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Director's Overview
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Walter J. Koroshetz, M.D., Director
The mission of the National Institute of Neurological Disorders and Stroke (NINDS) is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to…
… References Overview Image NINDS Parkinson's disease (PD) is a neurodegenerative disorder that leads to resting tremor, … substantia nigra pars compacta (SNc), one of a group of brain structures known as the basal ganglia and part of a … Disease Study Group, Obeso JA, Olanow CW, Rodriguez-Oroz MC, Krack P, Kumar R, Lang AE. Deep-brain stimulation of the …
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Biosample AccessInvestigators interested in obtaining ME/CFS biospecimens should submit their application through the NINDS biosample online submission webform, which also details the application requirements. Requests are reviewed by the ME/CFS Biospecimen Resource Access Committee (ME/CFS BRAC), …
… first complete wiring diagram of neural connections in the brain, known as a connectome map, of the common fruit fly. … largest and most complete connectome of an adult animal brain created and provides critical information about how … wired, and the signals and connections needed for healthy brain function. In 1986, Sydney Brenner and colleagues …
Leukodystrophy Biosample AccessInvestigators interested in obtaining Leukodystrophy biospecimens should submit their application through the NINDS biosample online submission webform, which also details the application requirements. Requests are reviewed by the Leukodystrophy Biospecimen Resource Access Committee (LD-BRAC), an…
… concept describes the basic purpose, scope, and objectives of a potential solicitation of grants or contracts. Approved … Human Biospecimen and Data Repository (BioSEND) Rebecca Price This concept aims to provide a resource for … focusing on atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy (CAA), as well as how these …
… ataxias? Spinocerebellar ataxias (SCA) refer to a group of rare, genetic neurological disorders that cause loss of muscle control, coordination, and balance. The SCAs involve loss of structure and function (degeneration) of the cells of the hindbrain, which includes the cerebellum (the part that helps control …
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What is Tourette syndrome?Tourette syndrome (TS) is a neurological disorder that may cause sudden unwanted and uncontrolled rapid and repeated movements or vocal sounds called tics. TS is one of a group of disorders of the developing nervous system called tic disorders.The motor (involving body movement) or vocal (involving sounds you make) tics of TS come and go over time, varying in type, frequency, location, and severity. If you have tics, you cannot stop your body from having them. The first symptoms usually…
… On this page What is Angelman syndrome? Angelman syndrome is a genetic … laughter A small head size (microcephaly) Often, there are also gastrointestinal, orthopedic, and eye problems. … and motor problems. They still will understand much of what is said. They also often learn to communicate …
… the eyelid. It is a form of dystonia, a movement disorder in which muscle contractions cause twitching or repetitive … usually happen during the day and disappear when sleeping at night. BEB can affect men and women but is more common in middle-aged and older women. BEB is a …