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Expert Panel Meeting Discuss Study Design a Longitudinal Study the Impact Prenatal Opioid other Substance Exposure Brain Behavioral Development Notice Number: NOT-DA-18-047 Key Dates Release Date: October 19, 2018 Related Announcements None Issued National Institute Drug Abuse NIDA) National Institute Alcohol Abuse Alcoholism NIAAA) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Minority Health Health Disparities NIMHD) Purpose Problem Statement:  has a dramatic increase the number babies have prenatally exposed opioids due the opioid crisis. Between 2004 2014, number infants born neonatal opioid withdrawal syndrome NOWS; also known neonatal abstinence syndrome NAS]) increased 433% 1.5 8.0 per 1000 hospital births translates one neonate born NOWS every 15 minutes. the opioid crisis continues escalate, numbers also increase, we not know the long-term implications early exposure opioids to medications used treat opioid disorder) be. addition, drugs continue be used during pregnancy afterwards many women breastfeeding. National Survey Drug and Health indicates in 2016, 6.3% pregnant women used illicit drug Center Behavioral Health Statistics Quality, 2017), many used than drug. large growing body evidence indicates early exposure substances, including pre- perinatally, linked greater risk developing substance disorders. Prenatal exposure also associated other behavioral problems, including ADHD, conduct disorder, anxiety, etc. However, causal link difficult establish due confounding factors such socioeconomic, environmental, genetic influences. Thus, meeting being convened discuss research needs understand disentangle complex interrelated factors may impact long-term consequences pre- perinatal substance exposure.   Key research objectives include, are limited to: Understanding variability individual developmental trajectories e.g., brain, cognitive, emotional, social, academic) birth through childhood. Understanding impact pre- postnatal exposure opioids, opioid treatment medications, cannabis, alcohol, tobacco, prescription illicit substances alone in combination) developmental trajectories. Investigating role sex, genetic, epigenetic, social other environmental factors risk/resilience related structural functional brain development, social/behavioral/academic achievement, future substance and mental disorders.  goal this meeting to discuss study design related issues e.g., sampling strategy, recruitment retention high risk populations, bioethical social service implications) a longitudinal study the impact pre- postnatal substance exposure including opioids, opioid treatment medications, cannabis, alcohol, tobacco, prescription illicit substances, alone in combination) brain development, mental illness, substance use, social/behavioral/academic achievement. is envisioned successful execution a program this breadth depth require broad interdisciplinary team investigators collective expertise pregnancy, neonatal, early childhood affective, cognitive, social development; longitudinal cohort studies; developmental neuroimaging; social/legal environmental issues. Input advice the extramural community be actively encouraged through multiple mechanisms.  NIH hold workshop October 22, 2018 at 6001 Executive Blvd Bethesda MD 20892, is open the public, although seating limited.  meeting also webcast. more information see https://www.drugabuse.gov/news-events/meetings-events. will followed a formal Request Information potential issues such study.   Inquiries Please direct inquiries to: Gayathri J. Dowling, Ph.D. Director, Adolescent Brain Cognitive Development ABCD) Study National Institute Drug Abuse Telephone: 301-443-4877 Email: gayathri.dowling@nih.gov

Request Information RFI) the Proposed Funding Priorities Neuroscience Research, Input Cross-Cutting Opportunities NIH Neuroscience Blueprint) Notice Number: NOT-NS-19-002 Key Dates Release Date:October 17, 2018 Related Announcements None Issued NIH Blueprint Neuroscience Research ( http://neuroscienceblueprint.nih.gov) National Institute Neurological Disorders Stroke ( NINDS) National Eye Institute ( NEI) National Institute Aging ( NIA) National Institute Alcohol Abuse Alcoholism ( NIAAA) National Institute Biomedical Imaging Bioengineering ( NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development ( NICHD) National Institute Dental Craniofacial Research ( NIDCR) National Institute Drug Abuse ( NIDA) National Institute Environmental Health Sciences ( NIEHS) National Institute Mental Health ( NIMH) National Institute Nursing Research ( NINR) National Center Complementary Integrative Health ( NCCIH) Office Behavioral Social Sciences Research ( OBSSR)  Purpose National Institutes Health Blueprint Neuroscience Research Blueprint) a collaboration among 14 participating NIH Institutes, Centers Offices support cross-cutting funding programs advance research the nervous system. Request Information RFI) seeks input the scientific community future Blueprint activities. Responses this RFI should suggest best have broadest possible impact the neuroscience community, ideally, a value-added fashion over current activities the participating Institutes, Centers Offices. Recommendations should serve interests many the Blueprint Institutes listed above. Blueprint invites input all interested stakeholders. Organizations encouraged submit single representative response. Background Neuroscience research a unifying theme across NIH Institutes Centers. Sixteen participating Institutes Centers launched Blueprint 2004 provide framework coordinating research developing tools resources broadly advance neuroscience research. pooling resources expertise, NIH Blueprint taking advantage economies scale, confronting challenges too large any single NIH Institute Center IC), harmonizing related efforts across multiple ICs. following website provides overview previous current NIH Blueprint Activities: http://www.neuroscienceblueprint.nih.gov/. Information Requested Blueprint considering best advance neuroscience the future. the establishment funding the BRAIN Initiative, focuses development application innovative technologies interrogating circuit activity the nervous system, Blueprint hopes identify non-duplicative areas broad interest the neuroscience community will the highest potential advance neuroscience via investment cross-cutting research, training, infrastructure and/or workforce development. Keeping mind the Blueprint interested ideas are broadly relevant across multiple missions the 14 participating NIH Institutes Centers, comments the RFI include are limited the following areas: Please submit specific suggestions how NIH Blueprint enhance neuroscience training workforce diversity going forward. Please submit suggestions infrastructure research resources needs cut across NIH neuroscience Institutes Centers would best serviced a Blueprint program. addition to training diversity efforts, Blueprint previously supported programs address cross-cutting issues such as: computational neuroscience research, dissemination of neuroscience tools to advance science, supporting core facilities Please submit thoughts how efforts been useful.  Please submit suggestions specific ways which programs should expanded. Please identify specific scientific areas neuroscience research specific research topics are currently being supported the BP Institutes, Centers Offices would of broad interest impact. Please suggest level budgetary investment be needed make significant difference that research area over five-year period. Please identify specific impediments advancing our understanding neuroscience a Blueprint supported program solve. to Submit Response comments must submitted electronically to: NIH-Blueprint-Responses. Responses this RFI be accepted through November 26, 2018. will receive electronic confirmation acknowledging receipt your response will receive individualized feedback any suggestions. Disclaimer RFI is information planning purposes only should be construed a solicitation as obligation the part the Federal Government, National Institutes Health NIH), individual NIH Institutes Centers. NIH does intend make any awards based responses this RFI pay the preparation any information submitted for Government's of such information. basis claims against U.S. Government shall arise a result a response this request information from Government’s of such information. NIH use information submitted response this RFI its discretion will provide comments any responder’s submission. However, responses the RFI be reflected future planning activities funding opportunity announcements. information provided be analyzed may appear reports. Respondents advised the Government under obligation acknowledge receipt the information received provide feedback respondents respect any information submitted. proprietary, classified, confidential, sensitive information should included your response. Government reserves right use any non-proprietary technical information any resultant solicitation(s). Inquiries Please direct inquiries to: Meghan Mott, Ph.D. National Institute Neurological Disorders Stroke ( NINDS) Telephone: 301-596-4470 Email: nihblueprint@nih.gov

Notice Clarification: Research Strategy page limit RFA-NS-18-046 Analytical and/or Clinical Validation a Candidate Biomarker Pain R61/R33 Clinical Trial Optional) Notice Number: NOT-NS-19-004 Key Dates Release Date:October 15, 2018 Related Announcements PAR-18-550 PAR-18-664 PAR-18-548 PAR-18-549  RFA-NS-18-046 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to clarify Research Strategy page limit RFA-NS-18-046, Analytical and/or Clinical Validation a Candidate Biomarker Pain R61/R33 Clinical Trial Optional). Research Strategy section page limit been increased 12 20 pages allow additional space materials are disallowed the Appendix. Figures, tables, graphs, diagrams, data, charts are necessary support proposal should included the Research Strategy section, these not appropriate the Appendix. not the Appendix circumvent page limits. Allowable Appendix Materials, follow instructions the Appendix described the SF424 R&R) Application Guide. Allowable Appendix Materials restricted. Please the NIH Guide Notice on Allowable Appendix Materials and the FAQs the NIH Appendix Policy for information.  an application submitted disallowed materials the Appendix will withdrawn noncompliance. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Mary Ann Pelleymounter, PhD  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1779  Email:  mary.pelleymounter@nih.gov

Notice Clarification: Research Strategy page limit PAR-18-548, Clinical Validation a Candidate Biomarker Neurological Disease U44 Clinical Trial Optional) Notice Number: NOT-NS-19-005 Key Dates Release Date:October 15, 2018 Related Announcements PAR-18-550 PAR-18-664 PAR-18-548 PAR-18-549 RFA-NS-18-046 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to clarify Research Strategy page limit PAR-18-548, Clinical Validation a Candidate Biomarker Neurological Disease U44 Clinical Trial Optional). Research Strategy section page limit been increased 12 20 pages allow additional space materials are disallowed the Appendix. Figures, tables, graphs, diagrams, data, charts are necessary support proposal should included the Research Strategy section, these not appropriate the Appendix. not the Appendix circumvent page limits. Allowable Appendix Materials, follow instructions the Appendix described the SF424 R&R) Application Guide. Allowable Appendix Materials restricted. Please the NIH Guide Notice on Allowable Appendix Materials and the FAQs the NIH Appendix Policy for information.  an application submitted disallowed materials the Appendix will withdrawn noncompliance. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Mary Ann Pelleymounter, PhD  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1779  Email:  mary.pelleymounter@nih.gov

Notice Clarification: Research Strategy page limit PAR-18-664, Clinical Validation a Candidate Biomarker Neurological Disease U01 Clinical Trial Optional) Notice Number: NOT-NS-19-006 Key Dates Release Date:October 15, 2018 Related Announcements PAR-18-550 PAR-18-664 PAR-18-548 PAR-18-549 RFA-NS-18-046 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to clarify Research Strategy page limit PAR-18-664, Clinical Validation a Candidate Biomarker Neurological Disease U01 Clinical Trial Optional). Research Strategy section page limit been increased 12 20 pages allow additional space materials are disallowed the Appendix. Figures, tables, graphs, diagrams, data, charts are necessary support proposal should included the Research Strategy section, these not appropriate the Appendix. not the Appendix circumvent page limits. Allowable Appendix Materials, follow instructions the Appendix described the SF424 R&R) Application Guide. Allowable Appendix Materials restricted. Please the NIH Guide Notice on Allowable Appendix Materials and the FAQs the NIH Appendix Policy for information.  an application submitted disallowed materials the Appendix will withdrawn noncompliance. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Mary Ann Pelleymounter, PhD  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1779  Email:  mary.pelleymounter@nih.gov

Notice Clarification: Research Strategy page limit PAR-18-550, Analytical Validation a Candidate Biomarker Neurological Disease U01) Clinical Trial Optional) Notice Number: NOT-NS-19-007 Key Dates Release Date:October 15, 2018 Related Announcements PAR-18-550 PAR-18-664 PAR-18-548 PAR-18-549 RFA-NS-18-046 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to clarify Research Strategy page limit PAR-18-550, Analytical Validation a Candidate Biomarker Neurological Disease U01) Clinical Trial Optional). Research Strategy section page limit been increased 12 20 pages allow additional space materials are disallowed the Appendix. Figures, tables, graphs, diagrams, data, charts are necessary support proposal should included the Research Strategy section, these not appropriate the Appendix. not the Appendix circumvent page limits. Allowable Appendix Materials, follow instructions the Appendix described the SF424 R&R) Application Guide. Allowable Appendix Materials restricted. Please the NIH Guide Notice on Allowable Appendix Materials and the FAQs the NIH Appendix Policy for information.  an application submitted disallowed materials the Appendix will withdrawn noncompliance. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Mary Ann Pelleymounter, PhD  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1779  Email:  mary.pelleymounter@nih.gov

Notice Clarification: Research Strategy page limit PAR-18-549, Analytical Validation a Candidate Biomarker Neurological Disease U44 Clinical Trial Optional) Notice Number: NOT-NS-19-008 Key Dates Release Date:October 15, 2018 Related Announcements PAR-18-550 PAR-18-664 PAR-18-548 PAR-18-549 RFA-NS-18-046 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice to clarify Research Strategy page limit PAR-18-549, Analytical Validation a Candidate Biomarker Neurological Disease U44 Clinical Trial Optional). Research Strategy section page limit been increased 12 20 pages allow additional space materials are disallowed the Appendix. Figures, tables, graphs, diagrams, data, charts are necessary support proposal should included the Research Strategy section, these not appropriate the Appendix. not the Appendix circumvent page limits. Allowable Appendix Materials, follow instructions the Appendix described the SF424 R&R) Application Guide. Allowable Appendix Materials restricted. Please the NIH Guide Notice on Allowable Appendix Materials and the FAQs the NIH Appendix Policy for information. If application submitted disallowed materials the Appendix will withdrawn noncompliance. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Mary Ann Pelleymounter, PhD  National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1779  Email:  mary.pelleymounter@nih.gov

BRAIN Initiative: Notice Support Research the Fundamental Neurobiology Endogenous Opioid Systems Notice Number: NOT-DA-18-046 Key Dates Release Date:October 9, 2018 Related Announcements None Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose Brain Research through Advancing Innovative Neurotechnologies BRAIN) Initiative aimed revolutionizing neuroscience through development application innovative technologies map neural circuits, monitor modulate activity, understand they contribute thoughts, sensations, emotions behavior.  NIH issued variety Funding Opportunity Announcements FOAs) will support projects apply technologies understand neural circuit function the context specific circuits, resulting a diverse portfolio research the fundamental biology nervous system function.   announcement to inform research community NIH welcomes applications leverage tools technology emerging the BRAIN Initiative towards elucidating mechanisms which endogenous opioid systems regulate sensory processing, affect cognition appropriate the goals requirements specific BRAIN Initiative FOAs.  overuse opioids created public health crisis, the NIH responding this crisis through conventional Institute Center appropriations special programs such the HEAL Initiative .  However, because BRAIN Initiative specifically aims understand neural circuit activity translates sensory, emotional cognitive functions opioids produce effects engaging endogenous opioid circuits normally regulate same functions, BRAIN uniquely positioned advance knowledge this area. Examples research could supported include use the innovative tools technology profile transcriptome methylome opioid-related neurons , live imaging intracellular signaling cascades identify spatiotemporal aspects cellular signaling engaged opioid receptor activation, brain-wide optical imaging cellular activity cell-types engaged opioids under different conditions, changes connectivity network activity across trajectory opioid assessed optical imaging multiplexed high density electrophysiological recording. Because chronic opioid disrupts cognitive functions emotional regulation the extent being risk survival, study the opioid-dependent brain presents unique opportunity discover how  reprogramming neural substrates circuits translates reprogramming motivation, mood decision-making processes. Interested parties should check information goals requirements specific BRAIN FOAs may appropriate, contact Scientific/Program staff listed the text the respective announcements.  For list active upcoming FOAs, see https://braininitiative.nih.gov/funding/funding-opportunities.   Inquiries Please direct inquiries to: Olivier Berton, PhD National Institute Drug Abuse Telephone: 301) 827-7771 Email: olivier.berton@nih.gov

Collaborative Research Computational Neuroscience CRCNS) Innovative Approaches Science Engineering Research Brain Function Notice Number: NOT-MH-18-054 Key Dates Release Date:October 9, 2018 Related Announcements None Issued National Institute Mental Health NIMH) National Eye Institute NEI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Biomedical Imaging Bioengineering NIBIB) National Institute Deafness Other Communication Disorders NIDCD) National Institute Drug Abuse NIDA) National Institute Neurological Disorders Stroke NINDS) National Center Complementary Integrative Health NCCIH) Purpose Full Proposal Deadline(s) due 5 p.m. submitter's local time): November 27, 2018 Deadline FY 2019 competition November 25, 2019 Deadline FY 2020 competition Notice announces reissue a joint initiative, Collaborative Research Computational Neuroscience CRCNS), among six National Science Foundation NSF) Directorates Offices DOs), nine participating National Institutes Health NIH) Institutes Centers ICs). CRCNS announcement released underNSF 18-591. announcement supersedes NSF 18-501 NSF: Collaborative Research Computational Neuroscience CRCNS) Innovative Approaches Science Engineering Research Brain Function. NIH, CRCNS affiliated the NIH Blueprint Neuroscience Research (http://neuroscienceblueprint.nih.gov). Computational neuroscience provides theoretical foundation a rich set technical approaches understanding complex neurobiological systems, building the theory, methods, findings computer science, neuroscience, numerous disciplines. Through CRCNS program, National Science Foundation NSF), National Institutes Health NIH), German Federal Ministry Education Research Bundesministerium fr Bildung und Forschung, BMBF), French National Research Agency Agence Nationale de la Recherche, ANR), United States-Israel Binational Science Foundation BSF), Japans National Institute Information Communications Technology NICT), the State Research Agency Agencia Estatal de Investigacin, AEI) National Institute Health Carlos III Instituto de Salud Carlos III, ISCIII), both Spain, support collaborative activities will advance understanding nervous system structure function, mechanisms underlying nervous system disorders, computational strategies used the nervous system. classes proposals be considered response this solicitation: Research Proposalsdescribing collaborative research projects, Data Sharing Proposalsto enable sharing data other resources. Domestic international projects be considered. detailed the solicitation, international components collaborative projects be funded parallel the participating agencies. Specific CRCNS opportunities parallel funding available bilateral US-German Research Proposals, US-German Data Sharing Proposals, US-French Research Proposals, US-French Data Sharing Proposals, US-Israeli Research Proposals, US-Israeli Data Sharing Proposals, US-Japanese Research Proposals, US-Japanese Data Sharing Proposals, US-Spanish Research Proposals, US-Spanish Data Sharing Proposals, multilateral proposals involving United States two more CRCNS partner countries please Section VIII the solicitation country-specific instructions limitations). Appropriate scientific areas investigations be related the interests any the participating funding organizations. Questions concerning particular project's focus, direction, relevance a participating funding organization should addressed the appropriate person the list agency contacts found Section VIII the solicitation. NSF coordinate manage review proposals jointly participating domestic foreign funding organizations, through joint panel review process used all participating funders.Additional information available Section VI the solicitation. Applications submitted response this solicitation not duplicate be substantially similar other applications concurrently under consideration other programs study sections across agencies, including those response NIH investigator-initiated lsquo;parent FOAs NIH BRAIN Initiative FOAs. Duplicate substantially similar applications be returned without review. AwardInformation in previous years, is anticipated a minimum 5 million be available year this competition, potentially 15 20 million annually, depending the quality proposals availability funds. Award sizes Research Projects both domestic international) expected range approximately 100,000 250,000 per year direct costs, durations three five years. awards be the smaller end this range. Proposers strongly discouraged requesting larger budgets are necessary the activities being proposed. Investigators contemplating four- five-year projects advised discuss project requirements the appropriate agency contact(s) before submitting. expected range award sizes applies the combined direct costs, expressed US Dollars, all components a collaborative project which funding being sought participating funders, including components inside outside the United States. expected range award sizes does include costs foreign travel international partnering institutions. International travel costs be expected vary depending the countries specific proposed activities could result combined direct costs exceed expected range. Awards Data Sharing Projects be scaled according the needs the project; typically, will smaller size research awards. Investigators encouraged discuss project requirements the CRCNS Program Coordinator - NSF before submitting. Estimated program budget, number awards, average award size duration subject the availability funds. Upon conclusion the review process, meritorious research proposals be recommended funding one more the participating funding organizations, the option the funders, the proposer. Subsequent grant administration procedures be accordance the individual policies the awarding agency. Further information agency processes agency-specific award information provided Section VI.B. Section VIII this solicitation. Eligibility Information May Submit Proposals: categories proposers eligible submit proposals the National Science Foundation identified theNSF Proposal amp; Award Policies amp; Procedures Guide(PAPPG), Chapter I.E. May Serve PI: are restrictions limits. Limit Number Proposals per Organization: are restrictions limits. Limit Number Proposals per PI Co-PI:2 response this solicitation, investigator participate PI co-PI inno than proposalsper review cycle. the event a PI co-PI does appear either these roles more two proposals, proposals include person a PI co-PI be returned without review. limit applies all PIs co-PIs, based inside outside the United States. Additional Eligibility Info: Proposal Limit:Proposals submitted response this solicitation not duplicate be substantially similar other proposals concurrently under consideration other programs study sections the participating agencies. Duplicate substantially similar proposals be returned without review. Budgetary Information Cost Sharing: Inclusion voluntary committed cost sharing prohibited. Indirect Cost F&A) Limitations: Foreign organizations do have current U.S. federally negotiated indirect cost rate(s) limited a de minimis indirect cost rate recovery 10% modified total direct costs. Foreign grantees have U.S. federally negotiated indirect cost rate(s) recover indirect costs the current negotiated rate. Budgetary Limitations: Budgets should include travel funds the PI attend annual CRCNS Principal Investigators' meeting NIH Process those proposals are selected potential funding participating NIH Institutes Centers, PI be required resubmit proposal an NIH-approved format directly the Center Scientific Review (http://www.csr.nih.gov/) the NIH. PIs invited resubmit NIH receive further information resubmission procedures NIH. applicant not allowed increase proposed budget change scientific content the application the resubmission the NIH. NIH budgets not exceed 250,000 direct costs, the total direct costs requested the years not exceed total requested the NSF application. However, some cases, NIH Institutes request the budget request reallocated across years the grant conform NIH modular budget practices. Indirect costs any foreign subawards/subcontracts be limited eight 8) percent. Applicants be expected utilize Multiple Principal Investigator option the NIH (http://grants.nih.gov/grants/multi_PI/) appropriate. NIH applications be entered the NIH IMPAC II system. results the review be presented the involved Institutes' Centers' National Advisory Councils the second level review. Subsequent the Council reviews, NIH Institutes Centers make funding determinations selected awards be made. Subsequent grant administration procedures NIH awardees, including those related New Early Stage Investigators (http://grants.nih.gov/grants/new_investigators/), be accordance the policies NIH. Applications selected NIH funding use NIH R01 funding mechanism. the end the project period, renewal applications projects funded the NIH expected be submitted directly the NIH Renewal Applications, rather as proposals the CRCNS program. Principal Investigators should contact NIH Program Officer additional information. Inquiries Please direct inquiries to: Written telephone inquiries encouraged. Please the NSF program announcement names contact information each the participating NSF DOs and/or NIH ICs athttps://www.nsf.gov/publications/pub_summ.jsp?ods_key=nsf18591&org=NSF

Notice Encourage Eligible NINDS Alzheimer?s Disease Alzheimer?s Disease-Related Dementias AD/ADRD) Initiative Awardees Apply PA-18-906 Research Supplements Promote Diversity Health-Related Research" Notice Number: NOT-NS-19-003 Key Dates Release Date:October 1, 2018 Related Announcements PA-18-906 Issued National Institute Neurological Disorders Stroke NINDS) Purpose Notice encourages eligible NINDS awardees the Alzheimers Disease Alzheimers Disease-Related Dementias AD/ADRD) research community apply administrative supplements response toPA-18-906, Research Supplements Promote Diversity Health-Related Research." NIH a strong interest the diversity the NIH-funded workforce seeNOT-OD-18-210for details) encourages institutions diversify student populations enhancing participation individuals groups are underrepresented the biomedical, clinical, behavioral, social sciences. Goal 1 TheNational Plan Address AlzheimersDiseaseis prevent effectively treat AD/ADRD 2015. initiative addresses critical need increase number health professionals are trained meet expanding demand cognitive impairment dementia diagnosis, care, clinical research meet Goal 1. Program Directors/Principal Investigators PD/PI) active AD/ADRD research grants thus encouraged identify eligible individuals, including those underrepresented groups, support mentorship under auspices this supplement opportunity. Individuals the identified groups eligible throughout training continuum high school the faculty level. activities proposed the supplement application must fall within scope advance objectives the parent grant, also support research training professional development the supplement candidate. PIs must reference Notice the cover letter application. further guidance submitting responsive NINDS diversity supplement please visit link:https://www.ninds.nih.gov/Funding/Training-Career-Development/Award/SUP…. Diversity supplement awardees, appropriate the duration their support career stage, request funds, addition the research costs specified inPA-18-906, enable supplement candidate attend AD/ADRD research summits the Washington, DC area. request additional funds should reasonable well justified the application. Applicants strongly encouraged consult the Program Official the parent grant the contact listed below before submitting application confirm eligibility to obtain technical assistance. Supplement requests under Notice submitted toPA-18-906)will undergo administrative evaluation NINDS staff, not full peer review. Eligible AD/ADRD research awardscan identified using NIH RePORTER by contacting Dr. Jordan Gladman via email. tracking, a diversity supplement application responsive this Notice submitted please email Dr. Jordan Gladman include PD/PI name grant number the subject line the email. Applications be considered according the following schedule: Application Due DateEarliest Funding Decision November 16, 2018 February 15, 2019 March 2019 February 16, 2019 15, 2019 June 2019 August 1, 2019 November 15, 2019 December 2019 November 16, 2019 February 15, 2020 March 2020 February 16, 2020 15, 2020 June 2020 Inquiries Please direct inquiries to: Jordan Gladman, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-5680 Email:jordan.gladman@nih.gov