Chart Review: Central Motor Conduction Time in Neurological Disorders

Objective- To retrospectively study the results of transcranial magnetic stimulation (TMS) in various neurological disorders and create a descriptive analysis of the results. Study population- Existing records of patients within the NINDS database who have had TMS performed to measure central motor conduction time (CMCT). Design- - Retrospective descriptive analysis. - The NINDS EMG Database will be queried using terms such as TMS, CMCT, and MEP (motor evoked potentials) to identify EMG reports on patients who underwent TMS for diagnosis - Within these reports peripheral motor conduction time (PMCT), the cortical motor evoked potential (MEP) latency and amplitude will be used to calculate CMCT, clinical patient factors pertinent to estimation of CMCT as well clinically significant physical exam findings will be recorded as well. - Clinical diagnoses and neurological exams will be extracted from medical records - Patient identifiers will be de-linked after compiling data from medical records Outcome measures - Results of CMCT using TMS in different diagnoses will be summarized for different neurologic disorders and correlated to clinical exam measures documented in previous records

- INCLUSION CRITERIA: 1. Patients who were seen in the NINDS EMG section for diagnostic TMS studies 2. Patients tested between 1998 and 2017 3. Greater than or equal to age 18.

Study Location
Maryland