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… for some earlier phase trials (e.g., trials that involve multiple sites, pose significant risk to participants, are …
… disorder that happens in childhood. It is caused by the same bacteria that causes rheumatic fever. Rheumatic … can cause severe illness in the heart, joints, skin, and brain. SC affects girls more often than boys, and usually … for months. Some children with SC may have another episode of symptoms after the first illness. This usually happens one …
… devastating, complex, and heterogeneous neurodegenerative disease that affects the neurons that control voluntary … planning, execution, and communication of research. Who are people with lived experience (PWLE)? In the context of … lines for current and new diseases covered by the NINDS are continuing to be added. Image The iPSC …
… help build the pathways—called neural circuits—that act as information highways between different areas of the brain. … areas of misplaced or oddly formed neurons that can cause disorders like childhood epilepsy. Some researchers think … lives of some neurons can take strange turns. Some diseases of the brain are the result of the unnatural deaths …
… Epilepsy Therapy Screening Program (ETSP)). R&D contracts do not include grants or cooperative agreements or other … the requirements and are able to fully respond. Learn how NINDS uses the electronic Contract Proposal Submission … determine where they did not match the Institute’s needs. Much of the information involved in reviewing contracts is …
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What are transmissible spongiform encephalopathies?Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of rare, degenerative brain disorders. Spongiform refers to the tiny holes that give the brain a "spongy" appearance in people with prion diseases. These holes can be seen when brain tissue is viewed under a microscope. TSEs cause problems with muscle coordination, thinking, and other symptoms. They tend to progress rapidly and usually cause death within a few months to a…
… On this page What is inclusion body myositis? Inclusion body myositis … diseases known as the inflammatory myopathies, which are characterized by chronic, progressive muscle inflammation … and supportive. However, IBM is generally resistant to all therapies and its rate of progression appears to be …
… of the National Institute of Neurological Disorders and Stroke (NINDS), NIH; Francis Collins, M.D., Ph.D., is the … ) … The National Institute of Neurological Disorders and Stroke (NINDS) highlights major progress in research on …
… and Endothelial Cell Interaction Epidemiology and Risk Factors Genetics Health Services Implementation Imaging … the value of imaging methods to provide direct comparisons between rodent and human brains. Multiphoton and other live … can control each other bi-directionally and hence their relationship is complex. In the developing brain, neural …
… On this page What is myotonia congenita? Myotonia congenita is an inherited neuromuscular disorder characterized by the inability of muscles to quickly …