen Korn, Ph.D. National Institutes Neurological Disorders Stroke Telephone: 310-496-4188 Email: korns@ninds.nih.gov

Notice Correction the Application Due Date RFA-NS- 17-002 High Impact Neuroscience Research Resource Grants R24)" Notice Number: NOT-NS-17-001 Key Dates Release Date: October 6, 2016 Related Announcements RFA-NS-17-002 Issued National Institute Neurological Disorders Stroke NINDS)  Purpose purpose this Notice to correct Application due date RFA-NS-17-002, quot;High Impact Neuroscience Research Resource Grants R24)". application due date the FOA, February 14, 2016 incorrect. correct date February 14, 2017. nbsp; current version the FOA reads: Part 1. Key Dates Open Date Earliest Submission Date):          January 14, 2016 Letter Intent Due Date(s):                            January 14, 2016 Application Due Date(s):                                  February 14, 2016 FOA corrected read: Part 1. Key Dates Open Date Earliest Submission Date):           January 14, 2017 Letter Intent Due Date(s):                            January 14, 2017 Application Due Date(s):                                  February 14, 2017, nbsp; other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Randall R. Stewart, Ph.D.  National Institute Neurological Disorder Stroke NINDS) Telephone: 301-496-1917  Email: stewartr@mail.nih.gov

Notice Extend RFA-MH-17-245 BRAIN Initiative: Non-Invasive Neuromodulation - Mechanisms Dose/Response Relationships Targeted CNS Effects R01)" Notice Number: NOT-MH-16-023 Key Dates Release Date: September 16, 2016 Related Announcements RFA-MH-17-245 Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose purpose this Notice to extend RFA-MH-17-245 ldquo;BRAIN Initiative: Non-Invasive Neuromodulation - New Tools Techniques Spatiotemporal Precision R01)" invites application encourage optimization existing electrical magnetic stimulation methods. Part 1. Key Dates Currently reads:  Application Due Date(s): November 23, 2016 Scientific Merit Review: March 2017 Advisory Council Review: 2017 Earliest Start Date: September 2017 Expiration Date: November 24, 2016 Modified read: Application Due Date(s): November 23, 2016 October 13, 2017 Scientific Merit Review: March 2017 March 2018 Advisory Council Review: 2017 May 2018 Earliest Start Date: September 2017 September 2018 Expiration Date: October 14, 2017 other aspects this FOA remain same. Inquiries Please direct inquiries to: Fred Friedman, Ph.D. National Institute Mental Health NIMH) Telephone: 301-443-4058 Email: ffriedma@mail.nih.gov

Notice Extend RFA-MH-17-240 BRAIN Initiative: Non-Invasive Neuromodulation - New Tools Techniques Spatiotemporal Precision R01)" Notice Number: NOT-MH-16-024 Key Dates Release Date: September 16, 2016 Related Announcements RFA-MH-17-240 Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose purpose this Notice to extend RFA-MH-17-240 ldquo;BRAIN Initiative: Non-Invasive Neuromodulation - New Tools Techniques Spatiotemporal Precision R01)" invites application develop test novel tools methods neuromodulation go beyond existing variations. Part 1. Key Dates Currently reads:  Application Due Date(s): November 23, 2016 Scientific Merit Review: March 2017 Advisory Council Review: 2017 Earliest Start Date: September 2017 Expiration Date: November 24, 2016 Modified read: Application Due Date(s): November 23, 2016 October 13, 2017 Scientific Merit Review: March 2017 March 2018 Advisory Council Review: 2017 May 2018 Earliest Start Date: September 2017 September 2018 Expiration Date: October 14, 2017 other aspects this FOA remain same. Inquiries Please direct inquiries to: Fred Friedman, Ph.D. National Institute Mental Health NIMH) Telephone: 301-443-4058 Email: ffriedma@mail.nih.gov

Notice Extend RFA-MH-17-235 BRAIN Initiative: Foundations Non-Invasive Functional Human Brain Imaging Recording-Bridging Scales Modalities R01)" Notice Number: NOT-MH-16-025 Key Dates Release Date: September 16, 2016 Related Announcements RFA-MH-17-235 Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose purpose this Notice to extend RFA-MH-17-235 ldquo;BRAIN Initiative: Foundations Non-Invasive Functional Human Brain Imaging Recording - Bridging Scales Modalities R01)" invites application support effort will revolutionize our understanding the biological activity underlying, bioinformatic content data collected using contemporary non-invasive functional brain imaging techniques.  Part 1. Key Dates Currently reads:   Application Due Date(s): November 23, 2016 Scientific Merit Review: March 2017 Advisory Council Review: 2017 Earliest Start Date: September 2017 Expiration Date: November 24, 2016 Modified read: Application Due Date(s): November 23, 2016 October 13, 2017 Scientific Merit Review: March 2017 March 2018 Advisory Council Review: 2017 May 2018 Earliest Start Date: September 2017 September 2018 Expiration Date: October 14, 2017 other aspects this FOA remain same. Inquiries Please direct inquiries to: Jay Churchill, Ph.D. National Institute Mental Health NIMH) Telephone: 301-443-3621 Email: churchillj@mail.nih.gov

Notice Extend RFA-MH-17-220 BRAIN Initiative: Development Validation Novel Tools Analyze Cell-Specific Circuit-Specific Processes the Brain R01)" Notice Number: NOT-MH-16-026 Key Dates Release Date: September 16, 2016 Related Announcements RFA-MH-17-220 Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose purpose this Notice to extend RFA-MH-17-220 ldquo;BRAIN Initiative: Development Validation Novel Tools Analyze Cell-Specific Circuit-Specific Processes the Brain R01)" invites application develop validate novel tools facilitate detailed analysis complex circuits provide insights cellular interactions underlie brain function. Part 1. Key Dates Currently reads: Application Due Date s): November 2, 2016 Scientific Merit Review: March 2017 Advisory Council Review: 2017 Earliest Start Date: September 2017 Expiration Date: November 3, 2016 Modified read: Application Due Date(s): November 2, 2016 October 13, 2017 Scientific Merit Review: March 2017 March 2018 Advisory Council Review: 2017 May 2018 Earliest Start Date: September 2017 September 2018 Expiration Date: October 14, 2017 other aspects the FOA remain unchanged. Inquiries Please direct inquiries to: Michelle Freund, Ph.D. National Institute Mental Health NIMH) Telephone: 301-443-1815 Email: BRAIN-info-NIMH@mail.nih.gov

BRAIN Initiative Multi-Council Working Group Clearance Initiative Concepts FY2017 Notice Number: NOT-NS-16-041 Key Dates Release Date: September 6, 2016 Related Announcements None     Issued National Institute Neurological Disorders Stroke NINDS) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Mental Health NIMH) National Center Complementary Integrative Health NCCIH) Purpose Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative an ambitious multi-agency effort announced President Obama April 2013. Specific goals NIH contributions the Initiative formulated over year-long planning process culminated the release BRAIN 2025: Scientific Vision, seminal planning document produced a working committee the Advisory Council the NIH Director. NIH continues be guided this document by input the BRAIN Multi-Council Working Group MCWG), committee includes Advisory Council members each the ten NIH Institutes Centers ICs) contributing the BRAIN Initiative.  upcoming fiscal year represents transition point the BRAIN Initiative, goals scaling efforts a number specific areas: 1.  Census Brain Cell Types 2.  Tools Cells Circuits 3.  Technologies Neural Recording Modulation 4.  Human Imaging Neuromodulation 6.  Technology Dissemination Training 7.  Small Business Awards 8.  Data Coordination 9.  Neuroethics fund ambitious goals this transition, President’s budget calls a total appropriation 195 million, has matched exceeded proposals House Senate appropriations subcommittees.  its most recent meeting August 2, 2016, MCWG provided clearance BRAIN FY 2017 initiatives.  Investigators interested particular research areas encouraged review listing cleared initiatives, includes contact information NIH Program staff each area.  Links this information be found the following url:  https://braininitiative.nih.gov/about/multi-council-working-group. Interested parties also encouraged subscribe the BRAIN Update post https://brainupdate.nih.gov/), issues periodic announcements including new funding opportunities.  Inquiries Please direct inquiries to: Edmund Ned) Talley, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1917 Email: Edmund.Talley@nih.gov email strongly preferred) Gregory K. Farber, Ph.D. National Institute Mental Health NIMH) Telephone:  301-435-0778 Email: farberg@mail.nih.gov

Notice Discontinuation PAR-14-340 Request Access Parkinson's Disease Related-Biospecimens X01)" Notice Number: NOT-NS-16-040 Key Dates Release Date: August 2, 2016 Related Announcements PAR-14-340 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to inform potential applicants NINDS discontinue PAR-14-340 quot;Request Access Parkinson's Disease Related-Biospecimens X01)" of August 12, 2016. Information the Parkinson's Disease Biomarkers Program PDBP), the continued coordination biosample access various Parkinson's Disease cohorts including PDBP, BioFIND NINDS/Michael J. Fox Foundation MJFF) collaboration), Harvard Biomarker Study, and  MJFF supported resources including DATATOP, LRRK2 cohort the 24 hour biofluid sampling study available the PDBP biospecimen website. Inquiries Please direct inquiries to: Margaret Sutherland, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email: sutherlandm@ninds.nih.gov nbsp;

Notice a Webinar Presentation the NINDS Countermeasures Against Chemical Threats CounterACT) Funding Opportunity Announcements Notice Number: NOT-NS-16-037 Key Dates Release Date:   July 28, 2016 Related Announcements PAR-15-315 PAR-16-329 PAR-16-330 PAR-16-331 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to alert community the Countermeasures Against Chemical Threats CounterACT) program posted narrated presentation webinar) describing current Funding Opportunity Announcements supported the program.   After reviewing presentation, potential CounterACT applicants encouraged submit any questions comments may via email the point contact below. Depending the nature specifics the inquiries, may included the list Frequently Asked Questions FAQs) already the CounterACT website inform general community. Participation this webinar, although encouraged, optional is required the submission an application response these FOAs. Inquiries Please direct inquiries to: Shardell M. Spriggs, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone:  301-443-8189 Email:  shardell.spriggs@nih.gov

NINDS Policy Submission Applications Containing Clinical Trials Notice Number: NOT-NS-16-034 Key Dates Release Date:   July 20, 2016 Rescinded - April 03, 2018) Related Announcements Notice replaces NOT-NS-13-006 PA 16-160 PA-16-161   Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to define types clinical studies may submitted NINDS response the NIH parent R01 R21 Funding Opportunity Announcements FOAs) PA 16-160 PA-16-161, subsequent reissuances these FOAs.  NINDS not accept investigator-initiated R01 R21 applications include clinical trials under PA 16-160 PA-16-161.  clinical trial a prospective biomedical behavioral research study human subjects designed answer specific questions the safety, tolerability, efficacy and/or effectiveness pharmacologic, behavioral, biologic, surgical, device invasive non-invasive) interventions.  policy does apply 1) NINDS-specific announcements specifically solicit clinical trials, 2) exploratory IND studies defined the FDA http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformat…) 3) early feasibility studies devices defined the FDA http://www.fda.gov/downloads/medicaldevices/deviceregulationandguidance…). Applicants submitting investigator-initiated applications NINDS contain clinical trial must submit one the following NINDS FOAs specifically designed clinical trials: NINDS Exploratory Clinical Trials R01) PAR 13-281 NINDS PHASE III Investigator-Initiated Multi-Site Clinical Trials U01) PAR 13-278 the subsequent reissuance these FOAs. Inquiries Please direct inquiries to: Peter Gilbert, Sc.M. National Institute Neurological Disorders Stroke Telephone: 301-496-0870 Email: GilbertP@ninds.nih.gov