PRIMARY OBJECTIVE: I. To estimate the risk of serious adverse events (SAE) related to intervention in asymptomatic SANCC; these include drug-related side effects, moderate/severe intracranial hypertension, hydrocephalus requiring shunting or endoscopy, stroke, status epilepticus, or unexplained death. OUTLINE: Participants will be hospitalized for approximately 15-30 days while they receive treatment with the antiparasitic drug albendazole, as well as additional drugs (dexmathesaone and omeprazole) to address potential treatment complications. Participants will have continuous monitoring for adverse events while in the hospital. After participants are released to home, they will monitored for adverse events for an additional 12 months through home visits, telephone contact, and monthly clinical evaluations with serologic and radiologic assessment.
Inclusion Criteria: - Male or female individuals older than two years with a diagnosis of asymptomatic SANCC confirmed by MRI. - SANCC limited to the basal cisterns, the interhemispheric brain space, brain fissures or spine. - Baseline laboratory results within acceptable ranges (specifically defined in the study protocol) - Willingness to accomplish the two-week minimum hospitalization required. Exclusion Criteria: - Individuals who only have subarachnoid lesions in the convexity of the brain hemispheres will not be included because these lesions commonly respond well to therapy and behave as intraparenchymal lesions - Co-occurrence of a) more than 20 intraparenchymal lesions in addition to their subarachnoid disease, or b) intraparenchymal lesions greater than 3.0 cm of diameter - Individuals for whom a surgical intervention to treat their subarachnoid disease is considered clearly superior to a medical intervention - Previously diagnosis or treatment for cysticercosis. - Active pulmonary tuberculosis evidenced by chest X-ray and positive sputum smears, or symptoms compatible with tuberculosis (fever+sweats or fever+cough) not otherwise explained - Individuals with positive markers for active hepatitis - Other systemic disease that may affect therapy or short-term prognosis, including but not limited to chronic renal failure, hepatic insufficiency, cardiac failure, or steroid-dependent immune diseases - Pregnancy. If a participant becomes pregnant during the study, she will continue in the study but will have radiological exams delayed until after delivery - History of hypersensitivity to ABZ - Chronic alcohol or drug abuse as defined in the study protocol - Unwilling or unable to provide MRI exams (e.g. patients with ferromagnetic implants) - Inability or unwillingness of subject or legal representative to give written informed consent.