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The purpose of this notice is to inform applicants of an extension of PAR-21-234 "NINDS Faculty Development Award to Promote Diversity in Neuroscience Research (K01 Independent Clinical Trial Not Allowed)" by one additional council round.

The purpose of this notice is to inform applicants of an extension to PAR-21-328 "Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Not Allowed)".

The purpose of this notice is to inform applicants of an extension to PAR-21-327 "Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)".

The purpose of this notice is to inform applicants of an extension to PAR-21-122, PAR-21-123, PAR-21-123 Innovation Grants to Nurture Initial Translational Efforts (IGNITE) NOFOs by one additional council round.

The purpose of this notice is to inform applicants of an extension of PAR-21-2137 "NINDS Efficacy Clinical Trials (UG3/UH3 Clinical Trial Required)" by two additional council rounds.

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This Notice of Special Interest (NOSI) encourages the translation of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative-supported technologies from academic and other non-small business research sectors to the marketplace. Small Business Concerns (SBCs) are encouraged to submit Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grant applications that propose to further develop, optimize, validate and scale such technologies for commercial dissemination. Additionally, SBIR and STTR applications supporting the development and commercialization of novel technologies that fit within the mission of the BRAIN Initiative are encouraged.

The purpose of this Notice is to alert the research community that theNational Institute of Neurological Disorders and Stroke (NINDS) will consider adherence to Findable, Accessible, Interoperable, and Reusable (FAIR) data practices and leveraging of existing NIH- and NINDS-supported data infrastructure in its strategic and budgetary prioritization decision-making processes. NINDS iscommitted to the development of a resource-efficient and interoperable data ecosystem that strikes a balance between maximizing data harmonization and enabling innovation. Developing such a data ecosystem is consistent with multiple cross-cutting strategies outlined in theNINDS Strategic Plan including Rigor and Transparency, Technology Access, and Data Sharing and Data Science. Moreover, in a limited resource environment, the development of this type of data ecosystem will provide cost savings that can be used to fund more research. Accomplishing this goal necessitates a strong expectation that applicants to NINDS will leverage existing NINDS-supported data infrastructure and resources, harmonize their data to existing NIH or NINDS data standards for interoperability, and adopt NINDS-supported standard operating procedures for biospecimen collection whenever applicable. Applicants proposing something that overlaps with or is incompatible with existing resources will need an especially strong justification for NINDS to accept an ARA request over $500K or fund the application.

The Transformative Research to Address Health Disparities and Advance Health Equity initiative is soliciting applications to support unusually innovative intervention research addressing social determinants of health (SDOH), which, if successful, would have a major impact on preventing, reducing, or eliminating health disparities and advancing health equity. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact on advancing NIHs commitment to addressing SDOH to accelerate progress in improving health for all. Preliminary data are not required for this initiative.

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