Locked-In Syndrome Information Page

Locked-In Syndrome Information Page


Search Disorders

What research is being done?

The NINDS supports research on neurological disorders that can cause locked-in syndrome. The goals of this research are to find ways to prevent, treat, and cure these disorders.

Information from the National Library of Medicine’s MedlinePlus
Paralysis

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What research is being done?

The NINDS supports research on neurological disorders that can cause locked-in syndrome. The goals of this research are to find ways to prevent, treat, and cure these disorders.

Information from the National Library of Medicine’s MedlinePlus
Paralysis

The NINDS supports research on neurological disorders that can cause locked-in syndrome. The goals of this research are to find ways to prevent, treat, and cure these disorders.

Information from the National Library of Medicine’s MedlinePlus
Paralysis


Definition
Definition
Treatment
Treatment
Prognosis
Prognosis
Clinical Trials
Clinical Trials
Organizations
Organizations
Publications
Publications
Definition
Definition

Locked-in syndrome is a rare neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. It may result from traumatic brain injury, diseases of the circulatory system, diseases that destroy the myelin sheath surrounding nerve cells, or medication overdose. Individuals with locked-in syndrome are conscious and can think and reason, but are unable to speak or move. The disorder leaves individuals completely mute and paralyzed. Communication may be possible with blinking eye movements

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Definition

Locked-in syndrome is a rare neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. It may result from traumatic brain injury, diseases of the circulatory system, diseases that destroy the myelin sheath surrounding nerve cells, or medication overdose. Individuals with locked-in syndrome are conscious and can think and reason, but are unable to speak or move. The disorder leaves individuals completely mute and paralyzed. Communication may be possible with blinking eye movements

Treatment
Treatment

There is no cure for locked-in syndrome, nor is there a standard course of treatment. A therapy called functional neuromuscular stimulation, which uses electrodes to stimulate muscle reflexes, may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.

×
Treatment

There is no cure for locked-in syndrome, nor is there a standard course of treatment. A therapy called functional neuromuscular stimulation, which uses electrodes to stimulate muscle reflexes, may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.

Definition
Definition

Locked-in syndrome is a rare neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. It may result from traumatic brain injury, diseases of the circulatory system, diseases that destroy the myelin sheath surrounding nerve cells, or medication overdose. Individuals with locked-in syndrome are conscious and can think and reason, but are unable to speak or move. The disorder leaves individuals completely mute and paralyzed. Communication may be possible with blinking eye movements

Treatment
Treatment

There is no cure for locked-in syndrome, nor is there a standard course of treatment. A therapy called functional neuromuscular stimulation, which uses electrodes to stimulate muscle reflexes, may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.

Prognosis
Prognosis

While in rare cases some patients may regain certain functions, the chances for motor recovery are very limited.

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While in rare cases some patients may regain certain functions, the chances for motor recovery are very limited.

Prognosis
Prognosis

While in rare cases some patients may regain certain functions, the chances for motor recovery are very limited.

Definition

Locked-in syndrome is a rare neurological disorder characterized by complete paralysis of voluntary muscles in all parts of the body except for those that control eye movement. It may result from traumatic brain injury, diseases of the circulatory system, diseases that destroy the myelin sheath surrounding nerve cells, or medication overdose. Individuals with locked-in syndrome are conscious and can think and reason, but are unable to speak or move. The disorder leaves individuals completely mute and paralyzed. Communication may be possible with blinking eye movements

Treatment

There is no cure for locked-in syndrome, nor is there a standard course of treatment. A therapy called functional neuromuscular stimulation, which uses electrodes to stimulate muscle reflexes, may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.

Prognosis

While in rare cases some patients may regain certain functions, the chances for motor recovery are very limited.

What research is being done?

The NINDS supports research on neurological disorders that can cause locked-in syndrome. The goals of this research are to find ways to prevent, treat, and cure these disorders.

Information from the National Library of Medicine’s MedlinePlus
Paralysis

Patient Organizations
National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR)
Administration for Community Living
330 C St., NW
Washington
DC
Washington, DC 20201
Tel: 202-401-4634; 202-245-7316 (TTY)
National Rehabilitation Information Center (NARIC)
8400 Corporate Drive
Suite 500
Landover
MD
Landover, MD 20785
Tel: 301-459-5900; 800-346-2742; 301-459-5984 (TTY)
National Stroke Association
9707 East Easter Lane
Suite B
Centennial
CO
Centennial, CO 80112-3747
Tel: 303-649-9299; 800-STROKES (787-6537)