The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health, is looking for individuals to participate in clinical studies. Participating in clinical trials allows you to play an active role in research on the nature and causes of many disorders of the brain and nervous system, and to possibly help physician-scientists develop future treatments. The information below is designed to help you quickly learn about actively recruiting research studies for which you or someone you know may be eligible.

Description:

The purpose of this protocol is to test the hypothesis that the anatomical connectivity of occipital and somatosensory areas in early blind subjects differs from that in subjects who became blind later in life and from that in sighted volunteers.

Eligibility Criteria:

INCLUSION CRITERIA: Subjects with late blindness. Subjects with early blindness. Sighted volunteers. Age between 18 and 65 years. EXCLUSION CRITERIA: Subjects with personal or family history of seizures or other neurological or demyelinating disorders. Pregnant women tested after urine pregnancy test. Subjects with metal in the cranium except mouth. Subjects with intracardiac lines and implanted medication pumps. Subjects with increased intracranial pressure as evaluated by clinical means. Subjects with cardiac pacemakers. Intake or neuroleptics. Subjects with blindness secondary to degenerative CNS diseases.

Study Design:

Study Location:

Maryland