Description:
The objectives of this protocol are to: 1) screen patients with various neuromuscular disorders and facilitate their entry into appropriate research protocols; 2) help resolve puzzling diagnostic neuromuscular problems and train fellows in the evaluation and treatment of Neuromuscular Diseases; and 3) provide follow up to patients who finished their participation in a previous study but they are not currently entered in another research protocol. No investigational treatments will be performed on this protocol but the tissues collected can be used for future research studies.
Eligibility Criteria:
- INCLUSION CRITERIA:
Research patients will be studied under this protocol if they fulfill the following
criteria:
Have an identifiable neuromuscular disorder that may be suitable for a specific current or
future protocol;
Present a diagnostic puzzle in spite of the previously performed diagnostic work-up;
Have unusual manifestation of a more usual neuromuscular disease;
Have a disorder useful for teaching purposes.
Patients should be referred by a physician who will continue their care after our
evaluation. A report of the patients' visit and tests, along with suggestions or
recommendations will be sent to each referring physician. There is a wide spectrum of
neuromuscular diseases to be studied, among them are: peripheral neuropathies, myopathies,
dystrophies, myasthenia, stiff person syndrome, muscle cramps, myotonias, motor neuron
diseases, post-polio syndrome, and certain demyelinating disorders affecting both the
central and the peripheral nervous system.
Study Design:
Study Location:
Maryland
