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Notice Change Earliest Start Date Applications Submitted RFA-DA-14-002 Short-term Mentored Career Enhancement Awards the Basic Behavioral Social Sciences: Cross-Training the Intersection Animal Models Human Investigation K18)" Notice Number: NOT-DA-13-040 Key Dates Release Date: June 24, 2013 Related Announcements RFA-DA-14-002 Issued NIH Basic Behavioral amp; Social Science Opportunity Network OppNet) behalf its constituent organizations: National Cancer Institute NCI) National Eye Institute NEI) National Heart, Lung, Blood Institute NHLBI) National Human Genome Research Institute NHGRI) National Institute Aging NIA) National Institute Alcohol Abuse Alcoholism NIAAA) National Institute Allergy Infectious Diseases NIAID) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Biomedical Imaging Bioengineering NIBIB) Eunice Kennedy Shriver National Institute Child Health Human Development NICHD) National Institute Deafness Other Communication Disorders NIDCD) National Institute Dental Craniofacial Research NIDCR) National Institute Diabetes Digestive Kidney Diseases NIDDK) National Institute Drug Abuse NIDA) National Institute Environmental Health Sciences NIEHS) National Institute General Medical Sciences NIGMS) National Institute Mental Health NIMH) National Institute Neurological Disorders Stroke NINDS) National Institute Nursing Research NINR) National Institute Minority Health Health Disparities NIMHD) National Library Medicine NLM) Fogarty International Center FIC) National Center Complementary Alternative Medicine NCCAM) National Center Advancing Translational Sciences NCATS) Division Program Coordination, Planning Strategic Initiatives, Office Research Infrastructure Programs ORIP) Office Behavioral Social Sciences Research OBSSR) Office Dietary Supplements ODS) Office Research Women’s Health ORWH) Purpose notice changes start date RFA-DA-14-002 quot;Short-term Mentored Career Enhancement Awards the Basic Behavioral Social Sciences:  Cross-Training the Intersection Animal Models Human Investigation K18)". Currently reads: Earliest Start Date December 2014 Modified read: Earliest Start Date September 2014 other aspects the FOA remain same. Inquiries Please direct inquiries to: Minda Lynch, PhD National Institute Drug Abuse NIDA) Telephone: 301-435-1322 Email: mlynch1@mail.nih.gov Melissa S. Gerald, Ph.D. Division Behavioral Social Research National Institute Aging NIA) Phone: 301-402-4156 Email: melissa.gerald@nih.gov

Notice Intent Publish Funding Opportunity Announcement NINDS Clinical Trial Methodology Course R25) Notice Number: NOT-NS-13-030 Key Dates Release Date: June 14, 2013 Estimated Publication Date Announcement: August 2013 First Estimated Application Due Date: October 2013  Earliest Estimated Award Date: March 2014  Earliest Estimated Start Date: 2014 Issued National Institute Neurological Disorders Stroke NINDS) Purpose National Institute Neurological Disorders Stroke NINDS) intends issue Funding Opportunity Announcement FOA) solicit applications the NINDS Clinical Research Methods Course. goal this initiative to enhance training new investigators the conduct high-quality clinical trials. Notice being provided allow potential applicants sufficient time develop meaningful collaborations responsive projects.  FOA expected be published summer 2013 an expected application due date Fall 2013. FOA utilize R25 activity code. Details the planned FOA provided below. Research Initiative Details NINDS Clinical Research Methods Clinical Neurological Disorders course use R25 grant mechanism support educational course faculty any clinical neuroscience subspecialty introduce to principles good clinical trial design exposing early career clinical scientists the full spectrum challenges clinical research. NINDS aims develop cadre well-trained researchers whose expertise foster better clinical study design thereby lead improved regimens therapy prevention neurological disorders. is anticipated this annual course yield group talented, dedicated clinical neuroscience researchers will consequently in position obtain funding their own high quality clinical research.  the program successful, is anticipated participant scholars return their organizations/institutions where will take prominent role advancing local clinical research priorities neurology.  achieve objective, NINDS requires high-impact program enhancing training future researchers is innovative that exceeds training experiences available those treating neurological disease.  important part the NINDS extramural clinical trials budget spent early phase trials phase 1, 2, pilot trials) that primary focus this grant on training early phase clinical trials. Specific performance goals the FOA are: develop scientific content, curriculum, format a comprehensive, hands-on educational program incorporating innovative methods teaching conducting clinical research taking advantage knowledge gained disciplines outside neurology, emphasis proof principle studies new therapeutic agents, validating biomarkers use early phase clinical trials. organize conduct educational program, including recruitment selection faculty participants.  conduct formal evaluation the program and, where relevant, incorporate results subsequent course offerings. maximize course impact making didactic material available online the additional benefit a wider audience. is expected the grant tasks be performed two phases.  Phase comprises development the education program; Phase II includes conducting iteration the course course evaluation. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: Robin Conwit, MD Program Director Office Clinical Research National Institute Neurological Disorders Stroke Telephone: 301) 496-9135 Fax: 301) 410-1080 Email: Robin.Conwit@nih.gov nbsp;

Notice Participation Additional NIH Institutes Centers PAR-13-208 Countermeasures Against Chemical Threats CounterACT) Cooperative Research Projects U01) Notice Number: NOT-NS-13-029 Key Dates Release Date: 14, 2013 Related Announcements PAR-13-208 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to inform potential applicants the participation additional NIH Institutes, effective immediately, Funding Opportunity Announcement FOA) PAR-13-208. following sections PAR-13-208 been updated reflect participation NEI, NIAID, NIAMS, NIEHS this FOA. Part 1. Overview Information Components Participating Organizations National Institute Neurological Disorders Stroke NINDS) National Eye Institute NEI) National Institute Allergy Infectious Diseases NIAID) National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) National Institute Environmental Health Sciences NIEHS) National Institute General Medical Sciences NIGMS) Catalog Federal Domestic Assistance CFDA) Number(s) 93.853; 93.867; 93.855; 93.856; 93.846; 93.113; 93.859  Part 2. Section VII. Agency Contacts Scientific/Research Contact(s)       Houman Araj, Ph.D. National Eye Institute NEI) Telephone: 301-451-2020 Email: arajh@nei.nih.gov Gennady E. Platoff Jr., Ph.D. National Institute Allergy amp; Infectious Diseases NIAID) Telephone: 301-451-4418 Email: platoffg@niaid.nih.gov Hung Tseng, Ph.D. National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) Telephone: 301-594-5032 Email: tsengh@mail.nih.gov Srikanth S. Nadadur, Ph.D. National Institute Environmental Health Sciences NIEHS) Telephone: 919-541-5327 Email: nadadurs@niehs.nih.gov Financial/Grants Management Contact(s) William W. Darby Grants Management Branch National Eye Institute NEI) Telephone: 301-451-2020 Email: darbyw@mail.nih.gov Victoria Connors Grants Management Branch National Institute Allergy amp; Infectious Diseases NIAID) Telephone: 301-402-5065 Email: connorssv@niaid.nih.gov Melinda B. Nelson Grants Management Branch National Institute Arthritis Musculoskeletal Skin Diseases NIAMS) Telephone: 301-435-5278 Email: nelson@mail.nih.gov Lisa Archer Edwards, MBA Grants Management Branch National Institute Environmental Health Sciences NIEHS) Telephone: 919-541-0751  Email:  archer@niehs.nih.gov Inquiries Please direct inquiries to: David A. Jett, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-6035  Email: jettd@ninds.nih.gov

Notice Correction the Review Selection Process RFA-NS-13-014 quot;Pilot Projects Sports-Related Brain Spinal Cord Injury R21)" Notice Number: NOT-NS-13-025 Key Dates Release Date:  April 19, 2013   Related Announcements RFA-NS-13-014    Issued National Institute Neurological Disorders Stroke NINDS) Purpose National Institute Neurological Disorders Stroke NINDS) correcting process the selection grants fund RFA-NS-13-014 quot;Pilot Projects Sports-Related Brain Spinal Cord Injury R21)" include review the NIH Institute's Advisory Council which grant been given primary assignment. CURRENTLY READS: Review Selection Process Following initial peer review, recommended applications receive second level review the National Advisory Neurological Disorders Stroke NANDS) Council. CHANGED READ: Review Selection Process Following initial peer review, recommended applications receive second level review the NIH Institute's Advisory Council which grant been given primary assignment. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Ramona Hicks, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1447 Email: hicksra@mail.nih.gov

Notice Correction the Review Selection Process RFA-NS-13-015 quot;Pilot Projects Sports-Related Brain Spinal Cord Injury R03)" Notice Number: NOT-NS-13-026 Key Dates Release Date:   April 19, 2013 Related Announcements RFA-NS-13-015     Issued National Institute Neurological Disorders Stroke NINDS)) Purpose National Institute Neurological Disorders Stroke NINDS) correcting process the selection grants fund RFA-NS-13-015 quot;Pilot Projects Sports-Related Brain Spinal Cord Injury R03)" include review the NIH Institute's Advisory Council which grant been given primary assignment. CURRENTLY READS: Review Selection Process Following initial peer review, recommended applications receive second level review the National Advisory Neurological Disorders Stroke NANDS) Council. CHANGED READ: Review Selection Process  Following initial peer review, recommended applications receive second level review the NIH Institute's Advisory Council which grant been given primary assignment. other aspects this FOA remain unchanged. Inquiries Please direct inquiries to: Ramona Hicks, PhD National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1447 Email: hicksra@mail.nih.gov

Notice Clarification Responsive Projects RFA-NS-13-009 quot;High Impact Neuroscience Research Resource Grants R24)" Notice Number: NOT-NS-13-024 Key Dates Release Date: April 12, 2013 Related Announcements RFA-NS-13-009 NOT-MH-12-020 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to clarify project eligibility for RFA-NS-13-009 "High Impact Neuroscience Research Resource Grants R24)".   accordance a recent change funding support repositories brain related bio-specimens NOT-MH-12-020), NINDS not accept applications proposing activities submitted response RFA-NS-13-009 . Inquiries Please direct inquiries to: Edmund Talley, Ph.D. National Institute Neurological Disorders Stroke NINDS) Telephone: 301-496-1917 Email strongly preferred): TalleyE@mail.nih.gov

Notice Extend Expiration Date PAR-10-199 quot;NINDS Exploratory Clinical Trials R01)" Notice Number:  NOT-NS-13-022 Key Dates Release Date: March 25, 2013 Related Announcements PAR-10-199 Issued National Institute Neurological Disorders Stroke NINDS) Purpose NINDS gives notice the extension the expiration date PAR-10-199 quot;NINDS Exploratory Clinical Trials R01)" until September 8, 2013. Current Expiration Date: 8, 2013 New Expiration Date: September 8, 2013 other aspects the FOA remain unchanged. Inquiries Please direct inquiries to: Peter R. Gilbert, Sc.M. National Institute Neurological Disorders Stroke Telephone: 301) 496-0870 Email: Peter.Gilbert@nih.gov

Notice Extend Expiration Date PAR-11-173 quot;NINDS PHASE III Investigator-Initiated Multi-Site Clinical Trials U01)" Notice Number: NOT-NS-13-023 Key Dates Release Date:   March 25, 2013   Related Announcements PAR-11-173 Issued National Institute Neurological Disorders Stroke NINDS) Purpose NINDS gives notice the extension the expiration date PAR-11-173 quot;NINDS PHASE III Investigator-Initiated Multi-Site Clinical Trials U01)" until September 8, 2013. other aspects the FOA remain unchanged. Inquiries Please direct inquiries to: Scott Janis, PhD National Institute Neurological Disorders Stroke Telephone: 301) 496-9135 Email: Scott.Janis@nih.gov

Pre-application Information Webinars the NINDS Stroke Trials Network Notice Number: NOT-NS-13-021 Key Dates Release Date: March 22, 2013 Related Announcements RFA-NS-13-011 RFA-NS-13-012 Issued National Institute Neurological Disorders Stroke NINDS) Purpose purpose this Notice to inform potential applicants pre-application webinars provide submission information the NINDS Stroke Trials Network. new network designed develop conduct high-quality, multi-site clinical trials focused key interventions stroke prevention, treatment, recovery the objective have balanced portfolio between three approaches.  Exploratory phase 1, 2 confirmatory phase 3 clinical trials well biomarker-validation studies are immediately preparatory trials be coordinated through separate National Clinical Coordinating Data Management Centers. intent the webinars to provide overview the initiative to address questions pertinent preparing applications.  webinars optional not required application submission. Webinars Information Date: Monday, April 1, 2013 Time: 12:00 PM - 1:00 PM EDT Meeting URL: https://www2.gotomeeting.com/join/407718530 Call-in number: 800-779-5339 Participant passcode: 53789 Date: Friday, April 5, 2013 Time: 12:00 PM - 1:00 PM EDT Meeting URL: https://www2.gotomeeting.com/join/521813330 Call-in number: 800-779-5339 Participant passcode: 53789 Space limited. Questions be submitted email either beforehand during webinar.  Please put Webinar question” the subject line, send the following email address: Stroke_Network@mail.nih.gov. While every effort be to answer questions during webinar, is possible not will addressed during meeting due time constraints. applicants strongly encouraged discuss applications the appropriate NIH Scientific/Research Contact Financial/Grants Management Contact listed the FOA early possible. complete text the FOAs available http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-13-011.html http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-13-012.html. Inquiries Please direct inquiries to: Scott Janis, PhD Program Director NINDS Office Clinical Research Telephone: 301-496-9135 Email: Scott.Janis@nih.gov

Notice Modification the Data Sharing Policy the Federal Interagency Traumatic Brain Injury Research FITBIR) Informatics System Notice Number: NOT-NS-13-018 Key Dates Release Date:  March 21, 2013 Related Announcements NOT-NS-12-016 NOT-NS-12-017    Issued National Institute Neurological Disorders Stroke NINDS) Purpose Data Sharing Policy the Federal Interagency Traumatic Brain Injury Research FITBIR) Informatics System modified. overall document been shortened reorganized make clearer more concise.  Also, Data Submission Data Sharing Schedules been modified greater clarity feasibility follows:   Data Submission Schedule Data include research clinical assessments information obtained via interviews, direct observations, laboratory tasks procedures, records reviews, genetic genomic data, neuroimaging data, neuropsychological assessments, data physical examinations, etc. addition, supporting documentation is needed enable investigator unfamiliar the dataset understand use data also required.  example, supporting documentation include non-copyrighted data collection forms, study procedures protocols, data dictionary rationale, exclusion criteria, website references, listing major study publications, the definition a genomic analysis protocol.  following not included data:  laboratory notebooks, preliminary analyses, drafts scientific papers, plans future research, peer review reports, communications colleagues, physical objects, such gels laboratory specimens. data be submitted FITBIR a quarterly basis according the following schedule: Data collection period Quarterly upload due: January 1 – March 31 June 30 April 1 – June 30 September 30 July 1 – September 30 December 31 October 1 – December 31 March 31 Data Sharing Schedule Six months after end the performance period the grant, data be available other researchers have submitted data FITBIR Submitters). Twelve months after end the grant contract, data be open all qualified approved researchers Recipients). Performance Period Research Study Ends Data Available FITBIR Submitters” Data Available All Approved FITBIR Data Recipients” Time 0   6 months 12 months Investigators also strongly encouraged collaborate share data throughout study accelerate research advance knowledge TBI. Inquiries Please direct inquiries to: FITBIR Operations Team Email: FITBIR-ops@mail.nih.gov Website: https://fitbir.nih.gov/