Wireless Nerve Stimulation Device To Enhance Recovery After Stroke

Inclusion Criteria: In order to be eligible to participate in this study, an individual must meet all of the following criteria: - Provision of signed and dated informed consent form - Stated willingness to comply with all study procedures and availability for the duration of the study - Adult, aged 22-79 - Ischemic stroke that occurred ≥ 12 months prior to enrollment - UEFM score of 20 to 50 - Modified Rankin Score of 2, 3, or 4 - Right vocal cord has normal movement when assessed by laryngoscopy - Women of reproductive potential must use contraceptive protection - Meets all clinical criteria for the surgical VNS implantation as determined by the PI, surgeon, and anesthesiologist Exclusion Criteria: An individual who meets any of the following criteria will be excluded from participation in this study: - Deficits in language or attention that interfere with study participation - Severe spasticity (Modified Ashworth ≥ 3) - Medical or mental instability that would likely interfere with study protocol - Receiving any therapy (medication or otherwise) that would interfere with VNS, such as drugs that perturb neurotransmitter action (anticholinergics, adrenergic blockers, etc.) - Presence of any other implanted electrical stimulation device - Prior injury to vagus nerve - Lactating, pregnant, or plan to become pregnant - Participation in another interventional clinical trial - Clinical complications that hinder or contraindicate the surgical procedure - Abusive use of alcohol and/or illegal substances use - Active neoplastic disease. - Any medical condition or other circumstances that might interfere with their ability to return for follow-up visits in the judgment of the Investigator. - Any condition which, in the judgment of the Investigator, would preclude adequate evaluation of device's safety and performance. - Recent history of syncope - Recent history of dysphagia - Current or anticipated requirement for diathermy