Workshop on Status Epilepticus after Benzodiazepines: Seizures and Improving Long Term Outcomes

Status Epilepticus after Benzodiazepines: Seizures and Improving Long Term Outcomes

The recent approval of intramuscular midazolam (Seizalam®) for acute treatment of status epilepticus (SE) is an important advancement for the treatment of epilepsy and chemical nerve agent exposures. However, effective treatments that improve neuropathic outcomes after SE becomes refractory to benzodiazepines is a common unmet need for both epilepsy and nerve agent researchers. 

This virtual workshop will convene preclinical and clinical researchers, as well as relevant stakeholders to discuss and define the indications of potential therapeutics needed to improve outcomes following SE. Topics of discussion will include refractory SE, post SE neuropathology, current clinical trials, gaps in the research for follow-on treatments and barriers to transitioning therapies to the clinic. Outcomes of the workshop will include a clearer understanding of the unmet therapeutic needs and identification of key gaps in the research, increasing the potential for new therapeutics development.

Keynote Speakers

Jonathan Newmark, MD    

Senior Medical Officer, Office of Biodefense Research and Surety                                                        National Institute of Allergy and Infectious Diseases;
Adjunct Professor of Neurology, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences
Department of Neurology, Washington DC Veterans Affairs Medical Center

Jaideep Kapur, MBBS, PhD    

Eugene Meyer III, Professor of Neuroscience and Neurology                                         
Director, University of Virginia, Brain Institute

Amy Brooks-Kayal, MD 

Professor and Chair, Department of Neurology                                                   
Andrew John Gabor, MD, PhD Presidential Endowed Chair                     
Co-Director, UC Davis CounterACT Center of Excellence
University of California, Davis, School of Medicine

Pam Lein, PhD      

Professor of Neurotoxicology             
Chair, Department of Molecular Biosciences                                                 
Director, UC Davis CounterACT Center of Excellence           
University of California, Davis, School of Veterinary Medicine


Agenda & Presentations
A schedule of events and sessions that took place during each day of the workshop. You can also access the speaker slides.
Speakers and Moderators
Read more about the experts who gave oral presentations and moderated discussions at the workshop.
Poster Session
Access abstracts of the posters presented.
A selection of background resources for workshop attendees.