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… Image NINDS established the Early Phase Pain Investigation Clinical Network (EPPIC-Net) as a part of … biologics, natural products, and devices, targeted to pain conditions of high unmet need. EPPIC-Net conducts … early phase clinical trials across the age and pain condition spectrum of pain therapeutics submitted by …
Monday, January 13, 2025
This past July, the Dr. Emmanuel Bilirakis and Honorable Jennifer Wexton National Plan to End Parkinson’s Act became law. This is an ambitious federal mandate to intensify efforts and coordinate our nation’s best resources to prevent, treat, or cure, and to improve quality of care for the millions of people affected by Parkinson’s disease (PD) and all other neurodegenerative Parkinsonisms. Recently, the U.S. Department of…
Monday, September 25, 2017
September is Pain Awareness Month. We all experience pain from time to time, but for many Americans pain is a chronic and difficult-to-treat condition. In my prior experience as a practicing neurologist, I witnessed the immense suffering that severe chronic pain causes. The most indelible memory is of a teenager with syringomyelia, a progressive enlargement of the spinal cord’s central canal, who was partially paralyzed but worse, experienced continuous severe burning pain. Imagine how…
… can require additional information prior to award. NOTE: What kind of foreign components are allowable and how these … being nested under a parent grant. A new award structure is being developed to support foreign subawards. Review the … policies at the link below. Latest on NIH Funding Policies What are foreign components? NIH defines a “foreign …
… referred to as Frontotemporal lobar degeneration (FTLD), is a clinically and pathologically heterogeneous group of … of the mechanisms underlying neurodegeneration in FTD. It is anticipated this initiative will help develop precision … & Disease Heterogeneity: Understand FTD epidemiology and how disease-modifying factors (genetic ancestry, environment, …
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What is corticobasal degeneration?Corticobasal degeneration (CBD) is a form of frontotemporal degeneration, a dementia that involves the loss of cognitive functions such as the ability to think, remember, or reason to the point that it interferes with a person's daily life and activities. CBD can affect:
- Movement
- Balance
- Coordination
- Memory
- Vision
- Speaking and swallowing
- Other bodily functions
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What is congenital myopathy?
Congenital myopathy is a term for any genetic muscle disorder that is typically noticed at birth and includes weakness and lack of muscle tone. Some congenital myopathies may not show symptoms until infancy or childhood. Myopathy happens when there is a problem with a muscle, a nerve that works with the muscle, or the brain itself. There are many types of congenital myopathy with varying severity. Some symptoms may remain stable or progress slowly. The following is a range of…
A realistic, targeted strategic recruitment and retention plan, adequately resourced, implemented and adjusted as needed, will have a significant impact on recruitment and retention, ensuring that your clinical trial can complete on time and have the intended impact.
Before you are funded:
Recruitment and retention planning are activities that should be done in parallel with grant writing and protocol design. Successful study recruitment and retention requires…
… Blepharospasm (BEB) is a neurological disorder that causes spasms, or twitching, of the eyelid. It is a form of … open, sometimes closed for long periods of time, which causes substantial visual disturbance or functional … Blepharospasm (BEB) is a neurological disorder that causes spasms, or twitching, of the eyelid. It is a form of …
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What is cytomegalovirus?
Cytomegalovirus (CMV) is a common virus that infects between 50 to 80 percent of all adults in the U.S. by age 40. CMV is in the same family of viruses that causes cold sores (herpes simplex virus), infectious mononucleosis (Epstein-Barr virus), and chickenpox/shingles (varicella zoster virus).
Some infants are infected with the virus before birth. Some people never develop symptoms. People with a compromised immune system may have more severe forms of infection involving the…