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… Javits Award 2018 Image Mechanisms of Oligodendrocyte and Axonal Abnormalities After Perinatal Brain Injury Dr. Vittorio Gallo studies glial regulation of neural development and response to injury. For this project, he will study the …
… Role of mTOR Signaling in Oligodendrocyte Differentiation and CNS Myelination Dr. Wendy Macklin studies the process of … which is essential for normal nervous system development and function. Using rodent and zebrafish models, the goal of … the downstream signaling pathways differ between the brain and spinal cord. Understanding the signaling pathways …
… His laboratory studies rapid plasticity of GABA and glutamate-mediated neurotransmission, and also focuses on regulation of seizures by hormonal … seizures using tools and technologies developed by the NIH BRAIN Initiative. This work could potentially open novel …
… Molecular mechanisms of axon guidance receptor regulation and signaling Dr. Bashaw studies how different types of neurons develop and organize into functional circuits. His research program … as they navigate to specific targets in the developing brain. Understanding the complexities of axon guidance …
… Cornell Medicine , New York, NY Ion Coupling, Permeation, and Regulation in Glutamate Transporters Dr. Boudker’s … contribute to cells’ interactions with the environment and how transporters move neurotransmitters from cell to … is critical for learning and cognition processes of the brain, and the role of ions in this process. The overarching …
… Image Emory University , Atlanta, GA Glutamate receptors and human neurological disease Dr. Traynelis’ lab will use electrophysiological, molecular, and structural approaches to probe multiple aspects of … component of excitatory synaptic transmission in the brain. The goal of this research is to gain insight into the …
… Wood’s research focuses on determining how growth factors and signaling pathways interact to promote growth, survival and differentiation of breast epithelial and neural … the downstream signaling pathways differ between the brain and spinal cord. Understanding the signaling pathways …
… Carolina , Chapel Hill, NC Dr. Anton examines the cellular and molecular mechanisms underlying radial progenitor development, neuronal migration, and neuronal connectivity in the mammalian cerebral cortex. … processes can lead to neurodevelopmental disorders and brain malformations … …
… 2024 Image Columbia University , New York, NY Structure and function of ionotropic glutamate receptors Dr. … Sobolevsky’s research has focused on structural biology and electrophysiology and has made substantial contributions … receptors, which are important for mediating signal in the brain. Understanding the molecular basis of these iGluRs …
… of California , Los Angeles, CA Cell-specific mechanism and functional connectivity in TBI using optogenetic fMRI … underlying altered network connectivity in severe brain injury and impaired consciousness using fMRI. Dr. Crone completed …