This collaborative, international effort has one primary goal. This is to create a biospecimen repository and associated clinical database to be used as a resource for dystonia and related disease research. Across sites, the investigators hope to enroll at least 5,000 adult patients. Subjects of this study will be asked to complete a neurological exam which will be video recorded, complete some questionnaires, and donate a blood sample. A study visit will take between 45 minutes and 1 hour. All subjects will be asked to return every 1, 2, 3, or 4 years for a one hour follow-up visit. People may participate in this study without agreeing to participate in the follow-up visits.
Inclusion Criteria: - Diagnosed with isolated dystonia or myoclonus dystonia or dopa-responsive dystonia - To be included in laryngeal dystonia group, nasolaryngoscopy (voice box exam) must have been completed to confirm diagnosis (this voice box exam is not part of the study) Exclusion Criteria: - Any evidence of a secondary cause for dystonia (other than myoclonus dystonia or dopa-responsive dystonia) - Less than 2 months since last botulinum toxin injection - Inability to provide informed consent - Significant medical or neurological conditions that preclude completing the neurological exam - Significant physical or other condition that would confound diagnosis or evaluation, other than dystonia or tremor