Press Releases

Dormant viral genes may awaken to cause ALS

Wednesday, September 30, 2015

Scientists at the National Institutes of Health (NIH) discovered that reactivation of ancient viral genes embedded in the human genome may cause the destruction of neurons in some forms of amyotrophic lateral sclerosis (ALS).

Scientists uncover nuclear process in the brain that may affect disease

Monday, August 17, 2015

Every brain cell has a nucleus, or a central command station. Scientists have shown that the passage of molecules through the nucleus of a star-shaped cell, called an astrocyte, may play a critical role in health and disease. The study, published in the journal Nature Neuroscience, was partially...

Neurons' broken machinery piles up in ALS

Wednesday, August 12, 2015

A healthy motor neuron needs to transport its damaged components from the nerve-muscle connection all the way back to the cell body in the spinal cord. If it cannot, the defective components pile up and the cell becomes sick and dies.

PINK1 protein crucial for removing broken-down energy reactors

Wednesday, August 12, 2015

Cells are powered by tiny energy reactors called mitochondria. When damaged, they leak destructive molecules that can cause substantial harm and eventually kill brain cells. Scientists at the NIH's National Institute of Neurological Disorders and Stroke (NINDS) showed that a protein called PINK1...

Scientists adopt new strategy to find Huntington's disease therapies

Friday, August 7, 2015

Scientists searched the chromosomes of more than 4,000 Huntington's disease patients and found that DNA repair genes may determine when the neurological symptoms begin. Partially funded by the National Institutes of Health, the results may provide a guide for discovering new treatments for...

Crystal clear images uncover secrets of hormone receptors

Friday, July 31, 2015

Many hormones and neurotransmitters work by binding to receptors on a cell's exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level images to show how the neuropeptide hormone neurotensin might activate...

Futuristic brain probe allows for wireless control of neurons

Thursday, July 16, 2015

A study showed that scientists can wirelessly control the path a mouse walks with just a press of a button. Researchers at the Washington University School of Medicine, St. Louis, and University of Illinois, Urbana-Champaign, created a remote controlled, next-generation tissue implant that...

Progesterone does not significantly improve outcome after traumatic brain injury

Tuesday, June 16, 2015

Results of a phase 3 randomized, placebo-controlled clinical trial suggest that progesterone may not significantly improve outcomes in patients who have suffered a moderate to severe traumatic brain injury.

Normal neuronal firing may spark brain tumor growth

Tuesday, June 16, 2015

Using human brain tumor samples, scientists have discovered that normal patterns of nerve cell firing may enhance the growth of cancer cells. They also found that, neuroligin-3 (NLGN3), a gene known to be important for brain cell communication, may influence tumor growth and patient survival,...

NIH Names Walter J. Koroshetz, M.D., Director of the National Institute of Neurological Disorders and Stroke

Thursday, June 11, 2015

National Institutes of Health Director Francis S. Collins, M.D., Ph.D., announced today the selection of Walter J. Koroshetz, M.D., as the Director of the National Institute of Neurological Disorders and Stroke (NINDS). He has served as Acting Director of the NINDS since October, 2014.

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