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… which are energy factories found inside almost all the cells in the body. There are many types of mitochondrial … within the same family. In some individuals, the weakness is most prominent in the muscles that control eye and eyelid … include loss of appetite, vomiting, irritability, loss of head control and motor skills, continuous crying, and …
… On this page What is functional neurologic disorder? Functional neurologic disorder (FND) refers to a … of the brain itself, as seen in many other neurological disorders. Physical symptoms of FND are genuine but cannot be … children and adults. Most people with functional movement disorders begin to have symptoms around their late 30s. …
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Alzheimer's Disease and Alzheimer's-Related Dementias
NINDS-led programs that advance Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD) research, as part of the National Plan to Address Alzheimer's Disease.…
… lesions, low muscle tone, microcephaly (unusually small head), increased muscle tone or stiffness (spasticity), … syndrome can be associated with unusual development of the head, heart, face, arms, or legs, although some children may … The disorder results in extreme backward bending of the head combined with severe distortion of the spine. Most …
… FTD and other frontotemporal disorders are a common cause of early-onset dementia. They often strike people in … language problems with the changes in the brain that cause them. Movement disorders Two rare neurological movement … associated with Alzheimer’s disease. In most cases, the cause of FTD is unknown. Individuals with a family history of …
… and the discovery of new biomarkers for Parkinson’s disease (PD). In July 2024, this effort moved into its second … the Accelerating Medicines Partnership(R) in Parkinson’s Disease and Related Disorders (AMP(R) PDRD). This partnership … for people living with these disorders. About Parkinson’s Disease and Related Disorders Parkinson’s disease is a …
… we launched a new feature on our website that shows how NINDS and the research we support contribute to the … we describe the more recent development of brain-targeted ERT for CLN2 disease, a form of Batten … to try treating Gaucher disease with gene therapy, which would allow patients to produce functional enzyme on their …
Repeat Expansion Disorder Biosample AccessInvestigators interested in obtaining Repeat Expansion Disorder biospecimens should submit their application through the NINDS biosample online submission webform, which also details the application requirements. Requests are reviewed by the Repeat Expansion Disorders Resource Access Committee (RED-BRAC), an external…
… disorders, and an RNA-targeting treatment for spinal muscular atrophy (SMA). All of these are examples of … disorders, and an RNA-targeting treatment for spinal muscular atrophy (SMA). …
… Friday, February 9, 2018 The toll that neurological disorders exact on patients and their families is truly … documenting the development of treatments for neurological disorders for which NINDS played a critical role. The first … in our shared mission to reduce the burden of neurological disorders. I invite you to learn more about the development …